Cobalt-Catalyzed Desymmetric Isomerization of Exocyclic Olefins was written by Liu, Xufang;Rong, Xianle;Liu, Shihan;Lan, Yu;Liu, Qiang. And the article was included in Journal of the American Chemical Society in 2021.Electric Literature of C10H16O2 This article mentions the following:
Chiral cyclic olefins, 1-methylcyclohexenes, are versatile building blocks for the synthesis of pharmaceuticals and natural products. Despite the prevalence of these structural motifs, the development of efficient synthetic methods remains an unmet challenge. Herein the authors report a novel desym. isomerization of exocyclic olefins using a series of newly designed chiral cobalt catalysts, which enables a straightforward construction of chiral 1-methylcyclohexenes with diversified functionalities. The synthetic utility of this methodol. is highlighted by a concise and enantioselective synthesis of a natural product, 灏?bisabolene. The versatility of the reaction products is further demonstrated by multifarious derivatization. In the experiment, the researchers used many compounds, for example, Ethyl 4-methylenecyclohexanecarboxylate (cas: 145576-28-9Electric Literature of C10H16O2).
Ethyl 4-methylenecyclohexanecarboxylate (cas: 145576-28-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Electric Literature of C10H16O2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics