Reactions of ethyl cinnamates with arylacetamides was written by Shandala, Mowafak Y.;Al-Khashab, Abdul-Ilah Y.;Afzal, M.;Ahmad, Shakir S.. And the article was included in Journal of Heterocyclic Chemistry in 1980.Related Products of 584-74-7 This article mentions the following:
Treating 4-RC6H4CH:CHCO2Et (I; R = H, Cl, Me) with R1C6H4CH2CONH2 (II; R1 = H, 2-, 3-, 4-F, 3-Cl) gave the corresponding 2,6-diketo-3,4-diarylpiperidine III in addition to the corresponding 4-RC6H4CH:CHCONH2 and R1C6H4CH2CO2Et. The latter two are formed from the intermediates of the Claisen condensation of the reactants. Condensation of I (R = MeO) with II gave only p-methoxycinnamide in quant yields with the corresponding arylacetates. In the experiment, the researchers used many compounds, for example, Ethyl 2-fluorophenylacetate (cas: 584-74-7Related Products of 584-74-7).
Ethyl 2-fluorophenylacetate (cas: 584-74-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Related Products of 584-74-7
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics