Month: December 2022

4-Methyltetrahydropyran (4-MeTHP): Application as an Organic Reaction Solvent was written by Kobayashi, Shoji;Tamura, Tomoki;Yoshimoto, Saki;Kawakami, Takashi;Masuyama, Araki. And the article was included in Chemistry – An Asian Journal in 2019.Quality Control of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate The following contents are mentioned in the article:

For the first time, a comprehensive study on the performance of 4-methyltetrahydropyran (4-MeTHP) as an organic reaction solvent was reported. Its broad application to organic reactions includes radical, Grignard, Wittig, organometallic, halogen-metal exchange, reduction, oxidation, epoxidation, amidation, esterification, metathesis, and other miscellaneous organic reactions. This application suggests that 4-MeTHP can serve as a substitute for conventional ethers and harmful halogenated solvents. However, 4-MeTHP was found incompatible with strong Lewis acids, and the C-O bond was readily cleaved by treatment with BBr₃. Moreover, the radical-based degradation pathways of 4-MeTHP, THP and 2-MeTHF were elucidated on the basis of GC-MS analyses. The data reported herein is anticipated to be useful for a broad range of synthetic chemists, especially industrial process chemists, when selecting the reaction solvent with green chem. perspectives. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Quality Control of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Quality Control of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Simple and reliable prediction of toxicological activities of benzoic acid derivatives without using any experimental data or computer codes was written by Keshavarz, Mohammad Hossein;Pouretedal, Hamid Reza. And the article was included in Medicinal Chemistry Research in 2013.Recommanded Product: 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

Most of the benzoic acid derivatives can exhibit toxicity through serious public health and environmental problems. A reliable correlation is introduced for desk calculation of benzoic acid derivatives in rats via oral 50 % LD (LD₅₀). It can be easily used for any benzoic acid compound containing the carbon, hydrogen, nitrogen, oxygen and halogen atoms, or their sodium salts. The novel correlation is based on nitrogens, oxygens, and halogens as well as two correcting functions for increasing and decreasing toxicity of benzoic derivatives, which arise from some specific structural moieties. The predicted results for the toxicity of 81 benzoic acid derivatives in rats via oral LD₅₀ are more reliable than reported values by training and test sets of quant. structure-toxicity relationship (QSTR). The forecasting ability of the new model has also been checked for further 134 benzoic acid derivatives containing complex mol. structures. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Recommanded Product: 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Recommanded Product: 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pharmacological studies of 1-(p-chlorophenyl)propanol and 2-(1-hydroxy-3-butenyl)phenol: two new non-narcotic analgesics designed by molecular connectivity was written by Garcia-March, F. J.;Garcia-Domenech, R.;Galvez, J.;Anton-Fos, G. M.;de Julian-Ortiz, J. V.;Giner-Pons, R.;Recio-Iglesias, M. C.. And the article was included in Journal of Pharmacy and Pharmacology in 1997.Application of 5003-48-5 The following contents are mentioned in the article:

Mol. topol. has been applied to the design of new analgesic drugs. Linear discriminant anal. and connectivity functions were used to design two potentially suitable drugs which were synthesized and tested for analgesic properties by the acetic acid-induced abdominal constriction test in mice and the tail-flick test in rats. In mice, the compound 1-(p-chlorophenyl)propanol showed higher analgesic activity, both i.p. and orally, then acetylsalicylic acid. 2-(1-Hydroxy-3-butenyl)phenol exhibited a lesser protective effect (70% of that shown by acetylsalicylic acid). In rats, acetylsalicylic acid gave the greatest protection against pain when administered i.p., while 1-(p-chlorophenyl)propanol was the most active orally. The 2-(1-hydroxy-3-butenyl)phenol, both i.p. and orally, showed the least protective effect. These results demonstrated the peripheral analgesic properties of the selected compounds, thus confirming the validity of the mol. design method. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Application of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Isolation and identification of Lactobacillus and yeast species and their effect on the quality of fermented rice cakes was written by He, Li;Chen, Yanhua;Zhang, Haitian;Wang, Hui;Chen, Shujuan;Liu, Shuliang;Liu, Aiping;Li, Qin;Ao, Xiaolin;Liu, Yaowen. And the article was included in Innovative Food Science & Emerging Technologies in 2022.SDS of cas: 1731-94-8 The following contents are mentioned in the article:

In this study, microbes were isolated from the rice slurry of a fermented rice cake to obtain lactic acid bacteria and yeast species. These species were identified using microbial physiol. and gene sequence analyses. As the growth of the lactic acid bacterial strain R-2b and the yeast J-3a strains were found to be the best, a composite starter comprising these microbes was used for the preparation of fermented rice cakes. Based on single factor and orthogonal experiments, when the proportion of Lactobacillus plantarum, Saccharomyces cerevisiae, and Candida humilis was 1:3:6, the optimal fermentation conditions were addition of sugar and starter amounts of 20% and 6%, resp., a fermentation temperature of 32°C, and fermentation time of 8 h. The fermented rice cake with this optimum ratio had the most abundant volatile components and qualified physicochem. and microbial indexes. Addnl., the overall quality was better than that of com. available products. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8SDS of cas: 1731-94-8).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.SDS of cas: 1731-94-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effects of Glyceryl Monostearate on the Retrogradation of Pea Starch was written by Wang, Ling;Lan, Xuyue;Xu, Wen;Du, Qinling;Deng, Sha;Jia, Dongying. And the article was included in Starch/Staerke in 2022.Recommanded Product: Glyceryl monostearate The following contents are mentioned in the article:

Pea starch (PS) jelly is prone to retrograde, resulting in increased hardness and decreased taste. Based on this, the effects of glyceryl monostearate (GMS) on the retrogradation properties of pea starch are investigated. The rheol., texture, thermal, mol., and crystal properties of PS-GMS blends are studied, and the possible interaction between PS and GMS is also analyzed. The addition of GMS reduces the hardness of pea starch gel, increases its springiness, and improves its quality. As the concentration of GMS increases, the onset temperature, conclusion temperature, and gelatinization enthalpy of the blend gels decrease. Moreover, GMS also reduces their ordered structure and crystallinity. The changes in the storage modulus after the addition of NaCl and urea indicate that GMS interactes with amylose mainly through hydrogen bonding. It can be concluded that GMS inhibits the retrogradation of PS gel by interacting with amylose through hydrogen bonds. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Recommanded Product: Glyceryl monostearate).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: Glyceryl monostearate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Regional features of northern Italian sparkling wines, identified using solid-phase micro extraction and comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry was written by Carlin, Silvia;Vrhovsek, Urska;Franceschi, Pietro;Lotti, Cesare;Bontempo, Luana;Camin, Federica;Toubiana, David;Zottele, Fabio;Toller, Giambattista;Fait, Aaron;Mattivi, Fulvio. And the article was included in Food Chemistry in 2016.Safety of Ethyl 3-ethoxypropanoate The following contents are mentioned in the article:

We carried out comprehensive mapping of volatile compounds in 70 wines, from 48 wineries and 6 vintages, representative of the two main production areas for Italian sparkling wines, by HS-SPME-GCxGC-TOF-MS and multivariate anal. The final scope was to describe the metabolomics space of these wines, and to verify whether the grape cultivar signature, the pedoclimatic influence of the production area, and the complex technol. were measurable in the final product. The wine chromatograms provided a wealth of information, with 1695 compounds being found. A large number of putative markers influenced by the cultivation area was observed A subset of 196 biomarkers fully discriminated between the two types of sparkling wines investigated. Among the new compounds, safranal and α-isophorone were observed We showed how correlation-based network anal. could be used as a tool to detect the differences in compound behavior based on external/environmental influences. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Safety of Ethyl 3-ethoxypropanoate).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Safety of Ethyl 3-ethoxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis and characterization of a small library of bis-glucosides: Influence of the nature of the diol/diphenol used in O-glucosylation was written by Patry, Stephane;Robitzer, Mike;Habas, Jean-Pierre. And the article was included in Carbohydrate Research in 2021.Electric Literature of C16H22O11 The following contents are mentioned in the article:

In this paper, the synthesis of different bisglucosides is investigated through the reaction of two acetylated glucose units with a diol (or diphenol) in order to develop a versatile mol. platform for the future development of bio-based polymers. A panel of five diols and one diphenol is initially used in order to examine the influence of their chem. skeleton on the reaction yield and both nature and proportion of formed species. Reaction products are identified using ¹H and ¹³C NMR spectroscopies completed by MALDI-TOF MS technique. The nucleophilicity of these dihydroxy compounds is identified as being the main factor that governs the reaction characteristics. In particular, the best selectivity is obtained with the use of hydroquinone. Inversely, byproducts (oligomers, deacetylated compounds) are observed with the diols defined by higher nucleophilicity despite the choice of stereoselective pathway using acyl protecting groups. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Electric Literature of C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Electric Literature of C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Application of a novel cavity nucleating agent based on cyclodextrin in polymer foaming materials and in situ visual injection moulding study was written by Zhou, Yuhui;He, Li;Gong, Wei. And the article was included in Journal of Materials Science in 2021.Formula: C13H10O3 The following contents are mentioned in the article:

In this study, β-cyclodextrin nanosponges were synthesized using organic carbonates, namely gelatinous β-cyclodextrin nanosponges (NJ) and vitreous β-cyclodextrin nanosponges (BL). The ‘constructed’ porous structures were characterized by SEM. NJ and BL with different cavity structures as heterogeneous nucleation agents were selected for the polypropylene and polylactic acid foaming injection molding processes. The obtained exptl. results showed that NJ significantly reduced nucleation energy barrier and thus exhibited the highest nucleation efficacy. The nucleation mechanism was explored via a combination of the classical nucleation theory and in situ visual injection molding anal. In a word, the current work provided an insight into the structure-nucleating efficiency relationship for porous particles and highlighted the importance of the construction of porous structures in the organic nucleating agents to improve the polymeric foaming performances. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Formula: C13H10O3).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Formula: C13H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Evaluation of flavor characteristics of bacon smoked with different woodchips by HS-SPME-GC-MS combined with an electronic tongue and electronic nose was written by Du, Hongzhen;Chen, Qian;Liu, Qian;Wang, Yan;Kong, Baohua. And the article was included in Meat Science in 2021.Quality Control of Methyl heptanoate The following contents are mentioned in the article:

This study investigated the effects of different woodchip types (beech, oak, pear, and apple) on the volatile compounds and sensory characteristics of smoked bacon. The volatile compounds were influenced by woodchip types and the total content of ketones and phenols in pear-smoked bacon were higher than in bacon smoked with other woodchips (P < 0.05). The E-tongue combined with E-nose can effectively distinguish the difference in the flavor of bacon smoked with different woodchip types by the signal intensities. Sensory anal. showed that smoking increased bacon′s redness, saltiness, and smoky flavor compared with the control (unsmoked bacon) (P < 0.05) and it had little impact on off-odor (P > 0.05). Correlation anal. showed that the E-nose and E-tongue data were highly correlated with contents of alcs., aldehydes, and ketones. This study revealed that the different smoked materials greatly influenced the flavor and sensory properties of bacon. This study involved multiple reactions and reactants, such as Methyl heptanoate (cas: 106-73-0Quality Control of Methyl heptanoate).

Methyl heptanoate (cas: 106-73-0) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Quality Control of Methyl heptanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Characterization of Odor-Active Compounds of Ichang Lemon (Citrus wilsonii Tan.) and Identification of Its Genetic Interspecific Origin by DNA Genotyping was written by Demarcq, Benoit;Cavailles, Margaux;Lambert, Laetitia;Schippa, Christine;Ollitrault, Patrick;Luro, Francois. And the article was included in Journal of Agricultural and Food Chemistry in 2021.Formula: C11H22O2 The following contents are mentioned in the article:

Ichang lemon is a citrus fruit whose rind gives off a delicious and much appreciated fragrance and flavor. The volatile components of the fruit peel of Ichang lemon were investigated by GC-MS and GC-O (AEDA method). Simultaneously, its genetic origin was identified by using diagnostic SNP markers specific to ancestral species and multiallelic SSR and InDel markers. Ichang lemon combines three ancestral genomes (Citrus maxima, Citrus ichangensis, and Citrus reticulata) and may be a pummelo x Yuzu hybrid. Although the major compounds of the Ichang lemon aromatic profile were present in Citrus junos, a few pummelo-specific compounds were also detected, such as indole and nootkatone, in agreement with its maternal lineage. 3-Methyl-3-sulfanylbutyl acetate, reported to occur in passion fruit and brewed coffee, was identified by GC-MS, GC-QTOF-MS, and GC-FTIR for the first time in citrus. This odor-active compound has a sulfurous, tropical fruity, green note. This study involved multiple reactions and reactants, such as Isopentyl hexanoate (cas: 2198-61-0Formula: C11H22O2).

Isopentyl hexanoate (cas: 2198-61-0) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Formula: C11H22O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics