Kazmierski, Wieslaw M’s team published research in Tetrahedron Letters in 1995-12-11 | 112-63-0

Tetrahedron Letters published new progress about Affinity chromatography. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Kazmierski, Wieslaw M.; McDermed, John published the artcile< Synthesis of the carbonic acid benzotriazol-1-yl-ester-(2-biotinylamino)-9H-fluoren-9-ylmethyl ester: a convenient transient-biotinylation reagent for use in affinity chromatography>, HPLC of Formula: 112-63-0, the main research area is biotinylaminofluorenylmethoxycarbonyl peptide protective group preparation; affinity chromatog biotinylated fluorenylmethoxycarbonyl peptide.

Stepwise synthesis of hydrophobic peptides frequently yields deletion products, which often require extensive purification and identification. A new transient-biotinylation reagent I was prepared, which was conveniently used in affinity chromatog. of crude products to afford pure peptides. Unlike conventional affinity chromatog., reagent I leads to free N-terminal peptides, which are thus amenable to further chem. manipulations.

Tetrahedron Letters published new progress about Affinity chromatography. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics