Derivatives of 1-methoxy-3-trimethylsilyloxy-1,3-butadiene for Diels-Alder reactions was written by Danishefsky, Samuel;Yan, Cheng-Feng;Singh, Rajendra K.;Gammill, Ronald B.;McCurry, Patrick M. Jr.;Fritsch, Nancy;Clardy, Jon. And the article was included in Journal of the American Chemical Society in 1979.Safety of Methyl 4-Hydroxy-2-methoxybenzoate This article mentions the following:
The preparation and Diels-Alder cycloadditions of the following highly functionalized dienes are described: (1) (E)-1-methoxy-2-methyl-3-trimethylsilyloxy-1,3-butadiene, (2) (E,Z)-1-methoxy-3-trimethylsilyloxy-4-methyl-1,3-butadiene, (3) (E,Z)-1-methoxy-2,4-dimethyl-3-trimethylsilyloxy-1,3-butadiene, (4) (E,Z)-1-methoxy-3-trimethylsilyloxy-4-phenylseleno-1,3-butadiene, and (5) 1,1-dimethoxy-3-trimethylsilyloxy-1,3-butadiene. The use of these dienes in Diels-Alder reactions enables rapid access to diversely functionalized aromatics, cyclohexenones, cyclohexadienones, and 3-methoxycyclohexenones. In the experiment, the researchers used many compounds, for example, Methyl 4-Hydroxy-2-methoxybenzoate (cas: 28478-46-8Safety of Methyl 4-Hydroxy-2-methoxybenzoate).
Methyl 4-Hydroxy-2-methoxybenzoate (cas: 28478-46-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Safety of Methyl 4-Hydroxy-2-methoxybenzoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics