Li, Sun; Wang, Lei; Chauhan, Pankaj; Peuronen, Anssi; Rissanen, Kari; Enders, Dieter published the artcile< Asymmetric Synthesis of Five-Membered Spiropyrazolones via N-Heterocyclic Carbene (NHC)-Catalyzed [3+2] Annulations>, Quality Control of 112-63-0, the main research area is spiropyrazolone preparation enantioselective diastereoselective; enal unsaturated pyrazolone annulation heterocyclic carbene catalyst.
A new synthetic strategy for the asym. synthesis of five-membered spiropyrazolones via N-heterocyclic carbene-catalyzed [3+2] annulations employing enals and unsaturated pyrazolones as substrates has been developed. The new protocol allows the flexible variation of all four substituents of the pharmaceutically important spiropyrazolones in moderate to very good yields and in most cases with excellent diastereoselectivities and good to excellent enantioselectivities.
Synthesis published new progress about Cyclization ([3+2]). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics