Bur, Daniel; Luyten, Marcel A.; Wynn, Hla; Provencher, Louis R.; Jones, J. Bryan; Gold, Marvin; Friesen, James D.; Clarke, Anthony R.; Holbrook, J. John published the artcile< Enzymes in organic synthesis. 45. An evaluation of the substrate specificity and asymmetric synthesis potential of the cloned L-lactate dehydrogenase from Bacillus stearothermophilus>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is lactate dehydrogenase synthesis; keto acid enzymic reduction; hydroxy acid preparation enzymic.
The potential utility of the L-lactate dehydrogenase of B. stearothermophilus (BSLDH) for stereospecific, preparative-scale reductions of α-keto acids to (S)-α-hydroxy acids of >99% enantiomeric excess has been demonstrated. BSLDH is a stable, thermophilic, enzyme whose gene has been cloned into a high-expression vector to assure its plentiful supply. Its specificity for keto acid substrates possessing straight- and branched-chain alkyl, cyclopropyl, or Ph groups has been evaluated in preparative and kinetic terms, and compared with that of the mammalian pig heart enzyme (PHLDH). The specificities of BSLDH and PHLDH are similar, with branched alkyl-chain keto acids being poor substrates for both enzymes.
Canadian Journal of Chemistry published new progress about Enzyme kinetics. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics