Yang, Yuanshuai et al. published their research in Pharmazie in 2018 | CAS: 16413-26-6

3-Cyanophenylisocyanate (cas: 16413-26-6) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application In Synthesis of 3-Cyanophenylisocyanate

Synthesis and antibacterial evaluation of sulbactam derivatives against Acinetobacter baumannii was written by Yang, Yuanshuai;Tang, Sheng;Liu, Zhandong;Wang, Yanxiang;Pang, Jing;You, Xuefu;Song, Danoing;Li, Yinghong;Lu, Xi. And the article was included in Pharmazie in 2018.Application In Synthesis of 3-Cyanophenylisocyanate This article mentions the following:

Sulbactam, a known β-lactamase inhibitor, was found to own potent antimicrobial activity against Acinetobacter baumannii in clin. practice. Based on clin. evidence, a series of sulbactam derivatives I [R = H, NH2, 3-ClC6H4NHC(O)NH, etc.; R1 = H, Na, 2-O2NC6H4CH2, etc.] and II [R2 = H, Na, NHEt3; R3 = H, NH2, 3-MeC6H4NHC(O)NH, etc.] were designed, synthesized and evaluated for antibacterial activity against Acinetobacter baumannii, taking sulbactam as the lead. Among them, compound II [R2 = Na; R3 = H (III)] exhibited a good antibacterial activity against Acinetobacter baumannii with a MIC value of 4 μg/mL, slightly lower than that of sulbactam of 1 μg/mL. Especially, compound III displayed outstanding oral pharmacokinetic profiles with a maximum plasma concentration (Cmax) of 19.6 μg/mL and area under the curve (AUC) of 10.8 μgh/mL, much higher than those of sulbactam, and thus held the potential of being developed into an oral medication. These results provided the useful information for further structural modification and optimization of its kind, and compound III had been selected for the further investigation. In the experiment, the researchers used many compounds, for example, 3-Cyanophenylisocyanate (cas: 16413-26-6Application In Synthesis of 3-Cyanophenylisocyanate).

3-Cyanophenylisocyanate (cas: 16413-26-6) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application In Synthesis of 3-Cyanophenylisocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics