Oxyfunctionalization of Active Methylene Compounds Using Sodium Chlorite in Water was written by Kitanosono, Taku;Tani, Shinki;Kobayashi, Shu. And the article was included in Asian Journal of Organic Chemistry in 2018.Electric Literature of C11H20O4 This article mentions the following:
A methylene group inserted between proximal carbonyl groups underwent exclusive oxyfunctionalization with sodium chlorite in the presence of redox-inert HfIV in water. Although alternative routes involving prior α-functionalization can be executed under mild conditions, preparatively valuable oxidation methods that deliver high levels of both conversion and selectivity remain a prized goal from the standpoint of streamlining organic synthesis. Chlorine dioxide, which was generated as a yellowish gas during the reaction, is considered to be a bona fide oxidant against active methylene compounds The pivotal role of water was clear, given that the reaction was significantly retarded in both aqueous acetonitrile and ethanol, which can solubilize sodium chlorite. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Electric Literature of C11H20O4).
malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Electric Literature of C11H20O4
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics