Azzena, Ugo; Demartis, Salvatore; Fiori, Maria Giovanna; Melloni, Giovanni; Pisano, Luisa published the artcile< Reductive electrophilic substitution of phthalans and ring expansion to isochroman derivatives>, Category: esters-buliding-blocks, the main research area is reductive ring cleavage phthalan lithium; isochromanone preparation phthalan ring expansion; lithiomethylbenzyl alkoxide cycloaddition carbon dioxide; electrophilic alkylation lithiomethylbenzyl alkoxide; benzyl alc substituted preparation.
Reductive cleavage of phthalans I (R1 = H, R2 = H, Ph; R1R2 = CH2CH2) with Li and a catalytic amount of naphthalene forms stable aromatic dilithium compounds II, which undergo ring closure with CO2 to form isochromans III in yields >40%. II react with various alkyl halides, aldehydes and ketones to form o-substituted benzyl alcs. in yields > 60%.
Tetrahedron Letters published new progress about Electrophilic substitution reaction. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics