Synthesis and conversions of some 浼?hydroxyisobutyric acid esters was written by Kuz’michev, O. V.;Ustavshchikov, B. F.;Farberov, M. I.. And the article was included in Zhurnal Organicheskoi Khimii in 1968.Computed Properties of C11H14O3 This article mentions the following:
Reaction of Me2C(OH)CO2Na (I) with organic halides gave esters Me2C(OH)CO2R (II), which on dehydration gave H2C:CMeCO2R (III), of possible interest as polymerization monomers. Preparation of II was carried out either by heating the reagents in HCONMe2 or by fusing them together. Dehydration was done by heating II, containing 1-5% Cu-hydroquinone complex (a polymerization inhibitor) at 60-80鎺?in C6H6, PhMe, or xylene with PCl5. The following II and III were prepared (R, % yield, b.p./mm., n20D, and d20 of II and % yield, b.p./mm., n20D, and d20 of III given): H2C:CHCH2, 99.0, 166鎺?760, 1.4311, 1.0040, 40.0, 141鎺?760, 1.4330, 0.9300; H2C:CMeCH2, 88.0, 179鎺?760, 1.4338, 0.9870, 21.0, 70鎺?25, 1.4386, 0.9250; PhCH2, 84.5, 125鎺?10, 1.5010, 1.0860, 16.5, 236鎺?760, 1.5145, 1.0480; 2,4-Me2C6H3CH2, 97.0, 146鎺?5, 1.5051, 1.0650, 23.0, 115鎺?2, 1.5130, 1.0230; p-PhOC6H4CH2, 97.0, 173-5鎺?2, 1.5540, 1.1700, 16.5, 138鎺?1, 1.5760, 1.1589. Reaction of 1,5-bis(chloromethyl)-2,4-dimethylbenzene or (p-ClCH2C6H4)2O with I gave 99.0% 1,5-bis(浼?hydroxyisobutyryloxymethyl)-2,4-dimethylbenzene, m. 73.5, and 99.0% p-Me2C(OH)CO2CH2C6H4)2O, b1.5 220鎺? n20D 1.5470, d20 1.2190, which were dehydrated to give 31.5% 1,5-bis(methacryloxymethyl)-2,4-dimethylbenzene, b1 140-5鎺? n20D 1.5336, d20 1.1609, and 40.0% (p-H2C:CHCO2CH2C6H4)2O, b1 180鎺? n20D 1.5695, d20 1.1900. Passage of II vapors over a Ca phosphate catalyst at high temperature gave simultaneous dehydration and hydrolysis to H2C:CMeCO2H and the corresponding alcs. or dialcs. In the experiment, the researchers used many compounds, for example, Benzyl 2-hydroxy-2-methylpropanoate (cas: 19444-23-6Computed Properties of C11H14O3).
Benzyl 2-hydroxy-2-methylpropanoate (cas: 19444-23-6) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Computed Properties of C11H14O3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics