Guggisberg, Yves; Faigl, Ferenc; Schlosser, Manfred published the artcile< Optional ortho or alpha hydroxymethylation of alkylarenes>, Synthetic Route of 112-63-0, the main research area is regioselective hydroxymethylation alkylarene; alkanol aryl; benzyl alc alkyl.
Treatment of arenes carrying Me or primary alkyl groups, e.g., EtPh, in THF with potassium tert-butoxide activated butyllithium followed by reaction with formaldehyde gives 2-arylalkanols, e.g., PhCHMeCH2OH. In contrast, if prior to the addition of the electrophile a stoichiometric amount of magnesium dibromide is added then the regioisomeric 2-alkylbenzyl alcs., e.g., 2-EtC6H4CH2OH, are formed.
Journal of Organometallic Chemistry published new progress about Regiochemistry. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics