Month: February 2023

AlCl₃-promoted [3 + 2] annulation of cis-2,3-disubstituted cyclopropane 1,1-diesters with isothiocyanates: stereoselective synthesis of densely substituted 2-iminodihydrothiophenes was written by Sun, Yongxian;Yang, Gaosheng;Chai, Zhuo;Mu, Xiaolong;Chai, Jun. And the article was included in Organic & Biomolecular Chemistry in 2013.Related Products of 2740-88-7 This article mentions the following:

Cis-2,3-Disubstituted cyclopropane 1,1-diesters were found to be much more reactive than their corresponding trans-isomers in the AlCl₃-promoted [3 + 2]-annulations with isothiocyanates. The reaction with the cis-cyclopropanes proceeded to completion within minutes, providing a variety of densely substituted diastereomerically pure 2-iminodihydrothiophenes in moderate to excellent yields. In the experiment, the researchers used many compounds, for example, 4-Fluorobenzylisothiocyanate (cas: 2740-88-7Related Products of 2740-88-7).

4-Fluorobenzylisothiocyanate (cas: 2740-88-7) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120鎺?C閳ユ弲閳ユ彊 and O閳ユ弲閳ユ彊 angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C閳ユ彊閳ユ弲 bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Related Products of 2740-88-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Toughening and reinforcing waste polypropylene with POE / nano-SiO₂ under elongational flow was written by He, Hezhi;Gao, Jun;Wang, Yi;Zhu, Zhiwen;Liu, Yufan;Tian, Guidong;Xu, Li;Huang, Zhaoxia. And the article was included in Journal of Applied Polymer Science in 2022.COA of Formula: C73H108O12 This article mentions the following:

Due to the white pollution, the recycling of waste plastics has attracted more and more attention. In this research, waste polypropylene/Ethylene-octene elastomer/nano-SiO₂ composites (wPP/POE/SiO₂) were melt-blended using an Eccentric Rotor Extruder (ERE) dominated by elongational flow field and a Torque Rheometer (TR) dominated by shear flow field, resp. The micromorphol., mech., crystallization, thermal and rheol. properties of wPP/POE/SiO₂ blends were studied. Compared to the blends fabricated by TR, the wPP/POE/SiO₂ blends with different compositions fabricated by ERE showed higher tensile strength, flexural strength, and modulus. Particularly, without sacrificing the tensile strength, the notched impact strength of the wPP/POE/SiO₂ blends fabricated by ERE increased to 13.53 kJ/m², a factor of 3 times larger than that of neat wPP. The enhancement of impact strength of the wPP/POE/SiO₂ blends fabricated by ERE could be ascribed to the good dispersion of POE under elongational flow and the increase of PP crystallinity. The finding from this work provides an efficient way to recycle wPP. In the experiment, the researchers used many compounds, for example, 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8COA of Formula: C73H108O12).

2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.COA of Formula: C73H108O12

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Valorisation of Roman chamomile (Chamaemelum nobile L.) herb by comprehensive evaluation of hydrodistilled aroma and residual non-volatile fractions was written by Baranauskiene, Renata;Venskutonis, Petras Rimantas;Ragazinskiene, Ona. And the article was included in Food Research International in 2022.HPLC of Formula: 659-70-1 This article mentions the following:

Valorization of botanicals for the development of natural food-grade ingredients is an important task in terms of sustainability and processing waste reduction In this study, Roman chamomile (Chamaemelum nobile L.) herb was collected at six different vegetation phases in the period 26 May – 23 August 2019 and subjected to biorefining into the several valuable fractions. The yield of hydro-distilled essential oil (EO) was in the range of 0.22% (intensive vegetative growth) to 0.80% (full flowering). Angelic, isobutyric, butyric and methacrylic acid esters and some monoterpene and sesquiterpene derivatives were the major EO constituents: 3-methylpentyl angelate (20.11-27.56%), methallyl angelate (7.28-10.33%), isoamyl angelate (5.57-9.02%), iso-Bu angelate (4.84-6.79%), 2-methylbutyl angelate (3.11-6.32%), 3-methylamyl methacrylate (5.04-6.17%), 3-methylpentyl isobutyrate (4.29-6.64%), 3-methylamyl isobutyrate (4.29-6.64%), 浼?pinene (1.61-6.37%) and pinocarvone (1.46-4.67%). In order to valorize water soluble and solid EO distillation residues their antioxidant potential was evaluated by several in vitro assays: water extracts were considerably stronger antioxidants than acetone extracts isolated from the solid residues. Water extracts of the plants collected at flowering phases were the strongest antioxidants; their TPC, FRAP and ORAC values were up to 143.2 mg gallic acid equivalent/g, 650, and 5601 娓璵ol TE/g dry extract, resp., while effective concentrations (EC50) of DPPH閳?and ABTS閳? scavenging, were down to 0.59 and 0.49 mg/mL, resp. Among 7 tentatively identified by UPLC/Q-TOF/MS phenolic constituents the intensity of mol. ion of 3,5-dicaffeoyl quinic acid was the largest. The results obtained may assist for developing flavorings, antioxidants and health beneficial preparations from C. nobile extracts In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1HPLC of Formula: 659-70-1).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is 绾?valerolactone.HPLC of Formula: 659-70-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Analysis of 16 phthalate esters in wastewater from textile plants using headspace solid-phase microextraction and gas chromatography with mass spectrometric detection was written by Li, Ying;Ye, XiWen;Niu, ZengYuan;He, Jing;Luo, Xin;Ma, Qiang. And the article was included in Textile Research Journal in 2021.Synthetic Route of C20H26O4 This article mentions the following:

Solid-phase microextraction (SPME) with a 100-娓璵 polydimethylsiloxane (PDMS) fiber coupled to gas chromatog.-mass spectrometry was used to determine 16 phthalate esters (PAEs) in wastewater from textile processing plants. Some of the 16 PAEs that exist as mixtures of isomers were identified and quantified. We investigated the matrix effect and evaluated a qualification and quantitation method for determining trace amounts of PAEs in wastewater from textile processing plants. The major advantages of this approach are the reduced matrix effects from the textile wastewater and the compatibility with the standard addition method (SAM) for PAE quantitation. Moreover, the developed method has low reagent and solvent consumption, does not require clean-up or evaporation steps and involves minimal sample manipulation. Two fiber coatings, 85-娓璵 polyacrylate and 100-娓璵 PDMS, were tested. The variables affecting SPME absorption, such as the sample temperature, extraction time and salt concentration, were studied. The final conditions were an extraction temperature of 95鎺矯, an extraction time of 30 min and a salt concentration of 0.3 g/mL. The SAM was used to analyze and quantify samples. The linear range was between 5 and 20 娓璯/L, and the limits of detection of the method were between 0.5 and 5 娓璯/L. Finally, the precision of the phthalate quantitation was also evaluated. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Synthetic Route of C20H26O4).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Synthetic Route of C20H26O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Radical Aza-Cyclization of 浼?Imino-oxy Acids for Synthesis of Alkene-Containing N-Heterocycles via Dual Cobaloxime and Photoredox Catalysis was written by Tu, Jia-Lin;Liu, Jia-Li;Tang, Wan;Su, Ma;Liu, Feng. And the article was included in Organic Letters in 2020.Synthetic Route of C12H14O3 This article mentions the following:

Nitrogen-containing heterocycles are prevalent in both naturally and synthetically bioactive mols. We report herein an unprecedented protocol for radical aza-cyclization of 浼?imino-oxy acids with pendant alkenes via synergistic photoredox and cobaloxime catalysis. With or without alkenes as the intermol. cross-coupling partners, the transformation provides a variety of corresponding alkene-containing dihydropyrrole products in satisfactory yields. In the presence of external alkenes, the tandem reaction generates E-selective coupling products with excellent chemo- and stereoselectivity. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Synthetic Route of C12H14O3).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Synthetic Route of C12H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Interaction of Gold Acetylides with Gold(I) or Silver(I) Cations was written by Jasikova, Lucie;Roithova, Jana. And the article was included in Organometallics in 2013.Application of 17920-23-9 This article mentions the following:

Structures and properties of complexes between (trimethylphosphino)gold acetylides and another (trimethylphosphino)gold cation were studied in the light of the possible dual activation reaction mode in Au catalysis. Ag salts are often used as cocatalysts in Au catalysis; therefore, also mixed complexes of acetylides with (trimethylphosphino)Au(I) and Ag(I) cations were studied. Energy-resolved collision-induced dissociation experiments, ion spectroscopy, and d. functional theory calculations show that the Au and Ag cations preferentially coordinate to the Au acetylides rather than to neutral C椤氬挵 triple bonds in diyne-type substrates. The effect of the binding of two metal cations to acetylides with respect to nucleophilic additions is discussed. In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Application of 17920-23-9).

Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Application of 17920-23-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ethanol metabolism in guinea pig: ethanol oxidation and its effect on NAD/NADH ratios, oxygen consumption, and ketogenesis in isolated hepatocytes of fed and fasted animals was written by Zahlten, Rainer N.;Nejtek, Michael E.;Jacobsen, Jan. C.. And the article was included in Archives of Biochemistry and Biophysics in 1982.HPLC of Formula: 1190-39-2 This article mentions the following:

EtOH [64-17-5]-induced decrease of the mitochondrial NAD鑱借伣[53-84-9]/NADH鑱借伣[58-68-4] ratio was prevented by the addition of 4-methylpyrazole鑱借伣[7554-65-6]. In 48-h hepatocytes, endogenous ketogenesis was enhanced by 84%. Although EtOH did not further stimulate endogenous ketogenesis, it did increase ketogenesis in the presence of octanoate鑱借伣[74-81-7] or oleate鑱借伣[112-80-1]. This effect was almost completely prevented by 4-methylpyrazole. Also, the malic鑱?em>acid鑱借伣[6915-15-7]–aspartate鑱借伣[56-84-8] shuttle was the predominant H transport system during EtOH oxidation in guinea pig liver and a quant. important role of peroxidatic oxidation of EtOH by catalase鑱借伣[9001-05-2] in liver was not supported. Thus, the syndrome of alc. ketoacidosis may be due, at least partially, to the addnl. stimulation of ketogenesis by or from EtOH during fatty acid oxidation in the fasting state. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2HPLC of Formula: 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is 绾?valerolactone.HPLC of Formula: 1190-39-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Strain-Release Driven Spirocyclization of Azabicyclo[1.1.0]butyl Ketones was written by Tyler, Jasper L.;Noble, Adam;Aggarwal, Varinder K.. And the article was included in Angewandte Chemie, International Edition in 2021.HPLC of Formula: 15399-05-0 This article mentions the following:

Due to their intrinsic rigidity, three-dimensionality and structural novelty, spirocyclic mols. have become increasingly sought-after moieties in drug discovery. Herein, we report a strain-release driven synthesis of azetidine-containing spirocycles by harnessing the inherent ring strain of the azabicyclo[1.1.0]butane (ABB) fragment. Novel ABB-ketone precursors bearing silyl-protected alcs. were synthesized in a single step and shown to engage in electrophile-induced spirocyclization-desilylation reactions. Primary, secondary and tertiary silyl ethers were effectively transformed into a library of new spiro-azetidines, with a range of substituents and ring sizes. In addition, the products are generated with synthetically useful ketone and protected-amine functional groups, which provides the potential for further elaboration and for this chem. to be utilized in the rapid assembly of medicinally relevant compounds In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0HPLC of Formula: 15399-05-0).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120鎺?C閳ユ弲閳ユ彊 and O閳ユ弲閳ユ彊 angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C閳ユ彊閳ユ弲 bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. HPLC of Formula: 15399-05-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Impact of a novel probiotic Lactobacillus strain isolated from the bee gut on GABA content, antioxidant activity, and potential cytotoxic activity against HT-29 cell line of rice bran was written by Ghamry, Mohamed;Ghazal, Ahmed Fathy;Al-Maqtqri, Qais Ali;Li, Li;Zhao, Wei. And the article was included in Journal of Food Science and Technology (New Delhi, India) in 2022.COA of Formula: C6H10O2 This article mentions the following:

Rice bran was fermented with Lactobacillus apis, isolated from the bee gut as a novel probiotic strain, and Saccharomyces cerevisiae to investigate the relationship between its metabolites and antioxidant activity, nutraceutical value, and cytotoxic activity against the HT-29 cell line. The findings showed that L. apis improved the antioxidant activity (DPPH of 37.73%) and antioxidant capacity (ABTS of 37.62 mg Trolox/g,), as well as, hydroxyl radical-scavenging activity (91.55%) of rice bran compared to S. cerevisiae. The metabolic anal. of volatile compounds revealed an increase of alcs. and lactones in the samples fermented with S. cerevisiae. While the samples fermented with L. apis displayed an increase of ketones, esters, and thiazoles. On the other hand, L. apis and S. cerevisiae exhibited a significant ability to increase 绾?aminobutyric acid during different fermentation times. Compared with non-fermented samples (18.54%), L. apis increased the cytotoxic activity of rice bran against the HT-29 cell line to 34.17%, and S. cerevisiae to 31.34%. These results suggest that the fermentation of rice bran with S. cerevisiae and L. apis provides a promising strategy to improve the antioxidant activity and nutraceuticals of rice bran, and a potential source for plant-based pharmaceutical products. In the experiment, the researchers used many compounds, for example, 5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7COA of Formula: C6H10O2).

5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120鎺?C閳ユ弲閳ユ彊 and O閳ユ弲閳ユ彊 angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C閳ユ彊閳ユ弲 bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. COA of Formula: C6H10O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Changes in volatile flavor compounds of peppers during hot air drying process based on headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS) was written by Ge, Shuai;Chen, Yuyu;Ding, Shenghua;Zhou, Hui;Jiang, Liwen;Yi, Youjin;Deng, Fangming;Wang, Rongrong. And the article was included in Journal of the Science of Food and Agriculture in 2020.Synthetic Route of C6H12O2 This article mentions the following:

BACKGROUND : Flavor plays a critical role in defining sensory and consumer acceptance of dried pepper, and it can be affected by temperature and moisture content during hot air drying (HAD). Thus, headspace-gas chromatog.-ion mobility spectrometry (HS-GC-IMS) was used to analyze changes in volatile compounds of pepper during the HAD process with different drying temperatures RESULTS : A total of 45 volatile flavor compounds were identified, including 11 esters, 11 aldehydes, nine alcs., five ketones, three furans, three acids, two pyrazines, and one ether. The results showed that with the loss of moisture during drying, aldehydes and alcs. decreased, esters initially increased and then decreased. However, Pr acetate, 2,3-butanediol, 2-acetylfuran, and 2-methylpyrazine increased. Moreover, drying temperature was closely related to the change of volatile flavor compounds Aldehydes, alcs., and some other volatile flavor compounds (Me salicylate, Et acetate, 2-methylpyrazine, di-Pr disulfide) decreased with an increase of temperature (60-80鎺矯) at the same moisture content, while high temperature could promote the formation of Et octanoate, Me octanoate, benzaldehyde, furfurol, acetal, 5-methylfurfural, and 2-acetylfuran. Based on principal components anal. and heat map clustering anal., peppers dried at 70 or 80鎺矯 presented similar composition, and the loss of volatile flavor compounds was more than samples died at 60鎺矯 during the HAD process. CONCLUSION : Overall, the flavor quality of peppers dried at 60鎺矯 was better than that of other treatments during the HAD process. HS-GC-IMS was a reliable and effective means of analyzing volatile flavor compounds in peppers during the drying process. In the experiment, the researchers used many compounds, for example, Methyl2-methylbutyrate (cas: 868-57-5Synthetic Route of C6H12O2).

Methyl2-methylbutyrate (cas: 868-57-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Synthetic Route of C6H12O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics