Congiu, Cenzo et al. published their research in Journal of Medicinal Chemistry in 2005 | CAS: 14667-47-1

Methyl 2-aminonicotinate (cas: 14667-47-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.COA of Formula: C7H8N2O2

New Potential Anticancer Agents Based on the Anthranilic Acid Scaffold. Synthesis and Evaluation of Biological Activity was written by Congiu, Cenzo;Cocco, Maria Teresa;Lilliu, Valentina;Onnis, Valentina. And the article was included in Journal of Medicinal Chemistry in 2005.COA of Formula: C7H8N2O2 This article mentions the following:

The synthesis and anticancer activity of new compounds I (X = Y = CH, N; X = CH, Y = N; R = 2-MeOC6H4, 3-ClC6H4, 2,4,6-Cl3C6H2, 3-pyridyl, etc.), designed on the anthranilic acid scaffold, are reported. The antiproliferative activity was assayed by the National Cancer Institute in established in vitro and in vivo anticancer exptl. models. Structural variations based on the flufenamic acid motif afforded a series of (hetero)aryl esters of N-(2-(trifluoromethyl)pyridin-4-yl)anthranilic acid, which showed in vitro growth inhibitory properties against human tumor cell lines in nanomolar to low micromolar concentrations The pyridinyl ester I [X = CH; Y = N; R = 3-pyridyl; (II)] exhibited very potent in vitro antiproliferative efficacy, with a chemosensitive profile showing a number of GI50 values at concentrations lower than 10-7 M in the full panel of human tumor cell lines. II was also tested in vivo as a potential anticancer agent in the hollow fiber assay and in human tumor xenografts, showing moderate inhibitory properties. Anal. of biol. activities and the COMPARE procedure was utilized to support putative biochem. mechanisms implicated with the antiproliferative activity. In the experiment, the researchers used many compounds, for example, Methyl 2-aminonicotinate (cas: 14667-47-1COA of Formula: C7H8N2O2).

Methyl 2-aminonicotinate (cas: 14667-47-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.COA of Formula: C7H8N2O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics