Dehydrogenative alcohol coupling and one-pot cross metathesis/dehydrogenative coupling reactions of alcohols using Hoveyda-Grubbs catalysts was written by Ozer, Halenur;Arslan, Dilan;Ozturk, Bengi Ozgun. And the article was included in New Journal of Chemistry in 2021.Safety of Isopentyl 3-methylbutanoate This article mentions the following:
In this study, in situ formed ruthenium hydride species that were generated from Grubbs type catalysts are used as efficient catalysts for dehydrogenative alc. coupling and sequential cross-metathesis/dehydrogenative coupling reactions. The selectivity of Grubbs first generation catalysts (G1, I) in dehydrogenative alc. coupling reactions can be tuned for the ester (octyl octanoate) formation in the presence of weak bases, while the selectivity can be switched to the 灏?alkylated alc. (2-hexyyl-1-decanol) formation using strong bases. The performance of Hoveyda-Grubbs 2nd generation catalyst (HG2) was improved in the presence of tricyclohexylphosphine for the selective synthesis of ester derivatives RC(O)OR1 (R = heptyl, Ph, dec-9-en-1-yl, etc.; R1 = H, octyl, Bn, etc.) and with 绾?butyrolactone weak and strong bases in quant. yields. Allyl alc. was used as self and cross-metathesis substrate for the HG2 catalyzed sequential cross-metathesis/dehydrogenative alc. coupling reactions to obtain 绾?butyrolactone and long-chain ester derivatives in quant. yields. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Safety of Isopentyl 3-methylbutanoate).
Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Safety of Isopentyl 3-methylbutanoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics