Month: December 2022

Kim, Young Been published the artcileCamouflage coating using photochromic microcapsules and epoxy resin, Formula: C15H20O6, the publication is Polymer (Korea) (2022), 46(2), 288-294, database is CAplus.

Using photochromism of a diarylethene, we demontrate an easy but highly effective coating method for a camouflage application. The photochromic ink is consisting of capsule type of photochromic pigments and UV curable epoxy resin, reversibly presenting colored pattern in response to UV light. The transmittance of the coatings was investigated based on concentrations of the photochromic microcapsules, we have found that 5 weight% of the microcapsules in epoxy resin is most appropriate for camouflage with background. Besides, in order to increase mech. stability of the coating, thin protective layer including acrylate chems. is further coated on the patterns. By taking advantage of bar-coating with various mask pattern, different patterns were successfully coated on various types of surfaces such as wood, glass, general concrete wall and even curved surfaces. Based on the coating method, camouflage application for an encryption quick response (QR) pattern was successfully demonstrated.

Polymer (Korea) published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C15H20O6, Formula: C15H20O6.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Tang, Xinde published the artcileSynthesis and property of photo- and temperature- dual-responsive amphiphilic block copolymers, Application In Synthesis of 135529-02-1, the publication is Advanced Materials Research (Zuerich, Switzerland) (2010), 47-51, database is CAplus.

Photo- and temperature-responsive amphiphilic ethylene glycol-N-isopropylacrylamide (NIPAM)-6-[4-(4-methoxyphenylazo)phenoxy]hexyl methacrylate (MAZO) block copolymer (I) was designed and synthesized by atom transfer radical polymerization (ATRP). The macroinitiator based on polyethylene glycol (PEG, M_n = 2000 Da) was utilized to initiate the copolymerization of NIPAM and MAZO. I combining photo-responsive moieties with thermal-responsive moieties, showed photo- and temperature-dual-responsive property, among of which, PNIPAM shows lower critical solution temperature (LCST) and PMAZO exhibits reversible trans-cis isomerization under UV/vis irradiation In selective solution they can form selective micro-tunnel with excellent controlled release, and can be used as drug carrier and controllable membrane.

Advanced Materials Research (Zuerich, Switzerland) published new progress about 135529-02-1. 135529-02-1 belongs to esters-buliding-blocks, auxiliary class azo,Alkenyl,Benzene,Ester,Ether, name is 6-(4-((4-Methoxyphenyl)diazenyl)phenoxy)hexyl methacrylate, and the molecular formula is C12H9NO, Application In Synthesis of 135529-02-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Yang, Chang Yeol published the artcileSex Pheromones and Reproductive Isolation of Three Species in Genus Adoxophyes, Computed Properties of 16974-11-1, the publication is Journal of Chemical Ecology (2009), 35(3), 342-348, database is CAplus and MEDLINE.

We tested differences in female pheromone production and male response in 3 species of the genus Adoxophyes in Korea. Females of all 3 species produced mixtures of (Z)-9-tetradecenyl acetate (Z9-14:OAc) and (Z)-11-tetradecenyl acetate (Z11-14:OAc) as major components but in quite different ratios. The ratio of Z9-14:OAc and Z11-14:OAc in pheromone gland extracts was estimated to be ∼100:200 for Adoxophyes honmai, 100:25 for Adoxophyes orana, and 100:4000 for Adoxophyes sp. Field tests showed that males of each species were preferentially attracted to the 2-component blends of Z9-14:OAc and Z11-14:OAc mimicking the blends found in pheromone gland extracts of conspecific females. The effects of minor components identified in gland extracts on trap catches varied with species. Addition of 10-methyldodecyl acetate (10me-12:OAc) or (E)-11-tetradecenyl acetate (E11-14:OAc) to the binary blend of Z9-14:OAc and Z11-14:OAc significantly increased captures of A. honmai males, whereas E11-14:OAc exhibited a strongly antagonistic effect on catches of Adoxophyes sp. males. Moreover, (Z)-9-tetradecen-1-ol (Z9-14:OH) or (Z)-11-tetradecen-1-ol (Z11-14:OH) added to the binary blends increased attraction of male A. orana but not A. honmai and Adoxophyes sp. males, suggesting that these minor components, in addition to the relative ratios of the 2 major components, play an important role in reproductive isolation between Adoxophyes species in the southern and midwestern Korea where these species occur sympatrically.

Journal of Chemical Ecology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C10H10O2, Computed Properties of 16974-11-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Rosen, Wen Qi published the artcileThe circadian rhythm of the sex-pheromone-mediated behavioral response in the turnip moth, Agrotis segetum, is not controlled at the peripheral level, Quality Control of 16974-11-1, the publication is Journal of Biological Rhythms (2003), 18(5), 402-408, database is CAplus and MEDLINE.

The pheromone-mediated upwind flight of male turnip moths was observed in a flight tunnel at different times of day under conditions of a light-dark (LD) cycle, constant darkness (DD), and a shifted photoperiod. Under both LD and DD conditions, a significantly larger number of males flew to the pheromone during both the scotophase and the subjective scotophase than during the photophase and the subjective photophase for 2 consecutive days. When 1-day-old moths were transferred to a shifted LD cycle with lights turned off 4 h earlier, male behavioral responses to the pheromone advanced in time accordingly by 4 h. This showed that male behavioral responses to the pheromone are under the control of an endogenous oscillator. To further examine the level at which the circadian rhythm of the male behavioral response is regulated, the authors tested the olfactory responses of male antennal receptors to pheromone stimuli by means of electroantennograms (EAG) at different times of day. No significant variation in the sensitivity of the male antennal response to the pheromone was observed in terms of time of day. The results suggest that circadian regulation of the rhythmic behavioral response to pheromones in the male Agrotis occurs at the central nervous system level.

Journal of Biological Rhythms published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Quality Control of 16974-11-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Rosnizam, Arif Naim published the artcilePalladium(II) complexes bearing N,O-bidentate Schiff base ligands: Experimental, in-silico, antibacterial, and catalytic properties, Category: esters-buliding-blocks, the publication is Journal of Molecular Structure (2022), 132821, database is CAplus.

Two N,O-bidentate ligands (1, 2), and their Pd(II) complexes, (1a, 2a) were synthesized and characterized via elemental anal., IR, ¹H and ¹³C NMR, magnetic moment and UV-Visible spectroscopy. Single crystal x-ray diffraction revealed that 1a crystallized as a monoclinic system in P2(1)/c space group, where two ligand 1 moieties coordinate to one palladium(II) center through imine N and phenolic O donor atoms in a bis-bidentate manner, manifesting in a square planar geometry. The exptl. spectral data of 1 and 1a were in good agreement with the calculated ones obtained in gas phase and polarizable continuum model (PCM) at the B3LYP/LANL2DZ level of theory. The exptl. spectroscopic and Z-matrix data were also well reproduced with high correlation coefficients The intercontact between 1a complex units was determined through Hirshfeld surface anal. and electrostatic potentials (ESP) maps, showing that the most predominant interactions were H^…H (53.4%), C^…H (25.3%) and O^…H (12.6%). 1 And 1a were screened in-vitro to evaluate their antibacterial activity against two Gram-pos. (S. aureus, S. haemolyticus) and two Gram-neg. (P. aeruginosa, S. sonnei) bacteria. The antibacterial results revealed that 1a exhibited slight activity against Gram-neg. bacteria, while the free ligand displayed no activity. The catalytic efficiency of 1a and 2a was evaluated in Mizoroki-Heck reaction of iodobenzene and Me acrylate, and Suzuki-Miyaura reaction of iodobenzene and phenylboronic acid. Both catalysts resulted in good conversion percentages with 1a showing a more superior performance.

Journal of Molecular Structure published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C10H10O2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Shibata, Makoto published the artcileTotal syntheses of patellamides, cytotoxic cyclic peptides from a marine tunicate, Recommanded Product: (R)-tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate, the publication is Tennen Yuki Kagobutsu Toronkai Koen Yoshishu (1985), 267-74, database is CAplus.

The structures of patellamides A, B, and C have been proposed to be cyclic peptides I, II, and III, resp. I and II were synthesized by solution methods, but these synthetic peptides were not identical with natural patellamides B and C. An inspection of evidences used for the originally assigned structures and a synthetic study on the partial hydrolyzate of patellamide B indicated that the structures of patellamides B and C could be reassigned as cyclic peptides IV and V, resp., having the reverse order of amino acid residues. This deduction was confirmed by the syntheses of revised structures IV and V, which were completely identical with natural patellamides B and C, resp. The structures of patellamide A was analogously revised as cyclic peptide VI by its synthesis.

Tennen Yuki Kagobutsu Toronkai Koen Yoshishu published new progress about 106391-88-2. 106391-88-2 belongs to esters-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Aldehyde, name is (R)-tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate, and the molecular formula is C8H6ClN, Recommanded Product: (R)-tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Unbehend, Melanie published the artcilePheromonal Divergence Between Two Strains of Spodoptera frugiperda, Related Products of esters-buliding-blocks, the publication is Journal of Chemical Ecology (2013), 39(3), 364-376, database is CAplus and MEDLINE.

Spodoptera frugiperda consists of 2 genetically and behaviorally different strains, the corn- and the rice-strain, which seem to be in the process of sympatric speciation. We investigated the role of strain-specific sexual communication as a prezygotic mating barrier between both strains by analyzing strain-specific variation in female pheromone composition of laboratory and field strains, and also male attraction in wind tunnel and field experiments Laboratory-reared and field-collected females from Florida exhibited strain-specific differences in their relative amount of (Z)-7-dodecenyl acetate (Z7-12:OAc) and (Z)-9-dodecenyl acetate (Z9-12:OAc). In wind tunnel assays, we did not find strain-specific attraction of males to females. However, in field experiments in Florida, we observed some differential attraction to synthetic pheromone blends. In a corn field, the corn-strain blend attracted more males of both strains than the rice-strain blend, but both blends were equally attractive in a grass field. Thus, habitat-specific volatiles seemed to influence male attraction to pheromones. In dose-response experiments, corn-strain males were more attracted to 2% Z7-12:OAc than other doses tested, while rice-strain males were attracted to a broader range of Z7-12:OAc (2-10%). The attraction of corn-strain males to the lowest dose of Z7-12:OAc corresponds to the production of this compound by females; corn-strain females produced significantly smaller amounts of Z7-12:OAc than rice-strain females. Although corn-strain individuals are more restricted in their production of and response to pheromones than rice-strain individuals, it seems that differences in sexual communication between corn- and rice-strain individuals are not strong enough to cause assortative mating.

Journal of Chemical Ecology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C8H6ClF3, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Unbehend, Melanie published the artcileGeographic variation in sexual attraction of Spodoptera frugiperda corn- and rice-strain males to pheromone lures, SDS of cas: 16974-11-1, the publication is PLoS One (2014), 9(2), e89255/1-e89255/11, 11 pp., database is CAplus and MEDLINE.

The corn- and rice-strains of Spodoptera frugiperda exhibit several genetic and behavioral differences and appear to be undergoing ecol. speciation in sympatry. Previous studies reported conflicting results when investigating male attraction to pheromone lures in different regions, but this could have been due to inter-strain and/or geog. differences. Therefore, we investigated whether corn- and rice-strain males differed in their response to different synthetic pheromone blends in different regions in North America, the Caribbean and South America. All trapped males were strain-typed by two strain-specific mitochondrial DNA markers. In the first experiment, we found a nearly similar response of corn- and rice-strain males to two different 4-component blends, resembling the corn- and rice-strain female blend we previously described from females in Florida. This response showed some geog. variation in fields in Canada, North Carolina, Florida, Puerto Rico, and South America (Peru, Argentina). In dose-response experiments with the critical secondary sex pheromone component (Z)-7-dodecenyl acetate (Z7-12:OAc), we found some strain-specific differences in male attraction. While the response to Z7-12:OAc varied geog. in the corn-strain, rice-strain males showed almost no variation. We also found that the minor compound (Z)-11-hexadecenyl acetate (Z11-16:OAc) did not increase attraction of both strains in Florida and of corn-strain males in Peru. In a fourth experiment, where we added the stereo-isomer of the critical sex pheromone component, (E)-7-dodecenyl acetate, to the major pheromone component (Z)-9-tetradecenyl acetate (Z9-14:OAc), we found that this compound was attractive to males in North Carolina, but not to males in Peru. Overall, our results suggest that both strains show rather geog. than strain-specific differences in their response to pheromone lures, and that regional sexual communication differences might cause geog. differentiation between populations.

PLoS One published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C4H11NO, SDS of cas: 16974-11-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Peter Ventura, Alejandra M. published the artcileSynthesis and antischistosomal activity of linker- and thiophene-modified biaryl alkyl carboxylic acid derivatives, Recommanded Product: 3-(Methoxycarbonyl)benzoic acid, the publication is Archiv der Pharmazie (Weinheim, Germany) (2021), 354(12), 2100259, database is CAplus and MEDLINE.

Schistosomiasis is a neglected tropical disease caused by blood flukes of the genus Schistosoma and causes severe morbidity in infected patients. In 2018, 290.8 million people required treatment, and 200,000 deaths are reported per yr. Treatment of this disease depends on a single drug, praziquantel (PZQ). However, in the past few years, reduced sensitivity of the parasites toward PZQ has been reported. Therefore, there is an urgent need for new drugs against this disease. In the past few years, we have focused on a new substance class called biaryl alkyl carboxylic acid derivatives, which showed promising antischistosomal activity in vitro. Structure-activity relationship (SAR) studies of the carboxylic acid moiety led to three promising carboxylic amides (morpholine, thiomorpholine, and Me sulfonyl piperazine) with an antischistosomal activity down to 10μM (morpholine derivative) and no cytotoxicity up to 100μM. Here, we show our continued work on this substance class. We investigated, in extended SAR studies, whether modification of the linker and the thiophene ring could improve the antischistosomal activity. We found that the exchange of the alkyl linker by a pentadienyl or benzyl linker was tolerated and led to similar antischistosomal effects, whereas the exchange of the thiophene ring was not tolerated. Our data suggest that the thiophene ring is important for the antischistosomal activity of this compound class.

Archiv der Pharmazie (Weinheim, Germany) published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C9H8O4, Recommanded Product: 3-(Methoxycarbonyl)benzoic acid.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Pontiki, Eleni published the artcileHistone deacetylase inhibitors (HDACIs). Structure-activity relationships: history and new QSAR perspectives, Synthetic Route of 122110-53-6, the publication is Medicinal Research Reviews (2012), 32(1), 1-165, database is CAplus and MEDLINE.

A review. Histone deacetylase (HDAC) inhibition is a recent, clin. validated therapeutic strategy for cancer treatment. HDAC inhibitors (HDACIs) block angiogenesis, arrest cell growth, and lead to differentiation and apoptosis in tumor cells. In this article, a survey of published quant. structure-activity relationships (QSARs) studies are presented and discussed in the hope of identifying the structural determinants for anticancer activity. Secondly a two-dimensional QSAR study was carried out on biol. results derived from various types of HDACIs and from different assays using the C-QSAR program of Biobyte. The QSAR anal. presented here is an attempt to organize the knowledge on the HDACIs with the purpose of designing new chem. entities with enhanced inhibitory potencies and to study the mechanism of action of the compounds This study revealed that lipophilicity is one of the most important determinants of activity. Addnl., steric factors such as the overall molar refractivity (CMR), molar volume (MgVol), the substituent’s molar refractivity (MR) (linear or parabola), or the sterimol parameters B₁ and L are important. Electronic parameters indicated as σ_p, are found to be present only in one case. © 2010 Wiley Periodicals, Inc. Med Res Rev 32:1-165, 2012.

Medicinal Research Reviews published new progress about 122110-53-6. 122110-53-6 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester,Inhibitor, name is (Pivaloyloxy)methyl butyrate, and the molecular formula is C10H18O4, Synthetic Route of 122110-53-6.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics