Uvyn, Annemiek; De Coen, Ruben; De Wever, Olivier; Deswarte, Kim; Lambrecht, Bart N.; De Geest, Bruno G. published the artcile< Cell surface clicking of antibody-recruiting polymers to metabolically azide-labeled cancer cells>, Name: Perfluorophenyl acrylate, the main research area is antibody recruiting polymer tumor binding innate immunity.
Triggering antibody-mediated innate immune mechanisms to kill cancer cells is an attractive therapeutic avenue. In this context, recruitment of endogenous antibodies to the cancer cell surface could be a viable alternative to the use of monoclonal antibodies. We report on antibody-recruiting polymers containing multiple antibody-binding hapten motifs and cyclooctynes that can covalently conjugate to azides introduced onto the glycocalyx of cancer cells by metabolic labeling with azido sugars.
Chemical Communications (Cambridge, United Kingdom) published new progress about Animal tissue culture (2D, 3D). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Name: Perfluorophenyl acrylate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics