Month: December 2022

Zhu, Enci published the artcileEffects of zinc isophthalate on the crystallization and crystal transformation behavior of polybutene alloy, Product Details of C42H63O3P, the publication is Journal of Polymer Research (2022), 29(1), 14, database is CAplus.

The slow crystallization rate and crystal transformation restrict the application of PB-A (PB blended with 2-3wt% polypropylene). This paper investigated the effects of zinc isophthalate (ZnIA) on the crystallization and crystal transformation behavior of PB-A by means of DSC, POM, XRD and Flash DSC. The results showed that addition of ZnIA raised the crystallization peak temperature from 71.1°C to 82.8°C and decreased the half crystallization time from 818 s to 160 s at the content of 0.2wt%. It also reduced the spherulites size dramatically according to the images of POM. The survey conducted by Flash DSC showed that the formation of amorphous phase was retarded by the addition of ZnIA as cooling rate increasing and as a result, the crystallinity of PB-A was raised from 50.0 to 56.1% with 0.2wt% ZnIA added. Moreover, the improvement on crystal transformation caused by ZnIA could be owing to the increase in crystallization temperature which leads to the enhancement of internal thermal stress and shortened nucleating process as well before the growth of form I. In conclusion, Znic Isophthalate is a kind of effective and multifunctional nucleating agent for PB-A and this study is beneficial to understand the mechanism of crystallization as well as the crystal transformation for PB-A.

Journal of Polymer Research published new progress about 31570-04-4. 31570-04-4 belongs to esters-buliding-blocks, auxiliary class Mono-phosphine Ligands, name is Tris(2,4-di-tert-butylphenyl) phosphite, and the molecular formula is C7H9BO3S, Product Details of C42H63O3P.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Shen, Yan published the artcileEffects of gallic acid alkyl esters and their combinations with other antioxidants on oxidative stability of DHA algae oil, Computed Properties of 121-79-9, the publication is Food Research International (2021), 110280, database is CAplus and MEDLINE.

The most effective composite antioxidants for DHA algae oil were optimized by combining the selected gallic acid (GA) alkyl ester with other commonly used antioxidants. Results of Rancimat induction time, peroxide value, thiobarbituric acid-reactive substances, and free radical generation indicated that octyl gallate (OG) was the best one in DHA algae oil among GA alkyl esters with various chain lengths. Therefore, OG was used to combine other antioxidants (antioxidant of bamboo leaves, rosemary extract, tea polyphenols, tea polyphenol palmitate (TPP), ascorbyl palmitate, vitamin E, phytic acid and phospholipid) for further improving the oxidative stability of DHA algae oil. The combination of OG + TPP showed the best antioxidant effect among the composite antioxidants of two and three components. Through optimization of mixture ratio, the combination of 53.20 mg/kg OG + 360 mg/kg TPP demonstrated the best antioxidant capacity, which prolonged the shelf life of DHA algae oil by 4.24 folds.

Food Research International published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C14H10O4S2, Computed Properties of 121-79-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zhang, Yueqi published the artcileAnalysis of volatile flavor compounds in blue cheese, COA of Formula: C20H40O2, the publication is Shipin Kexue (Beijing, China) (2015), 36(16), 132-136, database is CAplus.

The volatile flavor components of blue cheese were extracted by solid-phase micro extraction (SPME) or simultaneous distillation extraction (SDE), and analyzed by gas chromatog.-mass spectrometry (GC-MS). A total of 111 volatile compounds were identified in blue cheese, including 2 hydrocarbons, 6 aldehydes, 12 ketones, 20 acids, 49 esters, 13 alcs. and phenols, and 9 sulfur-containing compounds or nitrogen-containing compounds or heterocyclic compounds 2-Heptanone, 2-nonanone, butanoic acid, hexanoic acid, n-decanoic acid, decanoic acid Et ester, 3-(methylthio)-1-propanol, and 6-heptyltetrahydro-2H-pyran-2-one may have impacts on the flavor of blue cheese.

Shipin Kexue (Beijing, China) published new progress about 110-34-9. 110-34-9 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester, name is Isobutyl palmitate, and the molecular formula is C9H9F5Si, COA of Formula: C20H40O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Cooksey, John published the artcileThe nucleophilic addition of α-metallated 1,3-dioxanes to planar chiral cationic η³-allylmolybdenum complexes. Synthesis of (2E,5S,6R,7E)-6-methyl-8-phenylocta-2,7-dienoic acid methyl ester, a key component of the Cryptophycins, Application In Synthesis of 5205-11-8, the publication is Organic & Biomolecular Chemistry (2004), 2(12), 1719-1731, database is CAplus and MEDLINE.

Two adjacent stereogenic centers and a pendant alkene were constructed via nucleophilic addition of a 1,3-dioxan-4-ylcopper(I) reagent to a cationic η³-allylmolybdenum complex as part of a synthesis of (2E,5S,6R,7E)-5-hydroxy-6-methyl-8-phenylocta-2,7-dienoic acid Me ester (I), a key component of the Cryptophycins. Oxidative addition of Mo(CO)₄(THF)₂ to allyl benzoates provides an efficient synthesis of η³-allylmolybdenum(dicarbonyl) complexes.

Organic & Biomolecular Chemistry published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C12H14O2, Application In Synthesis of 5205-11-8.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Tominaga, Takatoshi published the artcileRole of Certain Volatile Thiols in the Bouquet of Aged Champagne Wines, Application In Synthesis of 19788-49-9, the publication is Journal of Agricultural and Food Chemistry (2003), 51(4), 1016-1020, database is CAplus and MEDLINE.

A method for the specific extraction of volatile thiols by use of p-hydroxymercuribenzoate has made it possible to identify certain flavor-active volatile thiols in Champagne wines. Benzenemethanethiol, 2-furanmethanethiol, and Et 3-mercaptopropionate were present in these wines at concentrations considerably higher than their perception thresholds. Their concentrations increased gradually in proportion to the bottle aging period and sharply as a result of disgorging. The contribution of these volatile thiols to the empyreumatic nuances of the bouquet of aged Champagne wines was demonstrated for the 1st time.

Journal of Agricultural and Food Chemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C7H12ClNO, Application In Synthesis of 19788-49-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Li, Nan published the artcileCobalt-Catalyzed Deprotection of Allyl Carboxylic Esters Induced by Hydrogen Atom Transfer, Category: esters-buliding-blocks, the publication is Organic Letters (2021), 23(21), 8460-8464, database is CAplus and MEDLINE.

A brief, efficient method has been developed for the removal of the allyl protecting group from allyl carboxylic esters RC(O)OCH₂CH=CH₂ (R = cyclohexyl, Ph, thiophen-2-yl, 2H-1,3-benzodioxol-5-yl, etc.) using a Co(II)/TBHP/(Me₂SiH)₂O catalytic system. This facile strategy displays excellent chemoselectivity, functional group tolerance, and high yields. This transformation probably occurs through the hydrogen atom transfer process, and a Co(III)-six-membered cyclic intermediate is recommended.

Organic Letters published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C9H8O4, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Subrahmanyam, Sreenath published the artcileOptimisation of experimental conditions for synthesis of high affinity MIP nanoparticles, Recommanded Product: Benzyl diethylcarbamodithioate, the publication is European Polymer Journal (2013), 49(1), 100-105, database is CAplus.

Molecularly imprinted nanoparticles were synthesized via iniferter polymerization in the presence of a chain terminator agent and at high monomer and template concentration The amount of initiator, chain terminator agent and UV irradiation time were optimized in order to achieve maximum yield of discrete nanoparticles without causing macrogelation of the polymerization mixture Resultant particles were then purified from unreacted monomers via gel permeation and characterized by size-exclusion chromatog., dynamic light scattering and electron microscopy. The affinity towards the target was verified via surface plasmon resonance on immobilized templates. The yield of nanoparticles obtained using this approach was 14%, a significant increase when compared with similar methods using high monomer concentration and UV initiation.

European Polymer Journal published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C6H6N2O, Recommanded Product: Benzyl diethylcarbamodithioate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Mijangos, Irene published the artcileMacroradical initiated polymerization of acrylic and methacrylic monomers, Name: Benzyl diethylcarbamodithioate, the publication is Journal of Separation Science (2009), 32(19), 3340-3346, database is CAplus and MEDLINE.

An approach has been developed for the grafting of monomers onto poly(trimethylolpropane trimethacrylate) (polyTRIM) particles using 2,2-di-Et dithiocarbamic acid benzyl ester (DDCABE) as an initiator. A set of polymers was prepared with this technique over different lengths of time and the kinetics of the reaction studied exptl. It was found that the grafting of initiator to the polymeric support followed a second order reaction, while the subsequent addition of monomers from solution into the polyTRIM macroradicals followed a first order reaction. The living nature of the iniferter modified macroradicals permits easy consecutive grafting of multiple polymeric layers, allowing straightforward functionalization of particles. However, the effectiveness of the grafted initiator decreased with each cycle of polymerization This technique can be used for a wide range of applications in anal. and biochem.

Journal of Separation Science published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, Name: Benzyl diethylcarbamodithioate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Nicholas, Jacqueline A published the artcileDimethyl fumarate is associated with lower rates of infection and lower infection-related healthcare costs when compared with ocrelizumab., Category: esters-buliding-blocks, the publication is Multiple sclerosis and related disorders (2022), 103921, database is MEDLINE.

BACKGROUND: Infections in people with multiple sclerosis (PwMS) may have a detrimental effect on disease progression, risk of hospitalization, and healthcare resource utilization (HRU). The infection risk and HRU costs may vary between disease-modifying therapies (DMTs); however, the individual risks and differences associated with DMTs are not well characterized. Some DMTs may increase the risk for infections in PwMS; however, previous studies have reported an intact humoral immune response in dimethyl fumarate (DMF)-treated patients. The objective was to compare infection-related HRU and healthcare costs (HCCs) between PwMS treated with DMF or ocrelizumab (OCR). METHODS: Eligible patients were identified from the Optum US claims database between April 2017 and September 2020 (DMF n = 1429; OCR n = 3170). Patients were followed from index date to first occurrence of: (1) end of study, (2) end of insurance eligibility, (3) discontinuation of index DMT, or (4) switch from index DMT to another DMT. Outcomes were annualized rate of infection encounters (defined as infection encounters [n] during follow-up window / days followed [n] × 365); annualized infection-related HCCs (defined as aggregated costs of infection encounters during follow-up window / days followed [n] × 365); location-specific infections, and overall infection-related events. Propensity score matching (PSM) 1:1 method was used; PS was calculated via logistic regression for probability of DMF treatment conditional on demographics and comorbidities. Mean differences (MD) were reported for infection encounter measures. RESULTS: After PSM, DMF and OCR cohorts (n = 1094 in each cohort) were balanced based on baseline characteristics (standardized MD of adjusted baseline characteristics <0.1). Mean (standard deviation) follow-up was 296 (244) days for DMF patients and 297 (243) for OCR patients. DMF patients experienced lower annualized rates of overall infection encounters vs OCR patients (MD -0.51 [95% confidence interval (CI): -0.92 to -0.11], p = 0.01). When stratified by type of infection encounter, DMF patients experienced significantly lower annualized rates of outpatient (MD [95% CI]: -0.44 [-0.80 to -0.08], p = 0.02) and inpatient/hospitalization infection encounters (-0.08 [-0.14 to -0.02], p<0.01) vs OCR patients. A trend towards a shorter duration of infection-related hospitalization in the DMF vs the OCR group was observed (MD [95% CI]: -2.20 [-4.73 to 0.26] days, p = 0.08). The most common infection types in both DMT groups were urinary tract infections, sepsis, and pneumonia. DMF patients experienced lower annualized infection-related HCCs (MD [95% CI]: -$3642 [-$6380 to -$904], p < 0.01) vs OCR patients, which were driven largely by infection-related hospitalization costs (-$3639 [-$6019 to -$1259], p < 0.01). CONCLUSION: DMF-treated patients PS-matched with OCR patients experienced lower annualized rates of infection encounters and lower infection-related HCCs.

Multiple sclerosis and related disorders published new progress about 624-49-7. 624-49-7 belongs to esters-buliding-blocks, auxiliary class Inhibitor,Natural product, name is Dimethyl fumarate, and the molecular formula is C6H8O4, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Il’in, Anton published the artcilePhosphine catalyzed addition of long-chain dialkyl phosphites to electron-deficient alkenes, SDS of cas: 617-52-7, the publication is Synthetic Communications (2020), 50(21), 3287-3297, database is CAplus.

Conjugate addition of the long chain dialkyl phosphites to electron-deficient alkenes under PBu₃ catalysis afforded the corresponding phosphonates in good yields in a short reaction time. Long chain alkyl groups in the phosphites were well tolerated in this transformation. The products of this reaction are of particular interest as components of lubrication oil composition

Synthetic Communications published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C7H10O4, SDS of cas: 617-52-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics