Month: December 2022

Rodima, T. published the artcileSex attractants for some forest Lepidopterous species, Product Details of C14H26O2, the publication is Tartu Ulikooli Toimetised (1994), 193-201, database is CAplus.

Mixtures of Z- and E-8-dodecenylacetate, Z- and E-9-dodecenyl-acetate and resp. E-9 alc., E-10-dodecenylacetate, dodecylacetate as well as Z-9, E-11-tetradecadienylacetate were tested for their capacity of sex attracting forest pests such as Rhyacionia duplana, Blastesthia turionella, Dioryctria abietella, Cydia coniferana, C. strobilella, Semasia ratzeburgiana and Petrova resinella. Mass trapping of B. turionella and C. coniferana males to control the forest pest population was tested.

Tartu Ulikooli Toimetised published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Product Details of C14H26O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Hrdy, Ivan published the artcileNew records on sex attractants for males and faunistic comments on moths (Lepidoptera) from Czechoslovakia, SDS of cas: 16974-11-1, the publication is Acta Entomologica Bohemoslovaca (1989), 86(4), 252-68, database is CAplus.

(E)-5-Decen-1-ol, (E)-5-decen-1-yl acetate, (Z)-8-dodecen-1-ol, (Z)-8-dodecen-1-yl acetate, (E)-8-dodecen-1-yl acetate, (Z)-9-dodecen-1-yl acetate, (E)-9-dodecen-1-ol, (E)-9-dodecen-1-yl acetate, (E)-10-dodecen-1-yl acetate, (Z)-9-tetradecen-1-yl acetate, (Z)-11-tetradecen-1-yl acetate, (Z)-11-tetradecen-1-ol, (E,Z)-7,9-dodecadien-1-yl acetate, (E,E)-8,10-dodecadien-1-ol, (E,E)-8,10-dodecadien-1-yl acetate, dodecyl acetate, alone or as mixtures were screened for male moth attractancy at two localities in Central Bohemia. Species captured included representatives of the following families: Gracillariidae (3 species), Yponomeutidae (1), Oecophoridae (1), Elachistidae (1), Coleophoridae (1), Blastobasidae (1), Gelechiidae (4), Tortricidae (38), Pyralidae (1), Zygaenidae (2), Geometridae (1), Lymantriidae (2), Noctuidae (5). New sex attractants were found for some of the species recorded, e.g. Calybites aurogutella, Phyllonorycter mespilellus, Coleophora palliatella, Teleoides decorella, Oegoconia quadripuncta, Cydia gemmiferana, C. succedana, Eana derivana, Dichrorampha incursana, Spatalistis bifasciana, Zeiraphera isertana, Zygaena scabiosae. Chronic orchard pests such as Cydia pomonella, C. funebrana and Anarsia lineatella were abundant in pheromone traps located on uncultivated habitats. Catches of Apotomis infida, Cnephasia oxyacanthana, Cydia gemmiferana, Eana derivana and Pammene albugiana are remarkable, showing that pheromone traps can be used successfully as a complementary method in faunistics.

Acta Entomologica Bohemoslovaca published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, SDS of cas: 16974-11-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Peckh, Kamil published the artcileOxidation of 1,2-cyclohexanediol as a step for adipic acid synthesis, Category: esters-buliding-blocks, the publication is Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) (2022), 131-136, database is CAplus.

Adipic acid is the most important of the com. available aliphatic dicarboxylic acids. It is obtained industrially from cyclohexanone and/or cyclohexanol by oxidation with nitric acid(V). One of the byproducts of the process is nitrous oxide, which is difficult to utilize. In this paper we propose an alternative method of adipic acid synthesis. In the first stage, cyclohexene is oxidized with hydrogen peroxide to epoxide, which hydrolyzes to 1,2-cyclohexanediol that in the second stage is then oxidized with oxygen. From an environmental point of view, this two-stage method can offer a significant and attractive reduction of N₂O production compared to the industrial methods. We apply a simple catalytic system composed of transition metal compounds and HNO₃ or organic nitrites, to the second stage of adipic acid synthesis synthesis, namely 1,2-cyclohexenediol oxidation using oxygen.

Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C8H14O4, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ondono, Raul published the artcileDesign of novel small molecule base-pair recognizers of toxic CUG RNA transcripts characteristics of DM1, Application of Dimethyl itaconate, the publication is Computational and Structural Biotechnology Journal (2021), 51-61, database is CAplus and MEDLINE.

Myotonic Dystrophy type 1 (DM1) is an incurable neuromuscular disorder caused by toxic DMPK transcripts that carry CUG repeat expansions in the 3′ untranslated region (3′UTR). The intrinsic complexity and lack of crystallog. data makes noncoding RNA regions challenging targets to study in the field of drug discovery. In DM1, toxic transcripts tend to stall in the nuclei forming complex inclusion bodies called foci and sequester many essential alternative splicing factors such as Muscleblind-like 1 (MBNL1). Most DM1 phenotypic features stem from the reduced availability of free MBNL1 and therefore many therapeutic efforts are focused on recovering its normal activity. For that purpose, herein we present pyrido[2,3-d]pyrimidin-7-(8H)-ones, a privileged scaffold showing remarkable biol. activity against many targets involved in human disorders including cancer and viral diseases. Their combination with a flexible linker meets the requirements to stabilize DM1 toxic transcripts, and therefore, enabling the release of MBNL1. Therefore, a set of novel pyrido[2,3-d]pyrimidin-7-(8H)-ones derivatives (1a-e) were obtained using click chem. 1a exerted over 20% MBNL1 recovery on DM1 toxic RNA activity in primary cell biol. studies using patient-derived myoblasts. 1a promising anti DM1 activity may lead to subsequent generations of ligands, highlighting a new affordable treatment against DM1.

Computational and Structural Biotechnology Journal published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C7H10O4, Application of Dimethyl itaconate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Hu, Mingjun published the artcileA sustainable high-viscosity modified asphalt modified with multiple anti-aging agents: Micro-chemical analysis and macro-rheological characterization, Application of Tris(2,4-di-tert-butylphenyl) phosphite, the publication is Construction and Building Materials (2022), 127701, database is CAplus.

This study aimed to use aging inhibition technol. to actively improve the environmental aging resistance, thus achieving the sustainable and long-life application of high-viscosity modified asphalt (HVMA). The sustainable HVMAs with different anti-aging agents was prepared, and the long-term environmental aging effect, including solar radiation, heat, and moisture, was simulated using the accelerated environmental aging tester. Then, the chem. and mol. composition of sustainable HVMAs were investigated using Fourier transform IR spectroscopy test, XPS test, and gel permeation chromatog. test. Afterwards, the nano-indentation test was used to study the nanomech. property of sustainable HVMAs. Finally, the dynamic shear rheol. test and linear amplitude sweep test were applied to evaluate the aging resistance, crack resistance, and fatigue resistance of sustainable HVMAs. The results show that environmental aging leads to the rapid oxidation of asphalt mols. and substantial degradation of polymer mols. in HVMA, as evidenced by the transformation of carbon elements from C-C/C-H bonds to C-O/C=O bonds and sulfur elements from C-S-C bonds to S=O/O=S=O bonds. A single anti-aging agent has a little aging inhibition effect, while the compounding of multiple anti-aging agents has a synergistic anti-aging enhancement effect. The combination of UV absorbers and UV blocking agents can absorb/reflect some of the UV rays and delay the UV aging process. However, they cannot effectively prevent the binding of UV-excited reactive radicals with oxygen. In contrast, incorporating antioxidants can allow hydrogen atoms to combine with UV-excited reactive radicals and prevent further oxidation of asphalt mols. The compound incorporation of UV absorbers, UV blocking agents, and antioxidants can improve the rheol. property, crack resistance, and fatigue resistance of aged HVMA, thus effectively promoting the sustainable and long-life application of HVMA.

Construction and Building Materials published new progress about 31570-04-4. 31570-04-4 belongs to esters-buliding-blocks, auxiliary class Mono-phosphine Ligands, name is Tris(2,4-di-tert-butylphenyl) phosphite, and the molecular formula is C42H63O3P, Application of Tris(2,4-di-tert-butylphenyl) phosphite.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sun, Wenlong published the artcileRuthenium-Catalyzed Intramolecular Arene C(sp²)-H Amidation for Synthesis of 3,4-Dihydroquinolin-2(1H)-ones, COA of Formula: C10H10O2, the publication is Organic Letters (2021), 23(9), 3310-3314, database is CAplus and MEDLINE.

Authors report the [Ru(p-cymene)(L-proline)Cl]-catalyzed cyclization of 1,4,2-dioxazol-5-ones to form dihydroquinoline-2-ones in excellent yields with excellent regioselectivity via a formal intramol. arene C(sp²)-H amidation. The reactions of the 2- and 4-substituted aryl dioxazolones proceeds initially through spirolactamization via electrophilic amidation at the arene site, which is para or ortho to the substituent. A Hammett correlation study showed that the spirolactamization is likely to occur by electrophilic nitrenoid attack at the arene, which is characterized by a neg. ρ value of -0.73.

Organic Letters published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C20H28B2O4S2, COA of Formula: C10H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zhou, Junliang published the artcileAzetidine-Containing Heterospirocycles Enhance the Performance of Fluorophores, Quality Control of 1523571-10-9, the publication is Organic Letters (2020), 22(11), 4413-4417, database is CAplus and MEDLINE.

Fluorescent dyes are extensively utilized in various fluorescence imaging techniques. However, many existing modification strategies could not balance the performance (such as brightness, photostability, water solubility, and permeability) of fluorophores. Herein we report a general strategy to enhance the performance of donor-acceptor-type fluorophores by introducing azetidine-containing heterospirocycles to the commonly used fluorophore scaffolds. Such a strategy turned out to be a general way to develop high-quality fluorophores.

Organic Letters published new progress about 1523571-10-9. 1523571-10-9 belongs to esters-buliding-blocks, auxiliary class Azetidine,Salt,Spiro,Amide, name is tert-Butyl 1,6-diazaspiro[3.3]heptane-1-carboxylate oxalate(2:1), and the molecular formula is C13H18N2, Quality Control of 1523571-10-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Wang, Yingying published the artcileSelf-assembly and photo-responsive behavior of novel ABC₂-type block copolymers containing azobenzene moieties, Category: esters-buliding-blocks, the publication is Soft Matter (2012), 8(11), 3131-3138, database is CAplus.

The self-assembly behavior and photo-responsive properties of novel azobenzene based copolymers poly(ethylene oxide) monomethyl ether-block-polystyrene-block-{poly[6-(4-methoxy-azobenzene-4′-oxy)hexyl methacrylate]}₂ [MPEO-b-PS-b-(PMMAZO)₂] with various block lengths of PMMAZO segments in aqueous media were studied by means of transmission electron microscopy (TEM), SEM, laser light scattering (LLS) and UV-Vis spectrophotometry. It was found that the critical water content for the aggregate formation increases with the PMMAZO weight fraction. By tailoring the mol. structure and copolymer concentration, various self-assembled aggregates were obtained. At a lower concentration, all the copolymers self-assembled into simple vesicles. With increasing the polymer concentration, large compound vesicles were formed. The photo-sensitive properties of the formed aggregates were also studied. Upon irradiation with a polarized light, the aggregates were elongated. Large compound vesicles were found to deform into compact spindles with a very large axial ratio.

Soft Matter published new progress about 135529-02-1. 135529-02-1 belongs to esters-buliding-blocks, auxiliary class azo,Alkenyl,Benzene,Ester,Ether, name is 6-(4-((4-Methoxyphenyl)diazenyl)phenoxy)hexyl methacrylate, and the molecular formula is C18H15N3O3, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Chen, Zhi-Feng published the artcileComparison of the ability of UV-Vis and UPLC-Q-TOF-MS combined with chemometrics to discriminate recycled and virgin polyethylene, Recommanded Product: Ethyl 4-dimethylaminobenzoate, the publication is Journal of Hazardous Materials (2022), 423(Part_B), 127165, database is CAplus and MEDLINE.

A growing attention is attracted to the use of recycled plastics as food contact materials, and its chem. safety research and discrimination approach are indispensable. In current study, UV-visible spectrometry (UV-Vis) and ultra-performance liquid chromatog. quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS) were used to provide spectral and mass fingerprinting for polyethylene (PE). Coupling with chemometrics, two methods were developed to discriminate recycled and virgin PE. UV-Vis combined with chemometrics could be a more accessible, simpler and faster approach. 237-331 nm in UV spectrum was regarded as marker region selected by orthogonal partial least-squares discrimination anal. (OPLS-DA) and the accuracy of both calibration and validation set could reach 100% in linear discrimination anal. (LDA) based on this region. Besides, 2314 ions were detected by UPLC-Q-TOF-MS and processed by MS-DIAL. 48 candidate chems. were identified, including ketone, esters, carboxylic acid, alcs. and phenols, amine, nitriles, aldehydes and others. Possible origins of these compounds could be classified as plastic, food, drug, cosmetics and pesticide related. Many of these compounds are highly toxic, especially pesticide related, indicating that recycling in closed loop or sorting by the recycled plastic articles is very necessary if the recycled PE is going to be used as food contact material.

Journal of Hazardous Materials published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Recommanded Product: Ethyl 4-dimethylaminobenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Gu, Lingwen published the artcileDimethyl itaconate protects against fungal keratitis by activating the Nrf2/HO-1 signaling pathway, Quality Control of 617-52-7, the publication is Immunology & Cell Biology (2020), 98(3), 229-241, database is CAplus and MEDLINE.

Di-Me itaconate (DI) is a membrane-permeable itaconate derivative with anti-inflammatory functions. However, the anti-inflammatory effect of DI has never been studied in fungal keratitis. In this study, we tested the protective effect of DI against fungal keratitis and assessed the role of Nrf2/HO-1 signaling in this process. Eyes of C57BL/6 (B6) mice were treated with 2 mm DI after infection with Aspergillus fumigatus. HCECs were pretreated with 0.25 mm DI and then incubated with A. fumigatus. Clin. scoring, slit-lamp photog., myeloperoxidase determination, flow cytometry and immunostaining were used to assess the disease response and treatment efficacy. PCR, Western blot and ELISA were used to assess the expression of IL-1β, chemokine (C-X-C motif) ligand 1, IL-6, IL-8, Nrf2 and HO-1. In addition, quantification of viable fungi, absorbance assays and fluorimetry were used to measure DI fungistatic activity. We observed that DI-treated eyes showed decreased clin. scores, fungal loads, PMN infiltration and cytokine expression, compared with phosphate-buffered saline-treated infected eyes. Moreover, DI treatment increased Nrf2 and HO-1 expression in corneas and nuclear Nrf2 accumulation in HCECs. Finally, DI treatment reduced the A. fumigatus absorbance and fungal mass. These data indicate that DI protects against fungal keratitis by limiting inflammation via the Nrf2/HO-1 signaling pathway and that DI inhibits the growth of A. fumigatus.

Immunology & Cell Biology published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C7H10O4, Quality Control of 617-52-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics