Month: December 2022

Shi, Hongwei published the artcileCatalyst- and additive-free sunlight-induced autoxidation of aldehydes to carboxylic acids, Related Products of esters-buliding-blocks, the publication is Green Chemistry (2022), 24(15), 5835-5841, database is CAplus.

A catalyst- and additive-free sunlight-induced strategy for autoxidation of a wide range of aldehydes RCHO (R = Bu, cyclohexyl, Ph, pyridin-3-yl, etc.) to carboxylic acids RC(O)OH is described for the first time. In this oxidation system, air serves as the source of oxygen and sunlight as the light source, and the system includes the advantages of green, highly atom-efficient, and low-cost synthesis. This method was easily applied even at gram scale. The reaction proceeds smoothly even at lower temperature and in natural light.

Green Chemistry published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C8H16O2, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ma, Fei published the artcileDNA-Encoded Libraries: Hydrazide as a Pluripotent Precursor for On-DNA Synthesis of Various Azole Derivatives, COA of Formula: C9H8O4, the publication is Chemistry – A European Journal (2021), 27(31), 8214-8220, database is CAplus and MEDLINE.

A phylogenic chem. transformation strategy using DNA-conjugated benzoyl hydrazine as a common versatile precursor in azole chem. expansion of DNA-encoded combinatorial chem. library (DEL) has been described. DNA-compatible reactions deriving from the common benzoyl hydrazines, e.g., I (R = DNA) precursor showed excellent functional group tolerance with exceptional efficiency in the synthesis of various azoles, including oxadiazoles, e.g., II thiadiazoles, and triazoles, under mild reaction conditions. The phylogenic chem. transformation strategy provides DELs a facile way to expand into various unique chem. spaces with privileged scaffolds and pharmacophores.

Chemistry – A European Journal published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C9H8O4, COA of Formula: C9H8O4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zhao, Wei published the artcileEffects of guanidinoacetic acid and complex antioxidant supplementation on growth performance, meat quality, and antioxidant function of broiler chickens, Synthetic Route of 121-79-9, the publication is Journal of the Science of Food and Agriculture (2021), 101(9), 3961-3968, database is CAplus and MEDLINE.

This study was conducted to evaluate the effects of adding guanidinoacetic acid (GAA), or complex antioxidant (CA), or their combination, in diets on the growth performance, carcass traits, meat quality, and antioxidant capacity of broilers. A total of 192 25-day-old broilers were assigned to a 2 × 2 factorial design including two dietary supplements at two different levels, in which the main effects were the addition of GAA (0 or 600 mg kg^-1) and CA (0 or 150 mg kg^-1). This trial lasted for 18 days. Compared with the control group, the GAA group, CA group, and GAA + CA group, decreased feed conversion ratio by 7.02%, 6.58%, and 11.40%, resp. Guanidinoacetic supplementation increased eviscerated yield, pH_24h (P < 0.05). Complex antioxidant supplementation increased the a* values (P < 0.05). The combination of GAA and CA did not affect the carcass traits and meat quality. Guanidinoacetic acid alone and CA alone and combined with GAA and CA decreased the reactive oxygen species (ROS) level and malonaldehyde (MDA) content (P < 0.05), and the GAA + CA group had the lowest ROS level and MDA content of broilers. Dietary supplementation of GAA, CA or their combination had beneficial effects on growth performance and breast antioxidant capacity, and the combination of GAA and CA could exert a synergistic effect in improving antioxidant capacity.

Journal of the Science of Food and Agriculture published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C15H23BO2, Synthetic Route of 121-79-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Yu, Jin-Feng published the artcileCu-Mediated Amination of (Hetero)Aryl C-H bonds with NH Azaheterocycles, HPLC of Formula: 1877-71-0, the publication is Angewandte Chemie, International Edition (2019), 58(50), 18141-18145, database is CAplus and MEDLINE.

Direct synthesis of N-(hetero)arylated heteroarenes has been realized through Cu-mediated C-N coupling of NH azaheterocycles with aryl C-H bonds under aerobic conditions. This method features a broad scope of both heterocyclic arenes (pyridine, quinoline, pyrazole, imidazole, furan, thiophene, benzofuran, and indole) and NH azaheterocycles (imidazole, pyrazole, indole, azaindole, purine, indazole, benzimidazole, pyridone, carbazole), providing a versatile method for the synthesis of pharmaceutically important N-(hetero)arylated heteroarenes. The versatility of this reaction was further demonstrated through late-stage modification of marketed drugs and the synthesis of a key intermediate for accessing a class of angiotensin II receptor 1 antagonists.

Angewandte Chemie, International Edition published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C10H15NO, HPLC of Formula: 1877-71-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Xu, Dan published the artcileSelective oxidation of alcohols to high value-added carbonyl compounds using air over Co-Co₃O₄@NC catalysts, Related Products of esters-buliding-blocks, the publication is Chemical Engineering Journal (Amsterdam, Netherlands) (2022), 134545, database is CAplus.

The sustainable catalytic transformation of alcs. to high value-added fine chems. is a significant and challenging research topic. Herein, a set of nitrogen-doped carbon encapsulated Co-based catalysts (Co-Co₃O₄@NC-T) were prepared by using low-cost dicyandiamide, glyoxal and cobalt nitrate as precursors. The obtained catalysts were utilized for the selective oxidation of alcs. to high value-added esters and carboxylic acids with air as the oxygen source and displayed wide applicability for the oxidation of both aromatic and aliphatic alcs. Based on the controlled experiments, the protective effect of N-doped carbon structure and the synergistic effect between Co core and Co₃O₄ species guaranteed the high reaction conversion and selectivity. Benefitting from heterogeneity and magnetism of the catalyst, it can be easily recycled and reused for long-term stability. Reasonable mechanisms of selective oxidation reaction were proposed through EPR anal. and controlled experiments The present work provides a facile strategy for potential large-scale preparation of heterogeneous catalyst for sustainable and green catalytic transformations.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C5H10O2S, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sun, Maolin published the artcilePractical and rapid construction of 2-pyridyl ketone library in continuous flow, Application In Synthesis of 627-93-0, the publication is Journal of Flow Chemistry (2021), 11(2), 91-98, database is CAplus.

Herein, a practical method for the rapid synthesis of 2-pyridyl ketone ArC(O)R [Ar = 2-pyridyl; R = Me, Ph, Bn, etc.] library in continuous flow was reported, in which the 2-lithiopyridine formed by Br/Li exchange reacts with com. available esters to obtain 2-pyridyl ketones ArC(O)R in a good yield at short reaction time. This protocol functions broadly on a variety of esters and had been applied to the synthesis of TGF-β type 1 receptor inhibitor LY580276 intermediate ArC(O)R [Ar = 6-methyl-2-pyridyl; R = (4-fluorophenyl)methyl] in an environmentally friendly method. It was rapid, reliable, and cost-efficient to afford diverse kinds of 2-pyridyl ketones ArC(O)R in the compound library.

Journal of Flow Chemistry published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C17H37NO3, Application In Synthesis of 627-93-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zhao, Bowen published the artcileXanthate-Based Photoiniferter RAFT Polymerization toward Oxygen-Tolerant and Rapid Living 3D Printing, Related Products of esters-buliding-blocks, the publication is Macromolecules (Washington, DC, United States) (2022), 55(5), 1620-1628, database is CAplus.

Three-dimensional (3D) printing based on photoinduced reversible addition-fragmentation chain transfer (RAFT) polymerization is emerging as a versatile and powerful method to prepare “living” 3D objects, which can be postmodified with various functionalities. However, an addnl. photoinitiator or photocatalyst is necessary in these systems, which is toxic and will cause neg. effects on the properties of the prepared materials. Here, we report oxygen-tolerant and rapid living 3D printing based on photoiniferter RAFT polymerization, which does not need addnl. photoinitiators or photocatalysts. A xanthate, O-ethyl-S-2-Et propionate, was chosen as both the photoinitiator and RAFT agent in this process. Various monomers and RAFT agents were screened in this system. Materials with different properties were prepared utilizing the postfunctionalization of the printed living objects. Furthermore, a polymer welding method was proposed by painting fresh monomers between two living objects for post-photocuring. This photoiniferter RAFT polymerization-based living 3D printing method was also successfully applied to a com. digital light processing technique-based 3D printer, offering a facile method to fabricate living 3D materials with different shapes.

Macromolecules (Washington, DC, United States) published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C7H8BNO4, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Wang, Yixuan published the artcileWidely targeted metabolomics analysis of enriched secondary metabolites and determination of their corresponding antioxidant activities in Elaeagnus angustifolia var. orientalis (L.)Kuntze fruit juice enhanced by Bifidobacterium animalis subsp. Lactis HN-3 fermentation, Recommanded Product: Methyl 3-phenyl-2-propenoate, the publication is Food Chemistry (2022), 131568, database is CAplus and MEDLINE.

Elaeagnus angustifolia var. orientalis (L.)Kuntze fruit contains a large number of naturally occurring mols. present as glycoside, methylated, and Me ester conjugates, which should be hydolyzed or transformed to become bioactive forms. For this purpose, Bifidobacterium animalis subsp. lactis HN-3 was selected to ferment Elaeagnus angustifolia var. orientalis (L.)Kuntze fruit juice (EOJ). After fermentation, the total phenolic content (TPC) and antioxidant capacity of the EOJ increased significantly compared to the non-fermented EOJ. Using widely-targeted metabolomics anal., polyphenolic compounds involved in the flavonoid biosynthetic pathway were determined to be up-regulated in the fermented EOJ. In addition, the metabolites generated by 8 deglycosidation, 5 demethylation, 5 hydrogenation, and 28 other reactions were detected in higher concentrations in the fermented EOJ compared to the non-fermented EOJ. Interestingly, these up-regulated metabolites have higher antioxidant and other biol. activities than their metabolic precursors, which provide a theor. basis for the development of Bifidobacterium-fermented plant products with stronger functional activities.

Food Chemistry published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C9H21NO3, Recommanded Product: Methyl 3-phenyl-2-propenoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Gao, Yu published the artcileOrganic glass with superior optical properties based on dimethyl itaconate and diethyl itaconate, Quality Control of 617-52-7, the publication is Polymer Testing (2021), 107363, database is CAplus.

High light transmittance material was synthesized by di-Me itaconic acid and di-Et itaconic acid via piecewise bulk polymerization, using benzoyl peroxide (BPO) as catalyst. Its chem. structure was characterized by gel permeation chromatog. (GPC), NMR spectroscopy (NMR) and fourier transform IR spectroscopy (FTIR). The thermal performance of polymer was characterized by differential scanning calorimetry (DSC) and thermogravimetric anal. (TGA), showing its glass transition temperature (T_g) was between 52° and 72°, thermal decomposition temperature above 230°, suitable for processing. The transmittance of the polymer is as high as 92% and d. of 1.1 g/cm³, which has the optical device application potential. The authors also tested the hydrophilicity of the material surface by the contact angle test, combined with the data of simulated calculation to explore the influence factors of hydrophilic change on the material surface.

Polymer Testing published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C7H10O4, Quality Control of 617-52-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zhang, Xiaohua published the artcileSystematically Controlling Acceptor Fluorination Optimizes Hierarchical Morphology, Vertical Phase Separation, and Efficiency in Non-Fullerene Organic Solar Cells, Name: Dimethyl itaconate, the publication is Advanced Energy Materials (2022), 12(1), 2102172, database is CAplus.

Non-fullerene acceptor (NFA) end group (EG) functionalization, especially by fluorination, affects not only the energetics but also the morphol. of bulk-heterojunction (BHJ) organic solar cell (OSC) active layers, thereby influencing the power conversion efficiency (PCE) and other metrics of NFA-based OSCs. However, a quant. understanding of how varying the degrees of NFA fluorination influence the blend morphol. and photovoltaic properties remains elusive. Here a series of three A-DAD-A type NFAs (D = π-donor group and A = π-acceptor EG) which systematically increase the degree of EG fluorination and comprehensively investigate the resulting blends with the polymer donor PM6 in terms of optical properties, electronic structure, film crystallinity, charge carrier transport, and OSC performance is reported. The results indicate that the most highly fluorinated NFA, BT-BO-L4F, achieves an optimal BHJ hierarchical morphol. where enhanced NFA mol. intermol. π-π stacking and optimal vertical phase gradation are achieved in the BHJ blend. These factors also promote optimum NFA-cathode contact, more balanced electron and hole mobility, and suppress both monomol. and bimol. recombination. As a result, both the short-circuit c.d. and fill factor in this OSC series progressively increase with increasing EG fluorine d., and the resulting PCEs increase from 9 to 16.8%.

Advanced Energy Materials published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C7H8BFO2, Name: Dimethyl itaconate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics