Oehlke, J.; Schroetter, E.; Dove, S.; Schick, H.; Niedrich, H. published the artcile< Preparation of some 4- and 5-substituted pyridine-2-carboxylic acids as fusaric acid analogs>, Formula: C19H34O2, the main research area is pyridinecarboxylic acid dopamine hydroxylase inhibitor; fusaric acid dopamine hydroxylase inhibitor.
5-Substituted picolinic acids I (R = NO2, NH2, NHAc, NHCOEt, NHOH, iodo, Br, OH, MeO, PrO, BuO; R1 = H) and 4-substituted fusaric acids I (R = Bu, R1 = NO2, MeO, EtO, Cl, NH2, NHOH, Me), selected by a random sampling procedure suitable for small series, were prepared for future studies on the structure-activity relationships involved in the inhibition of dopamine β-hydroxylase. The known preparation of I (R = NO2, R1 = H) via a Rosenmund-von Braun reaction with 2-bromo-5-nitropyridine was significantly improved. I (R = OH, R1 = H), easily accessible via the same method, was converted into 5-alkoxypicolinic acids by reaction with alkyl halides in DMSO in the presence of Ag2O. I (R = Bu) were prepared via 5-butyl-2-methyl-4-nitropyridine N-oxide.
Pharmazie published new progress about Antihypertensives. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics