Parida, Chandrakanta; Maity, Rajendra; Chandra Sahoo, Subas; Chandra Pan, Subhas published the artcile< α-Nitro-α,β-Unsaturated Ketones: An Electrophilic Acyl Transfer Reagent in Catalytic Asymmetric Friedel-Crafts and Michael Reactions>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is nitroethylnaphthyl ester enantioselective preparation; nitroethyl substituted enol ester enantioselective preparation; squaramide catalyst enantioselective tandem Friedel Crafts acyl transfer reaction; nitroenone acyl transfer reagent enantioselective reaction naphthol phenol.
In the presence of a tert-leucine-derived squaramide and mol. sieves, 2-naphthols and electron-rich phenols underwent tandem enantioselective Friedel-Crafts and acyl transfer reactions with α-nitro-α,β-unsaturated ketones such as I (R = Ph, 4-i-PrC6H4, 4-PhOC6H4, 4-FC6H4, 4-ClC6H4, 4-BrC6H4, 4-PhC6H4, 3-BrC6H4, 2,4-Me2C6H3, 2-naphthyl, cyclohexyl, i-Pr; R1 = Ph, 4-MeC6H4, 4-MeOC6H4, 4-ClC6H4, 4-BrC6H4, 4-O2NC6H4, 3-ClC6H4, 3-F3CC6H4, 2-FC6H4, 2-ClC6H4, 2-Br-4-MeC6H3, 2-furyl) to yield nitroethylnaphthol ester such as II (R = Ph, 4-i-PrC6H4, 4-PhOC6H4, 4-FC6H4, 4-ClC6H4, 4-BrC6H4, 4-PhC6H4, 3-BrC6H4, 2,4-Me2C6H3, 2-naphthyl, cyclohexyl, i-Pr; R1 = Ph, 4-MeC6H4, 4-MeOC6H4, 4-ClC6H4, 4-BrC6H4, 4-O2NC6H4, 3-ClC6H4, 3-F3CC6H4, 2-FC6H4, 2-ClC6H4, 2-Br-4-MeC6H3, 2-furyl). Dimedone and a pyrazolone underwent tandem enantioselective Michael and acyl transfer reactions with I (R = R1 = Ph) to yield nitroethyl-substituted enol esters. Further reactions of II (R = R1 = Ph) are disclosed.
Organic Letters published new progress about Alkenes, nitro Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (α-acyl). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics