Improved synthesis of thiophene-2-acetic acid was written by Zhou, Jianmin;Tan, Liquan;Yu, Mei;Lin, Rihui;Huang, Min. And the article was included in Jingxi Shiyou Huagong in 2012.Formula: C7H8O2S This article mentions the following:
Influence of different catalysts on acylation reaction of thiophene using thiophene and acetic anhydride as starting materials was reported. With 2-acetyl thiophene (I) as model substrate, effects of solvents and phase-transfer catalysts on oxidation rearrangement of the intermediate were studied. The oxidation rearrangement product 2-thienyl acetate (II) was formed using H3PW12O40/SiO2 and PEG-400 as the co-catalysts in chloroform. II was hydrolyzed to 2-thiophene acetic acid (III) with the yield of 66.8% after recrystallization The structure of III was confirmed by 1H NMR and IR. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Formula: C7H8O2S).
Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Formula: C7H8O2S
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics