(Pentamethylcyclopentadienyl)Iridium Dichloride Dimer {[IrCp*Cl2]2}: A Novel Efficient Catalyst for the Cycloisomerizations of Homopropargylic Diols and N-Tethered Enynes was written by Benedetti, Erica;Simonneau, Antoine;Hours, Alexandra;Amouri, Hani;Penoni, Andrea;Palmisano, Giovanni;Malacria, Max;Goddard, Jean-Philippe;Fensterbank, Louis. And the article was included in Advanced Synthesis & Catalysis in 2011.Synthetic Route of C10H14O4 This article mentions the following:
(Pentamethylcyclopentadienyl)iridium dichloride dimer {[IrCp*Cl2]2}-catalyzed hydroalkoxylation of bis-homopropargylic alcs. provides an efficient access to dioxabicyclo[2.2.1]ketals. The cycloisomerizations proceed under mild conditions, with low catalytic loadings and short reaction times. This new protocol involving an Ir(III) catalyst also promoted the cycloisomerization of nitrogen-tethered 1,6-enynes to give azabicyclo[4.1.0]heptenes, enhancing the synthetic potential of our method. In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Synthetic Route of C10H14O4).
Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Synthetic Route of C10H14O4
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics