Koevilein, Aline; Aschmann, Vera; Hohmann, Silja; Ochsenreither, Katrin published the artcile< Immobilization of Aspergillus oryzae DSM 1863 for L-Malic Acid Production>, Application of C19H34O2, the main research area is Aspergillus oryzae malic acid production immobilization.
Whole-cell immobilization by entrapment in natural polymers can be a tool for morphol. control and facilitate biomass retention. In this study, the possibility of immobilizing the filamentous fungus Aspergillus oryzae for L-malic acid production was evaluated with the two carbon sources acetate and glucose. A. oryzae conidia were entrapped in alginate, agar, and κ-carrageenan and production was monitored in batch processes in shake flasks and 2.5-L bioreactors. With glucose, the malic acid concentration after 144 h of cultivation using immobilized particles was mostly similar to the control with free biomass. In acetate medium, production with immobilized conidia of A. oryzae in shake flasks was delayed and titers were generally lower compared to cultures with free mycelium. While all immobilization matrixes were stable in glucose medium, disintegration of bead material and biomass detachment in acetate medium was observed in later stages of the fermentation Still, immobilization proved advantageous in bioreactor cultivations with acetate and resulted in increased malic acid titers. This study is the first to evaluate immobilization of A. oryzae for malic acid production and describes the potential but also challenges regarding the application of different matrixes in glucose and acetate media.
Fermentation published new progress about Aspergillus oryzae. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics