Month: December 2022

Matta, Khushi L. published the artcileSimple method for the synthesis of 2-acetamido-2-deoxy-β-D-galactopyranosides, Product Details of C14H19NO8, the publication is Carbohydrate Research (1973), 26(1), 215-18, database is CAplus.

Treatment of 2-acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-β-D- galactopyranose in CH2Cl2 with anhydrous FeCl3 gave 66% 2-methyl-(3,4,6-triO-acetyl-1,2-dideoxy-α-D-gal- actopyrano)-[2′ 1′:4,5]-2-oxazoline (I), which reacted readily with PhCH2OH and with 1,2,3-tri-O-benzoyl-α-D-galactose to give 65% benzyl β-glycoside derivative and 44% (1 → 6)-β-D-linked di- saccharide derivatives, resp.

Carbohydrate Research published new progress about 10378-06-0. 10378-06-0 belongs to esters-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Ester,Inhibitor,Inhibitor, name is (3aR,5R,6R,7R,7aR)-5-(Acetoxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]oxazole-6,7-diyl diacetate, and the molecular formula is C14H19NO8, Product Details of C14H19NO8.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Weis, Erik published the artcileLate-Stage Amination of Drug-Like Benzoic Acids: Access to Anilines and Drug Conjugates through Directed Iridium-Catalyzed C-H Activation, Formula: C9H8O4, the publication is Chemistry – A European Journal (2021), 27(72), 18188-18200, database is CAplus and MEDLINE.

The method presented herein enables the amination of a wide array of benzoic acids RC(O)OH (R = 2-fluorophenyl, naphthalen-1-yl, thiophen-2-yl, 2H-1,3-benzodioxol-4-yl, etc.) with high selectivity. The robustness of the system is manifested by the large number of functional groups tolerated, which allowed the amination of a diverse array of marketed drugs and drug-like mols. Furthermore, the introduction of a synthetic handle enabled expeditious access to targeted drug-delivery conjugates, e.g., I, PROTACs II, and probes for chem. biol. This rapid access to valuable analogs, combined with operational simplicity and applicability to high-throughput experimentation has the potential to aid and considerably accelerate drug discovery.

Chemistry – A European Journal published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C6H5F4NO3S, Formula: C9H8O4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Weis, Erik published the artcileIr^III-Catalyzed Selective ortho-Monoiodination of Benzoic Acids with Unbiased C-H Bonds, COA of Formula: C9H8O4, the publication is Chemistry – A European Journal (2020), 26(45), 10185-10190, database is CAplus and MEDLINE.

An iridium-catalyzed selective ortho-monoiodination of benzoic acids with two equivalent C-H bonds was presented. A wide range of electron-rich and electron-poor substrates underwent the reaction under mild conditions, with >20:1 mono/di selectivity. Importantly, the C-H iodination occurred selectively ortho to the carboxylic acid moiety in substrates bearing competing coordinating directing groups. The reaction was performed at room temperature and no inert atm. or exclusion of moisture was required. Mechanistic investigations revealed a substrate-dependent reversible C-H activation/protodemetalation step, a substrate-dependent turnover-limiting step and the crucial role of the AgI additive in the deactivation of the iodination product towards further reaction.

Chemistry – A European Journal published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C15H14BNO4S, COA of Formula: C9H8O4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Rabeschini, Gabriela published the artcileMeaningful Words in Crowd Noise: Searching for Volatiles Relevant to Carpenter Bees among the Diverse Scent Blends of Bee Flowers, Safety of Methyl 3-phenyl-2-propenoate, the publication is Journal of Chemical Ecology (2021), 47(4-5), 444-454, database is CAplus and MEDLINE.

Olfactory cues constitute one of the most important plant-pollinator communication channels. Specific chem. components can be associated with specific pollinator functional groups due to pollinator-mediated selection on flower volatile (FV) emission. Here, we used multivariate analyses of FV data to detect an association between FVs and the worldwide distributed pollinator group of the carpenter bees (Xylocopa spp.). We compiled FVs of 29 plant species: 9 pollinated by carpenter bees, 20 pollinated by other bee pollinator functional groups. We tested whether FV emission differed between these groups. To rule out any phylogenetic bias in our dataset, we tested FV emission for phylogenetic signal. Finally, using field assays, we tested the attractive function of two FVs found to be associated with carpenter bees. We found no significant multivariate difference between the two plant groups FVs. However, seven FVs (five apocarotenoid terpenoids, one long-chain alkane and one benzenoid) were significantly associated with carpenter bee pollination, thus being “predictor” compounds of pollination by this pollinator functional group. From those, β-ionone and (E)-Me cinnamate presented the highest indicator values and had their behavioral function assessed in field assays. Phylogenetic signal for FVs emission was weak, suggesting that their emission could result from pollinator-mediated selection. In field assays, the apocarotenoid β-ionone attracted carpenter bees, but also bees from other functional groups. The benzenoid (E)-Me cinnamate did not attract significant numbers of pollinators. Thus, β-ionone functions as a non-specific bee attractant, while apocarotenoid FVs emerge as consistent indicators of pollination by large food-foraging bees among bee-pollinated flowers.

Journal of Chemical Ecology published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C10H10O2, Safety of Methyl 3-phenyl-2-propenoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Fan, Wuhou published the artcileAchieving fast self-healing and reprocessing of supertough water-dispersed “living” supramolecular polymers containing dynamic ditelluride bonds under visible light, Related Products of esters-buliding-blocks, the publication is ACS Applied Materials & Interfaces (2020), 12(5), 6383-6395, database is CAplus and MEDLINE.

It is very challenging to achieve polymers that are mech. robust and fast self-healable at ambient conditions, which are highly desirable for smart materials of the next-generation. Herein, combining dynamic ditelluride bonds and 2-ureido-4[1H]-pyrimidinone (UPy) moieties in the main chains, a novel type of visible-light-induced self-healing water-dispersed supramol. polymers (DTe-WSPs) with outstanding healing properties were developed. The prepared DTe-WSPs emulsions showed excellent emulsion stability, and highly transparent DTe-WSPs films obtained from these emulsions exhibited much improved mech. properties and fast recoverability after the incorporation of UPy groups, owing to the phys. cross-links formed by quadruple hydrogen-bonded UPy moieties. Supertoughness (105.2 MJ m^-3) and fast self-healability under visible light (healing efficiency of 85.6% within 10 min) could be achieved simultaneously with the adjustment of the ditelluride content and the UPy content, and the toughness of our polymers is higher than those of the reported ambient temperature self-healable polymers. The visible-light-induced ditelluride metathesis is a predominant factor in the healing process of DTe-WSPs, and the ditelluride metathesis triggered by photothermy and hydrogen bonding could also afford the ultimate healing result. Meanwhile, DTe-WSPs can be reprocessed using visible light, providing a facile way to process polymers at mild conditions. To our surprise, the “living” DTe-WSPs exhibited the ability to initiate the polymerization of vinyl monomers under visible light, which is first reported for water-dispersed self-healing polymers. We considered the elaborated design philosophy, based on the readily available, clean, safe, and easily manipulated visible light, which can not only provide inspiration for preparing fast ambient temperature self-healing and reprocessing polymer materials with robust mech. properties but also develop a new macroinitiator to initiate the ambient temperature polymerization of vinyl monomers.

ACS Applied Materials & Interfaces published new progress about 517-23-7. 517-23-7 belongs to esters-buliding-blocks, auxiliary class Tetrahydrofuran,Ketone,Ester, name is 3-Acetyldihydrofuran-2(3H)-one, and the molecular formula is C6H8O3, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Yoshii, Daichi published the artcileGold nanoparticles on OMS-2 for heterogeneously catalyzed aerobic oxidative α,β-dehydrogenation of β-heteroatom-substituted ketones, Recommanded Product: Ethyl 3-(dimethylamino)acrylate, the publication is Chemical Communications (Cambridge, United Kingdom) (2016), 52(99), 14314-14317, database is CAplus and MEDLINE.

In the presence of Au nanoparticles supported on manganese oxide OMS-2 (Au/OMS-2), various kinds of β-heteroatom-substituted α,β-unsaturated ketones (heteroatom = N, O, S) can be synthesized through α,β-dehydrogenation of the corresponding saturated ketones using O₂ (in air) as the oxidant. The catalysis of Au/OMS-2 is truly heterogeneous, and the catalyst can be reused.

Chemical Communications (Cambridge, United Kingdom) published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C7H12ClNO, Recommanded Product: Ethyl 3-(dimethylamino)acrylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Liu, Xuesheng published the artcileIn situ Growth of UiO-66 with Its Particle Size Reduced by 90% into Porous Polyacrylate: Experiments and Applications, Application In Synthesis of 15625-89-5, the publication is Industrial & Engineering Chemistry Research (2022), 61(23), 7902-7910, database is CAplus.

In this study, we successfully synthesized a novel composite material UiO-66/polyacrylate (UiO/PA) by suspension polymerization and in situ growth of metal-organic frameworks (MOFs). Due to the control of heterogeneous nucleation and firm growth, nano-UiO-66 with a diameter of only 400 nm has been reduced by about 90%, resulting in lower transfer resistance, effective separation of photogenerated carriers, and more catalytic active sites exposed. Under visible light irradiation, UiO/PA with 48.7% loading can almost completely degrade rhodamine B (RhB) in 120 min and the corresponding degradation rate constant of RhB reached 0.0203 min^-1 from 0 min^-1. After easy filtration and five cycles, the degradation rate is still above 85%. This study can provide new insights into effectively improving the photocatalytic performance of MOFs.

Industrial & Engineering Chemistry Research published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C15H20O6, Application In Synthesis of 15625-89-5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zeng, Linwei published the artcilePhoto-induced synthesis of β-sulfonyl imides from carboxylic acids, Formula: C9H8O4, the publication is Chemical Communications (Cambridge, United Kingdom) (2021), 57(55), 6792-6795, database is CAplus and MEDLINE.

A photo-induced imidation process of carboxylic acids is described. Numerous carboxylic acids could convert to β-sulfonyl imides in the presence of N-sulfonyl ynamides under visible light irradiation Control experiments and mechanistic studies demonstrate that this imidation process involves a hydroacyloxylation/radical rearrangement cascade. This protocol represents a direct imidation method from carboxylic acids under mild conditions, with broad scope and high atom-economy.

Chemical Communications (Cambridge, United Kingdom) published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C7H5I2NO3, Formula: C9H8O4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Dai, Qianying published the artcileInvestigating volatile compounds’ contributions to the stale odour of green tea, Recommanded Product: Dimethyl adipate, the publication is International Journal of Food Science and Technology (2020), 55(4), 1606-1616, database is CAplus.

Summary : This study aimed to characterize the volatiles that contribute to stale odor of green tea. Volatiles were extracted using headspace solid-phase microextraction (HS-SPME) and analyzed using gas chromatog.-mass spectrometry (GC-MS) and gas chromatog.-olfactometry (GC-O). Results showed that a total of ninety-six volatiles were identified by GC-MS, in which forty-four volatiles were screened out based on Principal component anal. (PCA) and orthogonal projections to latent structures-discriminant anal. (OPLS-DA), and thirty-nine volatiles had a significant variation at the level of 0.05 by anal. of variance (ANOVA). From GC-O anal., fifty-four aromatic volatiles with strong aroma intensity (aroma intensity above 2) were perceived. Further investigation revealed that fifteen volatiles, including 1-octen-3-ol, benzyl alc., benzaldehyde, safranal, β-cyclocitral, (E,E)-3,5-octadien-2-one, (Z,E)-3,5-octadien-2-one, di-Me adipate, dihydroactinidiolide, β-ionone, α-ionone, geranyl acetone, phenylethyl alc., Me decanoate and α-terpineol were responsible for stale odor, besides the former nine compounds were only found in stored tea.

International Journal of Food Science and Technology published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C8H14O4, Recommanded Product: Dimethyl adipate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Liu, Binbin published the artcileWacker-Type Oxidation Using an Iron Catalyst and Ambient Air: Application to Late-Stage Oxidation of Complex Molecules, Product Details of C12H14O2, the publication is Angewandte Chemie, International Edition (2017), 56(41), 12712-12717, database is CAplus and MEDLINE.

A practical and general iron-catalyzed Wacker-type oxidation of olefins to ketones is presented, and it uses ambient air as the sole oxidant. The mild oxidation conditions enable exceptional functional-group tolerance, which has not been demonstrated for any other Wacker-type reaction to date. The inexpensive and nontoxic reagents [iron(II) chloride, polymethylhydrosiloxane, and air] can, therefore, also be employed to oxidize complex natural-product-derived and polyfunctionalized mols.

Angewandte Chemie, International Edition published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C12H14O2, Product Details of C12H14O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics