Three-component coupling using arynes and DMF: straightforward access to coumarins via ortho-quinone methides was written by Yoshida, Hiroto;Ito, Yu;Ohshita, Joji. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2011.SDS of cas: 1190-39-2 This article mentions the following:
ortho-Quinone methides, arising from a formal [2+2] cycloaddition between arynes and DMF, were found to facilely undergo a [4+2] cycloaddition with ester enolates or ketenimine anions to produce diverse coumarins in a straightforward manner. E.g., coumarin derivative I was prepared with 79% yield by reacting CH2(CO2Et)2 and F3CSO2O-2-C6H4SiMe3 with Me2NCHO using KF at 80°. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2SDS of cas: 1190-39-2).
malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.SDS of cas: 1190-39-2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics