Month: December 2022

Sex pheromones of two noctuid moths was written by Nesbitt, Brenda F.;Beevor, P. S.;Cole, R. A.;Lester, R.;Poppi, R. G.. And the article was included in Nature (London), New Biology in 1973.Synthetic Route of C14H24O2 The following contents are mentioned in the article:

The attractant scent in Diparopsis castanea consisted of 1-dodecyl acetate (I), trans-9-decen-1-yl acetate (II), 11-dodecen-1-yl acetate (III), and trans-9,11-dodecadien-1-yl acetate (IV). Electroantennogram responses of the male moths were in the order: IV ≫ II > III ≫ I. In laboratory trap tests, only IV was slightly attractive at low loadings. The addition of 20-30% III greatly enhanced the attractiveness of IV. The female Spodoptera littoralis sex scent consisted of 1-tetradecyl acetate (V), cis-9-tetradecen-1-yl acetate (VI), trans-11-tetradecen-1-yl acetate (VII), and cis-9,trans-11-tetradecadien-1-yl acetate (VIII). Electroantennogram responses of the male moths were in the order: VIII > VI ≫ VII > V. In laboratory trap testing, the natural proportions of V, VI, VII, and VIII were attractive. Brushes of the male S. littoralis located near the abdominal tip contained VIII. S. littoralis females gave electroantennogram responses to V, VI, VII, and VIII. This study involved multiple reactions and reactants, such as (E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7Synthetic Route of C14H24O2).

(E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Synthetic Route of C14H24O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Accelerating Biphasic Biocatalysis through New Process Windows was written by Huynh, Florence;Tailby, Matthew;Finniear, Aled;Stephens, Kevin;Allemann, Rudolf K.;Wirth, Thomas. And the article was included in Angewandte Chemie, International Edition in 2020.Product Details of 112-14-1 The following contents are mentioned in the article:

Process intensification through continuous flow reactions has increased the production rates of fine chems. and pharmaceuticals. Catalytic reactions are accelerated through an unconventional and unprecedented use of a high-performance liquid/liquid counter current chromatog. system. Product generation is significantly faster than in traditional batch reactors or in segmented flow systems, which is exemplified through stereoselective phase-transfer catalyzed reactions. This methodol. also enables the intensification of biocatalysis as demonstrated in high yield esterifications and in the sesquiterpene cyclase-catalyzed synthesis of sesquiterpenes from farnesyl diphosphate as high-value natural products with applications in medicine, agriculture and the fragrance industry. Product release in sesquiterpene synthases is rate limiting due to the hydrophobic nature of sesquiterpenes, but a biphasic system exposed to centrifugal forces allows for highly efficient reactions. This study involved multiple reactions and reactants, such as Octyl acetate (cas: 112-14-1Product Details of 112-14-1).

Octyl acetate (cas: 112-14-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Product Details of 112-14-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Atomic structures of closed and open influenza B M2 proton channel reveal the conduction mechanism was written by Mandala, Venkata S.;Loftis, Alexander R.;Shcherbakov, Alexander A.;Pentelute, Bradley L.;Hong, Mei. And the article was included in Nature Structural & Molecular Biology in 2020.Synthetic Route of C39H76NO8P The following contents are mentioned in the article:

Abstract: The influenza B M2 (BM2) proton channel is activated by acidic pH to mediate virus uncoating. Unlike influenza A M2 (AM2), which conducts protons with strong inward rectification, BM2 conducts protons both inward and outward. Here we report 1.4- and 1.5-Å solid-state NMR structures of the transmembrane domain of the closed and open BM2 channels in a phospholipid environment. Upon activation, the transmembrane helixes increase the tilt angle by 6° and the average pore diameter enlarges by 2.1 Å. BM2 thus undergoes a scissor motion for activation, which differs from the alternating-access motion of AM2. These results indicate that asym. proton conduction requires a backbone hinge motion, whereas bidirectional conduction is achieved by a sym. scissor motion. The proton-selective histidine and gating tryptophan in the open BM2 reorient on the microsecond timescale, similar to AM2, indicating that side chain dynamics are the essential driver of proton shuttling. This study involved multiple reactions and reactants, such as (2R,9Z)-1-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)-3-(palmitoyloxy)propan-2-yl oleate (cas: 26662-94-2Synthetic Route of C39H76NO8P).

(2R,9Z)-1-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)-3-(palmitoyloxy)propan-2-yl oleate (cas: 26662-94-2) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Synthetic Route of C39H76NO8P

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Physicochemical properties and oxidative stability of duck fat-added margarine for reducing the use of fully hydrogenated soybean oil was written by Shin, Dong-Min;Yune, Jong Hyeok;Kim, Tae-Kyung;Kim, Yea Ji;Kwon, Hyuk Cheol;Kim, Do Hyun;Jeong, Chang Hee;Choi, Yun-Sang;Han, Sung Gu. And the article was included in Food Chemistry in 2021.Recommanded Product: Glyceryl monostearate The following contents are mentioned in the article:

Soybean oil (SBO) and fully hydrogenated soybean oil (FHSBO) have been used for margarine production However, SBO-based margarine requires a considerable amount of trans fatty acid-containing FHSBO due to its low m.p. We aimed to reduce the FHSBO content in margarine by employing duck fat, which has a higher m.p. than SBO. Margarines were prepared using different ratios of duck fat and reduced levels of SBO and FHSBO. Physicochem., sensory, and oxidative properties of the margarines were evaluated. The quality characteristics of margarine improved when duck fat replaced SBO and FHSBO. Furthermore, the lipid oxidation parameters were lower in duck fat-added margarines than the control during storage at 60°C for 28 days. The margarine containing 80% duck fat showed the best sensory properties. Collectively, duck fat can replace SBO in margarine while reducing the use of FHSBO and maintaining desirable physicochem. properties, oxidative stability, and sensory properties. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Recommanded Product: Glyceryl monostearate).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: Glyceryl monostearate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Click Pt(IV)-carbohydrates pro-drugs for treatment of osteosarcoma was written by Moynihan, Eoin;Bassi, Giada;Ruffini, Andrea;Panseri, Silvia;Montesi, Monica;Velasco-Torrijos, Trinidad;Montagner, Diego. And the article was included in Frontiers in Chemistry (Lausanne, Switzerland) in 2021.Synthetic Route of C16H22O11 The following contents are mentioned in the article:

The selectivity vs. cancer cells has always been a major challenge for chemotherapeutic agents and in particular for cisplatin, one of the most important anticancer drugs for the treatment of several types of tumors. One strategy to overtake this challenge is to modify the coordination sphere of the metallic center with specific vectors whose receptors are overexpressed in the tumoral cell membrane, such as monosaccharides. In this paper, we report the synthesis of four novel glyco-modified Pt(IV) pro-drugs, based on cisplatin scaffold, and their biol. activity against osteosarcoma (OS), a malignant tumor affecting in particular adolescents and young adults. The sugar moiety and the Pt scaffold are linked exploiting the Copper Azide Alkyne Cycloaddition (CUAAC) reaction, which has become the flagship of click chem. due to its versatility and mild conditions. Cytotoxicity and drug uptake on three different OS cell lines as well as CSCs (Cancer Stem Cell) are described. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Synthetic Route of C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Synthetic Route of C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Qualitative and semi-quantitative analysis of specific aroma in Ampelopsis grossedentata based on HS-SPME/GC-MS was written by Shen, Dong;Shen, Qiang;Pan, Ke;Zheng, Wen-jia. And the article was included in Guizhou Nongye Kexue in 2010.Synthetic Route of C15H22O2 The following contents are mentioned in the article:

The specific aroma components of Ampelopsis grossedentata were qual. and semi-quant. analyzed by HS-SPME/GC-MS based on optimization of sample dosage, extraction temperature, extraction time, balanced time and desorption time to provide theor. basis for further development of Ampelopsis grossedentata. The results showed that the optimum HS-SPME conditions were 0.5 g sample dosage, 50°C, 50 min extraction time, 10 min balanced time, 2.5 min absorption time. The specific aroma components were nonanal, decanal, cis-geranylacetone, 6,10,14-trimethyl-2-pentadecanone, di-Et phthalate, phthalic acid, diisobutyl ester, 2,6-bis(1,1-dimethylethyl)-4-methyl-phenol, 2,4-bis(1,1-dimethylethyl)-phenol, β-ionone, 1,1,3-trimethyl-3-phenyl-indane and (R)-5,6,7,7a-tetrahydro-4,4,7a-trimethyl-2(4H)-benzofuranone. The HS-SPME/GC-MS with less sample dosage, reliability, simplicity and rapidity can be used in qual. and semi-quant. anal. of Ampelopsis grossedentata specific aroma components. This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7Synthetic Route of C15H22O2).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Synthetic Route of C15H22O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Surfactant based nanoreactor micellar assembly: An innovative route for synthesis of 2-thioxo-2,3-dihydroquinazolin-4(1H)-ones was written by Patil, Mayuri V.;Mhaldar, Pradeep M.;Tayade, Shivaji N.;Rashinkar, Gajanan S.;Pore, Dattaprasad M.. And the article was included in Journal of Molecular Liquids in 2022.Synthetic Route of C4H7NS The following contents are mentioned in the article:

An innovative route for synthesis of 2-thioxo-2,3-dihydroquinazolin-4(1H)-ones using isatoic anhydride and Ph isothiocyanate via in-situ formation of anthranilic acid was described. The reaction was performed in the nano-micellar assembly of surfactant, 4-(dimethylamino)-1-hexadecylpyridinium hydroxide [DAHP]⁺[OH]^– as a nano-reactor. The micelle concentration of surfactant is found to be 0.002 mol.dm^-3 using the conductivity data. The micellar particle dimensions were demonstrated from small-angle X-ray scattering (SAXS) anal. viz. micelle diameter and the interspacing between two micelles which were found to be 14.8 nm and 2.6 nm, resp. From the TGA anal., the surfactant is thermally stable up to 250°C with 76.01% weight loss. The practical simplicity, atom economy, good to high yields, ease of product isolation and purification, water as eco-benign solvent and catalyst recyclability were the remarkable aspects of the present methodol. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Synthetic Route of C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Synthetic Route of C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Surfactant based nanoreactor micellar assembly: An innovative route for synthesis of 2-thioxo-2,3-dihydroquinazolin-4(1H)-ones was written by Patil, Mayuri V.;Mhaldar, Pradeep M.;Tayade, Shivaji N.;Rashinkar, Gajanan S.;Pore, Dattaprasad M.. And the article was included in Journal of Molecular Liquids in 2022.Product Details of 2253-73-8 The following contents are mentioned in the article:

An innovative route for synthesis of 2-thioxo-2,3-dihydroquinazolin-4(1H)-ones using isatoic anhydride and Ph isothiocyanate via in-situ formation of anthranilic acid was described. The reaction was performed in the nano-micellar assembly of surfactant, 4-(dimethylamino)-1-hexadecylpyridinium hydroxide [DAHP]⁺[OH]^– as a nano-reactor. The micelle concentration of surfactant is found to be 0.002 mol.dm^-3 using the conductivity data. The micellar particle dimensions were demonstrated from small-angle X-ray scattering (SAXS) anal. viz. micelle diameter and the interspacing between two micelles which were found to be 14.8 nm and 2.6 nm, resp. From the TGA anal., the surfactant is thermally stable up to 250°C with 76.01% weight loss. The practical simplicity, atom economy, good to high yields, ease of product isolation and purification, water as eco-benign solvent and catalyst recyclability were the remarkable aspects of the present methodol. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Product Details of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Product Details of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Natural or Synthetic RNA Delivery: A Stoichiometric Comparison of Extracellular Vesicles and Synthetic Nanoparticles was written by Murphy, Daniel E.;de Jong, Olivier G.;Evers, Martijn J. W.;Nurazizah, Maratussholikhah;Schiffelers, Raymond M.;Vader, Pieter. And the article was included in Nano Letters in 2021.Reference of 1224606-06-7 The following contents are mentioned in the article:

RNA therapeutics have high potential that is yet to be fully realized, largely due to challenges involved in the appropriate delivery to target cells. Extracellular vesicles (EVs) are lipid bound nanoparticles released by cells of all types and possess numerous features that may help overcome this hurdle and have emerged as a promising RNA delivery vehicle candidate. Despite extensive research into the engineering of EVs for RNA delivery, it remains unclear how the intrinsic RNA delivery efficiency of EVs compares to currently used synthetic RNA delivery vehicles. Using a novel CRISPR/Cas9-based RNA transfer reporter system, we compared the delivery efficiency of EVs to clin. approved state-of-the-art DLin-MC3-DMA lipid nanoparticles and several in vitro transfection reagents. We found that EVs delivered RNA several orders of magnitude more efficiently than these synthetic systems. This finding supports the continued research into EVs as potential RNA delivery vehicles. This study involved multiple reactions and reactants, such as (6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate (cas: 1224606-06-7Reference of 1224606-06-7).

(6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate (cas: 1224606-06-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Reference of 1224606-06-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Determination of double-bond position in diunsaturated compounds by mass spectrometry of dimethyl disulfide derivatives was written by Vincent, Marco;Guglielmetti, Gianfranco;Cassani, Giorgio;Tonini, Cristina. And the article was included in Analytical Chemistry in 1987.Related Products of 50767-78-7 The following contents are mentioned in the article:

A method for determining the double-bond location in 24 diunsatd. compounds was examined The diene system is reacted with Me₂S₂ and a stoichiometric amount of iodine in CS₂ (or without solvent). The derivatization leads to either linear or cyclic polythioethers, depending on the number of CH₂ groups separating the 2 double bonds. The mass spectra of the derivatization products show fragmentation which is strongly influenced by the sulfurated groups introduced, so that the original position of the double bonds is easily deduced. Only conjugated dienes give derivatives with scarcely meaningful mass spectra. The derivatization has a moderate anti stereoselectivity when cyclic polythioethers are obtained, since several diastereomers can be distinguished by gas chromatog. No conclusive statement is possible about the stereochem. of the derivatization leading to linear polythioethers, where a different reaction mechanism is observed This study involved multiple reactions and reactants, such as (E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7Related Products of 50767-78-7).

(E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Related Products of 50767-78-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics