Thiourea catalysed reduction of α-keto substituted acrylate compounds using Hantzsch ester as a reducing agent in water was written by Weng, Guanglin;Ma, Xiaobo;Fang, Dongmei;Tan, Ping;Wang, Lijiao;Yang, Linlin;Zhang, Yuanyuan;Qian, Shan;Wang, Zhouyu. And the article was included in RSC Advances in 2017.Related Products of 13669-10-8 This article mentions the following:
The first method for the reduction of α-keto substituted acrylate compounds RC(O)C(=CHR1)C(O)OR2 (R = Me, Ph, thiophen-2-yl, etc.; R1 = Et, 4-ClC6H4, furan-2-yl, etc.; R2 = Me, Et, i-Pr, t-Bu, Bn) by Hantzsch ester in water under the catalysis of thiourea, e.g., 1-(3,5-bis(trifluoromethyl)phenyl)-3-((1S,2R)-2-hydroxy-1,2-diphenylethyl)thiourea has been developed. The products RC(O)CH(CH2R1)C(O)OR2 were isolated in moderate to high yields (38-95%). These products are important intermediates in the synthesis of a series of natural products and other biol. active mols. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8Related Products of 13669-10-8).
Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Related Products of 13669-10-8
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics