Month: January 2023

Transmission of polar effects through aromatic systems. III. Hammett σ-constants was written by Norman, R. O. C.;Radda, G. K.;Brimacombe, D. A.;Ralph, P. D.;Smith, E. M.. And the article was included in Journal of the Chemical Society in 1961.Synthetic Route of C10H11FO2 This article mentions the following:

Hydrolysis of Et phenylacetate (I) and nine monosubstituted derivatives in aqueous Me₂CO at 25° were measured. The results supported the theory of van Bekkum, Verkade, and Wepster (CA 54, 16407g) that mesomeric p-interaction between substituent and functional center may affect the σ-value of a substituent. Variations in σ-values arising from the polar effect of the substituent on the resonance interaction of the functional center with the aromatic nucleus were noted. An improved method of obtaining σ-values was proposed in which use was made only of those reaction series where resonance interaction between the functional center and the aromatic ring was precluded. Substituted phenylacetic acids were prepared by known methods and converted into their Et esters. Liquid esters were purified by fractional distillation and the solid esters recrystallized from ligroine. The following phenylacetic acids and their Et esters were obtained (substituent, m.p. of acid, m.p. of Et ester, b.p./mm. of Et ester given): H, -, -, 227°/758; m-Me, 62°, -, 122-3°/18; m-NO₂, 118-20°, 11.5-12.5°, 127-35°/0.25; p-Me, 94°, -, 134-5°/25; p-OMe, 85-6°, -, 143-4°/11; p-F, 84.5°, 34°, 128-30°/31; p-Cl, -, 33-3.5°, -; p-Br, -, 31.0-1.5°, -; p-COMe, -, 62-3°, -; p-NO₂, -, 63°, -. The procedure for rate measurements was that described by Tommila and Hinshelwood (CA 33, 1199⁶). Atm. CO₂ was excluded by alkali solutions and these were restandardized frequently. Initial concentrations of alkali and ester were equal and the extent of hydrolysis was studied from 10-80% completion. Each reaction obeyed 2nd order kinetics. The following rate constants (l. mole^-1sec.^-1) for the alk. hydrolysis of Et phenylacetates at 25° were obtained (substituent, and 10²k given): II, 4.40; m-Me, 3.58; p-Me, 3.18; p-OMe, 3.93; p-F, 6.96; p-Cl, 9.71; p-Br, 10.10; p-COMe, 13.0; m-NO₂, 18.4; p-NO₂, 26.2. The following σⁿ and σ_G values were obtained (substituent, σⁿ, and σ_G given): p-Me, -0.129, -0.129; m-Me, -0.069, -0.105; p-OMe, -0.111, -0.097; p-F, 0.168, 0.143; p-Cl, 0.238, 0.256; p-Br, 0.265, 0.281; m-Cl, 0.373, 0.334; m-NO₂, 0.710, 0.576; p-NO₂, 0.778, 0.708. The σ_G and ρ values were obtained from the following reactions (reaction, solvent, temperature, ρ, s, r, n given): ArCH₂CO₂Et + OH^–, 60% Me₂CO, 25°, 1.069, 0.029, 0.996, 8; ArCH₂CO₂Et + OH^–, 85.4% alc., 24.8, 1.168, 0.021, 0.998, 5; ArCH₂CO₂H (pK_a), H₂O, 25°, 0.612, 0.027, 0.989, 8; ArCH₂OHc + OH^-1, 56% Me₂CO, 25°, 0.894, 0.019, 0.998, 8; ArCH₂NHAc + Cl₂, 40% AcOH, 18, -1.256, 0.049, 0.987, 5. In the experiment, the researchers used many compounds, for example, Ethyl 2-(4-fluorophenyl)acetate (cas: 587-88-2Synthetic Route of C10H11FO2).

Ethyl 2-(4-fluorophenyl)acetate (cas: 587-88-2) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Synthetic Route of C10H11FO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An approach to classifying occupational exposures to endocrine disrupting chemicals by sex hormone function using an expert judgment process was written by Prichystalova, R.;Caron-Beaudoin, E.;Richardson, L.;Dirkx, E.;Amadou, A.;Zavodna, T.;Cihak, R.;Cogliano, V.;Hynes, J.;Pelland-St-Pierre, L.;Verner, M. A.;van Tongeren, M.;Ho, V.. And the article was included in Journal of Exposure Science & Environmental Epidemiology in 2021.Reference of 84-61-7 This article mentions the following:

Endocrine disrupting chems. (EDCs) are exogenous substances that interfere with the endocrine system and cause adverse effects. We aimed to classify the effects of 24 known EDCs, prevalent in certain occupations, according to four modes of action (estrogenic, antiestrogenic, androgenic, and/or antiandrogenic). The state of the evidence of each EDC on sex hormone function was summarized and reviewed by an expert panel. For each mode of action, the experts evaluated the likelihood of endocrine disruption in five categories: “No”, “Unlikely”, “Possibly”, “Probably”, and “Yes”. Seven agents were categorized as “Yes,” or having strong evidence for their effects on sex hormone function (antiandrogenic: lead, arsenic, butylbenzyl phthalate, di-Bu phthalate, dicyclohexyl phthalate; estrogenic: nonylphenol, bisphenol A). Nine agents were categorized as “Probable,” or having probable evidence (antiandrogenic: bis(2-ethylhexyl)phthalate, nonylphenol, toluene, bisphenol A, diisononyl phthalate; androgenic: cadmium; estrogenic: copper, cadmium and; anti-estrogenic: lead). Two agents (arsenic, polychlorinated biphenyls) had opposing conclusions supporting both “probably” estrogenic and antiestrogenic effects. This synthesis will allow researchers to evaluate the health effects of selected EDCs with an added level of precision related to the mode of action. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Reference of 84-61-7).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Reference of 84-61-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recovery of wolframite from tungsten mine tailings by the combination of shaking table and flotation with a novel ”crab” structure sebacoyl hydroxamic acid was written by Huang, Zhiqiang;Zhang, Shiyong;Wang, Hongling;Liu, Rukuan;Cheng, Chen;Shuai, Shuyi;Hu, Yajing;Zeng, Yuhui;Yu, Xinyang;He, Guichun;Fu, Weng;Burov, Vladimir E.;Poilov, Vladimir Z.. And the article was included in Journal of Environmental Management in 2022.Recommanded Product: 106-79-6 This article mentions the following:

Tailings ponds for gangue mineral storage are widely recognized as a dangerous source of toxic minerals and heavy metal-bearing solution Therefore, recovering valuable minerals and critical elements from tailings is an important means to protect the environment in an economic way. Wolframite tailings usually contain a considerable amount of tungsten resources, but the presence of high content of kaolinite sludge makes it very difficult to recycle wolframite. Herein, a novel sebacoyl hydroxamic acid (SHA) was synthesized and introduced as a novel wolframite collector to effectively utilize wolframite tailings, and its collection performance was compared with that of benzohydroxamic acid (BHA). Micro-flotation tests showed that SHA could still obtain 80% wolframite recovery in the presence of kaolinite slimes. Bench-scale flotation tests indicated that SHA can effectively recover wolframite concentrate with 55.64% WO₃ grade and 75.28% WO₃ recovery from wolframite tailings by the combined shaking table-flotation process. Polarized light microscope observations showed that SHA could promote the formation of hydrophobic agglomerates of wolframite particles. These results show that SHA can be used as an efficient collector for disposing of wolframite tailings, and provide an important reference for the development of efficient and comprehensive utilization of tailings. In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Recommanded Product: 106-79-6).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Recommanded Product: 106-79-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Development of a multiclass method to quantify phthalates, pharmaceuticals, and personal care products in river water using ultra-high performance liquid chromatography coupled with quadrupole hybrid Orbitrap mass spectrometry was written by Rendedula, Deviprasad;Satyanarayana, Gubbala Naga Venkata;Asati, Ankita;Kaliyaperumal, Muralidharan;Mudiam, Mohana Krishna Reddy. And the article was included in Analytical Science Advances in 2021.Synthetic Route of C20H26O4 This article mentions the following:

Rationale : The organic micropollutants such as phthalates, pharmaceuticals, and personal care products (PPPCPs) enter the surface water through various routes. The aim of this study is to develop a sensitive and efficient method to identify and quantify 26 PPPCPs found in river water with acceptable accuracy and precision using a liquid chromatograph hyphenated with quadrupole hybrid Orbitrap mass spectrometry (Q-Orbitrap-MS) in a single chromatog. run. Method : The organic micropollutants were extracted from river water by solid-phase extraction (SPE) using hydrophilic-lipophilic balance sorbent and analyzed using an ultra-high performance liquid chromatograph (UHPLC) equipped with C18 stationary phase for chromatog. separation The targeted mass experiments were conducted in a Q-Orbitrap-MS system in pos. and neg. electrospray ionization mode. Results : The method was found to be linear in the concentration range of 1-125 ng/L with coefficient of determination lying in the range of 0.995-0.999. The method achieved limit of quantification in the range of 0.41-1.72 ng/L, and method recovery measured at three different concentrations was found to be in the range of 75-115%. Intra- and interday precision expressed as percent relative standard deviation was found to be <15%. Matrix effect was found to be in the range of 83.5-109.79%. The matrix match calibration was used for quantification of PPPCPs in river water sample. The method performance was evaluated by analyzing real samples collected from Ganga River, and the concentrations of 21 analytes were found to be in the range of 0.76-9.49 ng/L for pharmaceuticals, 1.49-8.67 ng/L for phthalates, and 0.9-7.58 ng/L for personal care products. Conclusions : The present method was found to be precise, sensitive, and rapid to determine 26 PPPCPs including phthalates in river water samples using SPE-UHPLC-Q-Orbitrap-MS. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Synthetic Route of C20H26O4).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Synthetic Route of C20H26O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Metal-free Catalytic Esterification of Aryl Alkyl Ketones with Alcohols via Free-radical Mediated C(sp³)-H Bond Oxygenation was written by Rammurthy, Banothu;Peraka, Swamy;Vasu, Amrutham;Krishna Sai, Gajula;Divya Rohini, Yennamaneni;Narender, Nama. And the article was included in Asian Journal of Organic Chemistry in 2021.Safety of Methyl 4-(2-hydroxyphenyl)butanoate This article mentions the following:

A novel metal-free catalytic one-pot approach has been developed for the esterification of aralkyl ketones RC(O)R¹ (R = Ph, naphth-2-yl, 2-bromophenyl, etc.; R¹ = Me, Et, benzyl) with alcs. R²OH (R² = Me, Et, i-Pr, n-Bu) under open-air atm. conditions. The inexpensive iodide/oxone reagent system allowed the cascade C(sp₃)-H bond oxygenation, selective C-C bond cleavage and esterification through the both radical and ionic pathways in a stepwise manner in one-pot. This mild, convenient and economically viable catalytic method tolerates the various functional groups to provide the corresponding alkyl benzoates RC(O)OR² in up to 98% yields with up to 99% selectivity. The efficiency and feasibility of scale-up of the present catalytic system were demonstrated with gram scale experiments (up to 10 g scale). In the experiment, the researchers used many compounds, for example, Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7Safety of Methyl 4-(2-hydroxyphenyl)butanoate).

Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Safety of Methyl 4-(2-hydroxyphenyl)butanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Compound-Specific Radiocarbon Analysis of Low Molecular Weight Dicarboxylic Acids in Ambient Aerosols Using Preparative Gas Chromatography: Method Development was written by Xu, Buqing;Cheng, Zhineng;Gustafsson, Orjan;Kawamura, Kimitaka;Jin, Biao;Zhu, Sanyuan;Tang, Tiangang;Zhang, Bolong;Li, Jun;Zhang, Gan. And the article was included in Environmental Science & Technology Letters in 2021.Recommanded Product: 1190-39-2 This article mentions the following:

Low mol. weight dicarboxylic acids constitute a large fraction of atm. organic aerosols, which impact atm. radiative forcing and hence Earth’s climate. Radiocarbon (¹⁴C) is a unique approach to unambiguously distinguishing the relative contributions of biomass-derived and fossil sources. Here, we developed a compound-specific radiocarbon anal. (CSRA) method for individual dicarboxylic acids in atm. particulates. Specifically, the method starts with a di-Bu ester derivatization technique, followed by separation and harvesting of single compounds employing a preparative capillary gas chromatog. in sufficient amounts for offline ¹⁴C measurement with accelerator mass spectrometry. The optimized preparative steps yielded recoveries of >60% and purities of >99% for target mols. The radiocarbon isotope compositions determined for reference standards taken through the entire method agree well with the original composition of each standard (R² = 0.9998). The applicability of the approach was demonstrated with ambient aerosol samples representing contrasting air mass regimes. This yielded two radically different yet system-consistent precursor sources. A min. size of 50μg of C of ambient dicarboxylic acids is needed for credible ¹⁴C measurement. The established method for CSRA of dicarboxylic acids demonstrates a new anal. dimension for studies of the source and evolution of atm. secondary organic aerosols. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Recommanded Product: 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 1190-39-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Studies on Cyclic Ketones. I was written by Ruhemann, Siegfried. And the article was included in Journal of the Chemical Society, Transactions in 1912.Product Details of 39163-39-8 This article mentions the following:

(CO₂Et)₂, NaOEt, and cyclopentanone, in Et₂O, gave ethyl cyclopentanone-2,5-dioxalate (I), deep yellow plates, m. 114-5°, and ethyl cyclopentanone-2-oxalate, yellow, b₁₅ 152-3°; needles, m. 26-7°. Both esters give deep red colors with FeCl₃. (I) gives a salt containing 2 mols. PhNHNH₂; colorless crystals. Cyclopentanone 2,5-dioxalic acid, yellow needles, m. 210° (decompose). (CO₂Et)₂, NaOEt, and 1-methyl-cyclopentane-3-one form only ethyl 1-methylcyclopentane-3-one-4-oxalate, pale yellow oil, b₁₄ 150°. Ethyl 1,3-dimethyl-Δ³-cyclohexene-5-one-6-oxalate (II), yellow needles, m. 132-3°. Acid, yellow prisms, m. 178° (decompose). Ethyl 1-hydrindone-2-oxalate (III), colorless needles, m. 74-5°. Salt with 1 PhNHNH₂, colorless crystals; unstable. Acid, faintly yellow needles, m. 214° (decompose). 5,6-Methylenedioxy-1-hydrindone-β-oxalic acid, using C₆H₆ as solvent and hydrolyzing the ester, which could not be purified, yellow needles, m. 260° (decompose). (III), heated in EtOH with PhNHNH₂.HCl and a little HCl, gave ethyl 1-phenyl-4,5-indenopyrazole-3-carboxylate (IV), pale yellow needles, m. 117-8°. Acid, needles, m. 250-1° (decompose); also prepared direct from the acid of (III). Silver salt, curdy, not attacked by light. Ethyl 4,5-indenopyrazole-3-carboxylate, colorless prisms, m. 174°. Acid, very slightly soluble, m. 310° (decompose). α-Hydrindone, NaOEt, and PhC îŒ?CCO₂Et yielded 6-phenyl-2,3-indeno-4-pyrone (V), needles, with 1 H₂O, m. 169° (for this reaction cf. C. A., 2, 1830, 3062). Chloroplatinate, plates. p-ONC₆H₄NMe₂ acts on 1,3-dimethyl-Δ³-cyclohexene-5-one and succinylosuccinic ester as an oxidizing agent, instead of condensing with these. An additional double bond is introduced into the cyclic ketone and the base is reduced to Me₂NC₆H₄N₂OC₆H₄NMe₂. In the experiment, the researchers used many compounds, for example, Ethyl 2-oxo-2-(2-oxocyclopentyl)acetate (cas: 39163-39-8Product Details of 39163-39-8).

Ethyl 2-oxo-2-(2-oxocyclopentyl)acetate (cas: 39163-39-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Product Details of 39163-39-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Oxyfunctionalization of Active Methylene Compounds Using Sodium Chlorite in Water was written by Kitanosono, Taku;Tani, Shinki;Kobayashi, Shu. And the article was included in Asian Journal of Organic Chemistry in 2018.Electric Literature of C11H20O4 This article mentions the following:

A methylene group inserted between proximal carbonyl groups underwent exclusive oxyfunctionalization with sodium chlorite in the presence of redox-inert Hf^IV in water. Although alternative routes involving prior α-functionalization can be executed under mild conditions, preparatively valuable oxidation methods that deliver high levels of both conversion and selectivity remain a prized goal from the standpoint of streamlining organic synthesis. Chlorine dioxide, which was generated as a yellowish gas during the reaction, is considered to be a bona fide oxidant against active methylene compounds The pivotal role of water was clear, given that the reaction was significantly retarded in both aqueous acetonitrile and ethanol, which can solubilize sodium chlorite. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Electric Literature of C11H20O4).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Electric Literature of C11H20O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Assessing the efficacy of chitosan nanomatrix incorporated with Cymbopogon citratus (DC.) Stapf essential oil against the food-borne molds and aflatoxin B₁ production in food system was written by Kumar, Akshay;Singh, Prem Pratap;Prakash, Bhanu. And the article was included in Pesticide Biochemistry and Physiology in 2022.Synthetic Route of C12H20O2 This article mentions the following:

The chitosan nanomatrix incorporated with Cymbopogon citratus essential oil (Ne-CcEO) possess enhanced efficacy against the food-borne molds and aflatoxin B1 production compared to free essential oil. The CcEO was encapsulated inside the chitosan nanomatrix with an average size 147.41 ± 16.18 nm and characterized by SEM, Fourier transforms IR spectroscopy, and X-ray diffraction assay. The encapsulation efficiency and loading capacity were ranged between (41.68-76.78%) and (5.3-8.80%). The biochem. and in-silico anal. results revealed the interference in functioning of membrane integrity, mitochondrial membrane potential, antioxidant defense, carbon source metabolism, methylglyoxal, and laeA gene in response to treatment of Ne-CcEO (0.5μl/mL). In addition, Ne-CcEO significantly protects the deterioration of Pennisetum glaucum (L.) R. Br. seed samples by A. flavus, aflatoxin B₁ contamination, and lipid peroxidation The Ne-CcEO could be considered as promising antifungal additives for the control of food-borne molds and aflatoxin B₁ contamination in the food system. In the experiment, the researchers used many compounds, for example, (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3Synthetic Route of C12H20O2).

(E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Synthetic Route of C12H20O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Rhodium(I)-Catalyzed Coupling-Cyclization of C=O Bonds with α-Diazoketones was written by Chen, Ziyang;Hu, Xinwei;Huang, Junmin;Zeng, Wei. And the article was included in Organic Letters in 2018.Formula: C12H14O3 This article mentions the following:

An unprecedented intermol. nucleophilic attack of C=X bonds (X = O and S) on the rhodium(I)-carbenes has been developed. This transformation allows for the coupling-cyclization of aroylamides with α-diazoketones and provides concise access to 2,4,5-trisubstituted 1,3-oxazoles, e.g., I, and 1,3-thiazoles, e.g., II, with a broad tolerance of functional groups. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Formula: C12H14O3).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Formula: C12H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics