Total synthesis and absolute configuration of the antibiotic oligopeptide (4S)-(+)-anthelvencin A and its 4R-(-) enantiomer was written by Lee, Moses;Coulter, Diane M.;Lown, J. William. And the article was included in Journal of Organic Chemistry in 1988.Safety of Ethyl 4-nitro-1H-pyrrole-2-carboxylate This article mentions the following:
The total syntheses of (4S)-(+)-anthelvencin A (I) (the naturally occurring isomer) and its (4R)-(-) enantiomer are described. The absolute configuration of natural anthelvencin A is thereby unambiguously assigned. The two enantiomers bind to duplex calf thymus DNA. In the experiment, the researchers used many compounds, for example, Ethyl 4-nitro-1H-pyrrole-2-carboxylate (cas: 5930-92-7Safety of Ethyl 4-nitro-1H-pyrrole-2-carboxylate).
Ethyl 4-nitro-1H-pyrrole-2-carboxylate (cas: 5930-92-7) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Safety of Ethyl 4-nitro-1H-pyrrole-2-carboxylate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics