Month: December 2022

Synthesis and Evaluation of Partly Fluorinated Block Copolymers as MRI Imaging Agents was written by Peng, Hui;Blakey, Idriss;Dargaville, Bronwin;Rasoul, Firas;Rose, Stephen;Whittaker, Andrew K.. And the article was included in Biomacromolecules in 2009.HPLC of Formula: 3063-94-3 The following contents are mentioned in the article:

A series of well-defined diblock copolymers of acrylic acid with partially fluorinated acrylate and methacrylate monomers were synthesized using ATRP as potential ¹⁹F MRI imaging agents. The diblock copolymers could undergo spontaneous self-assembly in mixed and aqueous solvents to form stable micelles with a diameter from approx. 20-45 nm, having a fluorine-rich core that provides a strong signal for MRI examinations The observed MRI image intensities were related to the NMR longitudinal and transverse relaxation times, and were found to depend on polymer structure and method of micellization. Two distinct T₂ relaxation times were measured; on comparison of expected MRI image intensities with those observed exptl., methacrylate polymers show systematically lower signal intensity than acrylate polymers. This is related to the presence of a population of nuclear spins having short T₂ relaxation times that cannot be detected under high-resolution NMR and MRI conditions. This study involved multiple reactions and reactants, such as 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3HPLC of Formula: 3063-94-3).

1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.HPLC of Formula: 3063-94-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Larvicidal activity of Brunfelsia uniflora extracts on Aedes aegypti larvae was written by Sugauara, Elaine Yae Yamashita;Sugauara, ElisangelaYumi;Sugauara, Rosangela Rumi;Bortolucci, Wanessa de Campos;Fernandez, Carla Maria Mariano;Goncalves, Jose Eduardo;Colauto, Nelson Barros;Gazim, Zilda Cristiani;Linde, Giani Andrea. And the article was included in Natural Product Research in 2022.Related Products of 763-69-9 The following contents are mentioned in the article:

The aim of this study was to evaluate the chem. composition and the larvicidal activity of Brunfelsia uniflora leaf and flower extracts against Aedes aegypti larvae. Twenty-four compounds were found in the leaf extract, and the major compounds were phytol (23.1%), 9,12,15-octadecatrienoic acid, Et ester (21.3%), and hexadecanoic acid, Et ester (12.8%). In the flower extract, twenty-four compounds were also identified and the major compounds were α-amyrin (35.7%), β-amyrin (16.4%), and (EE)-geranyl linalool (9.6%) by gas chromatog. coupled to mass spectrometry. The larvicidal activity was evaluated by larval immersion test. The lethal concentrations (LC) obtained from leaf extract were LC₅₀ = 4.89 and LC_99.9 = 11.14 mg/mL and from flower extract were LC₅₀ = 3.82 and LC_99.9 = 11.03 mg/mL, and the pos. control presented LC₅₀ = 0.40 and LC_99.9 = 1.14 mg/mL. Thus, B. uniflora extracts are promising alternatives to control A. aegypti larvae. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Related Products of 763-69-9).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Related Products of 763-69-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A novel QSPR model for prediction of lower flammability limits of organic compounds based on support vector machine was written by Pan, Yong;Jiang, Juncheng;Wang, Rui;Cao, Hongyin;Cui, Yi. And the article was included in Journal of Hazardous Materials in 2009.Synthetic Route of C7H14O3 The following contents are mentioned in the article:

A quant. structure-property relationship (QSPR) study is suggested for the prediction of lower flammability limits (LFLs) of organic compounds Various kinds of mol. descriptors were calculated to represent the mol. structures of compounds, such as topol., charge, and geometric descriptors. Genetic algorithm was employed to select optimal subset of descriptors that have significant contribution to the overall LFL property. The novel chemometrics method of support vector machine was employed to model the possible quant. relationship between these selected descriptors and LFL. The resulted model showed high prediction ability that the obtained root mean square error and average absolute error for the whole dataset were 0.069 and 0.051 volume%, resp. The results were also compared with those of previously published models. The comparison results indicate the superiority of the presented model and reveal that it can be effectively used to predict the LFL of organic compounds from the mol. structures alone. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Synthetic Route of C7H14O3).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Synthetic Route of C7H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Molecular structural discrimination of chemical compounds in body odor using their GC-MS chromatogram and clustering methods was written by Jha, Sunil Kr.;Hayashi, Kenshi. And the article was included in International Journal of Mass Spectrometry in 2017.Recommanded Product: 2-Ethylhexyl benzoate The following contents are mentioned in the article:

In the present study, body odor samples have been collected according to different sampling protocols and characterized using the gas chromatog. (GC)-mass spectrometry (MS) technique with the objective to investigate the existence of different volatile organic compounds (VOCs) belonging to several chem. classes in body odor composition Moreover, the characterization outcomes have been validated by analyzing spectral information using substantial clustering methods. Specifically, the data matrix based on peak height of chem. compounds in each experiment has been analyzed by using six clustering methods, including principal component anal. (PCA), k-means clustering, fuzzy c-means clustering, hierarchical cluster anal., fuzzy clustering, and k-medoids clustering. Chem. compounds were well clustered into several groups with each of the implemented clustering methods which endorse the exptl. characterization outcomes and establishes the existence of VOCs from multiple chem. classes in body odor composition This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7Recommanded Product: 2-Ethylhexyl benzoate).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Recommanded Product: 2-Ethylhexyl benzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Degree of crosslinking in β-cyclodextrin-based nanosponges and their effect on piperine encapsulation was written by Guineo-Alvarado, Juan;Quilaqueo, Marcela;Hermosilla, Jeyson;Gonzalez, Sofia;Medina, Camila;Rolleri, Aldo;Lim, Loong-Tak;Rubilar, Monica. And the article was included in Food Chemistry in 2021.COA of Formula: C13H10O3 The following contents are mentioned in the article:

Piperine (PIP) is an alkaloid which is potent as a therapeutic agent. However, its applications are restricted by its poor water solubility Nanosponges (NS) derived from polymers are versatile carriers for poor water-soluble substances. The aim of this work was to synthesize β-cyclodextrin NS, by microwave-assisted fusion, for the encapsulation of PIP. Different formulations of NS were synthesized by varying the molar ratio of β-cyclodextrin:diphenyl carbonate (β-CD:DPC; 1:2, 1:6 and 1:10). NS specimens derived from 1:2, 1:6 and 1:10 β-CD:DPC molar ratios exhibited degree of substitution values of 0.345, 0.629 and 0.878, resp. The crystallinity of NS was enhanced by increasing di-Ph carbonate concentration A high degree of crosslinking in the NS increased the loading efficiency due to increased surface area available for bioactive inclusion. This study demonstrated the feasibility of synthesizing NS derived from β-cyclodextrin of high crystallinity for the encapsulation of PIP at high loading capacity. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0COA of Formula: C13H10O3).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.COA of Formula: C13H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Comparative Lipidomics Analysis of Human Milk and Infant Formulas Using UHPLC-Q-TOF-MS was written by Zhang, Xiuxiu;Liu, Lu;Wang, Lina;Pan, Yue;Hao, Xinyue;Zhang, Gengxu;Li, Xiaodong;Hussain, Muhammad. And the article was included in Journal of Agricultural and Food Chemistry in 2021.Recommanded Product: (2R,9Z)-1-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)-3-(palmitoyloxy)propan-2-yl oleate The following contents are mentioned in the article:

The lipidome and fatty acid composition of human milk and different infant formulas with animal- and/or plant-based fat sources are analyzed and compared in this study. The results obtained using pos. and neg. ionization modes indicate that there are 48 and 71 lipid species, resp., that are common between the human milk and infant formulas. Moreover, the fatty acid composition in infant formulas varies significantly, depending on the fat source. Human milk is rich in triacylglycerols that contain linoleic acid, α-linolenic acid, arachidonic acid, and docosahexaenoic acid. Meanwhile, the triacylglycerols in IFB comprise long-chain fatty acids at the sn-1,3 position. Compared to human milk, IFC has the same level of sphingomyelin species. Based on univariate and multivariate analyses, there are 37, 34, 31, and 36 lipid species that can be used to distinguish between human milk and infant formulas. Overall, the results reported herein are useful in designing new milk formulas that better mimic human milk. This study involved multiple reactions and reactants, such as (2R,9Z)-1-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)-3-(palmitoyloxy)propan-2-yl oleate (cas: 26662-94-2Recommanded Product: (2R,9Z)-1-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)-3-(palmitoyloxy)propan-2-yl oleate).

(2R,9Z)-1-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)-3-(palmitoyloxy)propan-2-yl oleate (cas: 26662-94-2) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Recommanded Product: (2R,9Z)-1-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)-3-(palmitoyloxy)propan-2-yl oleate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Depolymerization of End-of-Life Poly(bisphenol A carbonate) via 4-Dimethylaminopyridine-Catalyzed Methanolysis was written by Alberti, Christoph;Enthaler, Stephan. And the article was included in Waste and Biomass Valorization in 2020.Application In Synthesis of Diphenyl carbonate The following contents are mentioned in the article:

The chem. recycling, a sequence of depolymerization and polymerization reactions, of end-of-life plastics/polymers can contribute to a sustainable, resource-conserving and environmental-benign society. In this regard, we have set up a protocol for the depolymerization of end-of-life poly(bisphenol A carbonate). In more detail, applying a combination of methanol and catalytic amounts of 4-dimethylaminopyridine (DMAP) end-of-life poly(bisphenol A carbonate) was depolymerized to bisphenol A and di-Me carbonate. With the aid of microwave heating an excellent rate of depolymerization ( > 99%) within short reaction times (5 min) and turnover frequencies up to 1164 h^-1 were achieved. Moreover, it was demonstrated that phenolysis can be applied under optimized reaction conditions resulting in the formation of the mixture bisphenol A and di-Ph carbonate, which can be used for the synthesis of new poly(bisphenol A carbonate). In consequence a closed cycle for poly(bisphenol A carbonate) is feasible. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Application In Synthesis of Diphenyl carbonate).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application In Synthesis of Diphenyl carbonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Extraction of extracellular lipids from chemoautotrophic bacteria Serratia sp. ISTD04 for production of biodiesel was written by Bharti, Randhir K.;Srivastava, Shaili;Thakur, Indu Shekhar. And the article was included in Bioresource Technology in 2014.Application of 1731-94-8 The following contents are mentioned in the article:

A CO₂ sequestering bacterial strain, Serratia sp. ISTD04, that produces a significant amount of extracellular lipids was isolated from marble mine rocks. ¹⁴C labeling anal. revealed that the rate of assimilation of CO₂ by the strain is 0.756 × 10^-9 μmol CO₂ fixed cell^-1 h^-1. It was found to produce 466 mg/l of extracellular lipid which was characterized using ¹H NMR. After transesterification of lipids, the total saturated and unsaturated FAME was found to be 51% and 49% resp. The major FAME contained in the biodiesel were palmitic acid Me ester (C16:0), oleic acid Me ester (C18:1) and 10-nonadecenoic acid Me ester (C19:1). Biodiesel produced by Serratia sp. ISTD04 is balanced in terms of FAME composition of good quality. It also contained higher proportion of oleic acid (35%) which makes it suitable for utilization in existing engines. Thus, the strain can be harnessed com. to sequester CO₂ into biodiesel. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Application of 1731-94-8).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application of 1731-94-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tideglusib and Its Analogues As Inhibitors of Staphylococcus aureus SrtA was written by Yang, Teng;Zhang, Tao;Guan, Xiang-Na;Dong, Ze;Lan, Lefu;Yang, Song;Yang, Cai-Guang. And the article was included in Journal of Medicinal Chemistry in 2020.Product Details of 2253-73-8 The following contents are mentioned in the article:

Sortase A (SrtA) anchors surface proteins to the cell wall envelope, and it has attracted increasing interesting as a potential antivirulence target. Several small-mol. inhibitors for SrtA have been developed, but target validation remains largely underexplored. Herein, we report a new class of SrtA inhibitors that supports antivirulence therapy through small-mol. targeting of SrtA. Tideglusib (TD), a drug candidate for myotonic dystrophy, was outstanding in high-throughput screening. A concise synthetic route quickly provided TD analogs, and the structure-activity relationships for SrtA inhibition have been established from those analogs. Several compounds largely retained the in vitro potency and exhibited a better solubility than TD. Addnl., TD attenuated virulence-related phenotypes in vitro and protected mice against lethal S. aureus USA300 bacteremia. Our study indicates that TD and its analogs could be new candidates as SrtA inhibitors with potential in the development of new antivirulence agents. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Product Details of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Product Details of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tideglusib and Its Analogues As Inhibitors of Staphylococcus aureus SrtA was written by Yang, Teng;Zhang, Tao;Guan, Xiang-Na;Dong, Ze;Lan, Lefu;Yang, Song;Yang, Cai-Guang. And the article was included in Journal of Medicinal Chemistry in 2020.SDS of cas: 2253-73-8 The following contents are mentioned in the article:

Sortase A (SrtA) anchors surface proteins to the cell wall envelope, and it has attracted increasing interesting as a potential antivirulence target. Several small-mol. inhibitors for SrtA have been developed, but target validation remains largely underexplored. Herein, we report a new class of SrtA inhibitors that supports antivirulence therapy through small-mol. targeting of SrtA. Tideglusib (TD), a drug candidate for myotonic dystrophy, was outstanding in high-throughput screening. A concise synthetic route quickly provided TD analogs, and the structure-activity relationships for SrtA inhibition have been established from those analogs. Several compounds largely retained the in vitro potency and exhibited a better solubility than TD. Addnl., TD attenuated virulence-related phenotypes in vitro and protected mice against lethal S. aureus USA300 bacteremia. Our study indicates that TD and its analogs could be new candidates as SrtA inhibitors with potential in the development of new antivirulence agents. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8SDS of cas: 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.SDS of cas: 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics