Comparative study of three Achillea essential oils from eastern part of Turkey and their biological activities was written by Demirci, Betul;Baser, K. Husnu Can;Aytac, Zeki;Khan, Shabana I.;Jacob, Melissa R.;Tabanca, Nurhayat. And the article was included in Records of Natural Products in 2018.Product Details of 659-70-1 This article mentions the following:
Essential oils obtained by hydrodistillation were analyzed both by gas chromatog. (GC) and gas chromatog.-mass spectrometry (GC-MS). The main constituents found in Achillea oil were as follows: A. filipendulina Lam.: 43.8% santolina alc., 14.5% 1,8-cineole and 12.5% cis-chrysanthenyl acetate; A. magnifica Hiemerl ex Hub.-Mor.: 27.5% linalool, 5.8% spathulenol, 5.5% terpinen-4-ol, 4.7% 浼?terpineol and 4.7% 灏?eudesmol; A. tenuifolia Lam.: 12.4% artemisia ketone, 9.9% p-cymene, 7.1% camphor, 5.9% terpinen-4-ol, 4.7% caryophyllene oxide and 4.5% 浼?pinene. Furthermore, the Achillea essential oils were evaluated for antimalarial and antimicrobial activities. A. magnifica and A. filipendulina oils showed strong antimalarial activity against both chloroquine sensitive D6 (IC50= 1.2 and 0.68 娓璯/mL) and chloroquine resistant W2 (IC50= 1.1 and 0.9 娓璯/mL) strains of Plasmodium falciparum without any cytotoxicity to mammalian cells up to IC50=47.6 娓璯/mL against Vero cells whereas A. tenuifolia oil showed no antimalarial activity up to a concentration of 20 mg/mL. All three Achillea oils showed no antibacterial activity against human pathogenic bacteria up to a concentration of 200 娓璯/mL. A. tenuifolia and A. magnifica oils demonstrated mild antifungal activity against Cryptococcus neoformans (IC50= 45, 20 and 15 娓璯/mL, resp.). In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Product Details of 659-70-1).
Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Product Details of 659-70-1
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics