Dichloroethylaluminum-catalyzed reactions of alkenes with electrophilic cyclopropanes. A new cyclopentane annelation reaction was written by Beal, Richard B.;Dombroski, Mark A.;Snider, Barry B.. And the article was included in Journal of Organic Chemistry in 1986.Recommanded Product: 10203-58-4 This article mentions the following:
Reactions of cyclopropanedicarboxylates I (R, R1 = H, Me) with alkenes and EtAlCl2 were studied. Treatment of 1,1-di-, tri-, and tetrasubstituted alkenes with I (R = R1 = Me) and 2 equiv of EtAlCl2 gives zwitterions which collapse to cyclopentanedicarboxylates in good to excellent yield. This reaction provides a general procedure for the annulation of cyclopentanes to alkenes. Thus, methylenecyclohexane and 1-methylcyclohexene reacted with I and EtAlCl2 to afford 98% spiro compound II and 60% bicyclic compound III, resp. The intermediate zwitterions undergo the 1,2-hydride and 1,2-Me shifts characteristic of carbocations, although these side reactions are generally minor. I (R = H, R1 = Me) reacts similarly with alkenes at the more substituted carbon to give 3-methylcyclopentane-1,1-dicarboxylates. I (R = R1 = Me) rearranges in the presence of EtAlCl2 to di-Et isobutylidenemalonate, which reacts with alkenes and is reduced by EtAlCl2. The intramol. Lewis acid-induced addition of alkenes to cyclopropanedicarboxylate esters occurs analogously. In the experiment, the researchers used many compounds, for example, Diethyl isobutylmalonate (cas: 10203-58-4Recommanded Product: 10203-58-4).
Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Recommanded Product: 10203-58-4
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics