Using a bio-inspired surface resonance plasmon electronic nose for fundamental research on human olfaction was written by Mantel, Marylou;Fournel, Arnaud;Staedle, Ines;Oelschlagel, Annegret;Carro, Jeanne;Dubreuil, Romain;Herrier, Cyril;Livache, Thierry;Haehner, Antje;Hummel, Thomas;Roy, Jean-Michel;Bensafi, Moustafa. And the article was included in Sensors and Actuators, B: Chemical in 2022.Formula: C9H10O3 This article mentions the following:
Electronic noses are artificial devices designed to detect and classify odors, used for many industrial applications but they can also be a tool for fundamental research on the chem. senses. Indeed, one major issue in research on olfaction is that the relationship between the structure of volatile olfactory compounds and the perception they evoke is still little understood. Acknowledging the importance of biol. in the equation, the present study offers a new way to approach to stimulus-percept problem in olfaction, 1/ by considering as stimulus the interaction between odorants and olfactory receptors and 2/ by extending the measure of percept and considering the issue of interindividual diversity. To this end, we used a bio-inspired surface resonance plasmon electronic nose (e-nose) and acquired response patterns for 20 representative odorants. We also collected perceptual ratings (on intensity, pleasantness, familiarity, edibility and irritation) and verbal description of the perceptual experience associated to these odorants in a sample of 74 individuals. Combining Principal Component Anal. and Dissimilarity Matrix Anal., we showed a relationship between the e-nose space and both measures of perception, but only for odorants eliciting homogenous responses among the subjects. This study thus shows the relevance of a bio-inspired e-nose as a model of olfactory receptors interactions for the study of natural olfaction. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxybenzoate (cas: 118-61-6Formula: C9H10O3).
Ethyl 2-hydroxybenzoate (cas: 118-61-6) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Formula: C9H10O3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics