Catalytic C-C coupling of diazo compounds with arylboronic acids: using surface modified sewage sludge as catalyst was written by Zhang, Zhipeng;Yu, Yang;Xie, Yuxing;Hughes, Timothy;Xu, Jun;Huang, Fei;Huang, He. And the article was included in Green Chemistry in 2020.Recommanded Product: 587-88-2 This article mentions the following:
A green, mild and efficient synthesis of diarylmethines I [R = Ac, Ph, 4-FC6H4, etc.; R1 = H, Ph, 3-pyridyl, etc.; R2 = Me, Et, Bn, etc.] using sewage sludge-derived carbonaceous materials (SW) by perchloric acid catalyzed coupling reactions between diazo compounds and arylboronic acids was developed. The reaction showed a high level of functional tolerance and a broad substrate scope. Furthermore, the highly selective 1,2-alkyl shift product chromenones II [R3 = H, 6-F, 6-Br; R4 = Me; R5 =Me, Et; R4R5 = (CH2)4, (CH2)2O(CH2)2, CH2C(Me)2(CH2)3] were furnished through the sterically demanding groups migration of diazo compounds (3-diazochromanone). The structures of 1,2-shift products were further confirmed by single-crystal X-ray anal. Significantly, the synthesis of the core structures of darifenacin (a clin. drug for overactive bladder syndrome, OAB) and diclofensine (a stimulant drug showing antidepressant and monoamine reuptake inhibitor activity) further demonstrated the efficacy and synthetic potential of this method. In the experiment, the researchers used many compounds, for example, Ethyl 2-(4-fluorophenyl)acetate (cas: 587-88-2Recommanded Product: 587-88-2).
Ethyl 2-(4-fluorophenyl)acetate (cas: 587-88-2) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: 587-88-2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics