Month: December 2022

Kesbic, Osman Sabri published the artcileEffects of juniper berry oil on growth performance and blood parameters in common carp (Cyprinus carpio), Related Products of esters-buliding-blocks, the main research area is Cyprinus blood juniper berry oil growth performance.

In this study the effects of com. juniper berry oil (JBO) as a feed additive in diets for common carp (Cyprinus carpio) was investigated in terms of growth performance, feed utilization and blood parameters. The exptl. diets were prepared to contain JBO at rate of 0 (JBO-0), 5 (JBO-5) and 10 (JBO-10) ml/kg. Common carps (3.07 ± 0.15 g) were fed with test diets for a period of 60 days in 40-L aquariums of triplicate groups. The feeding experiment revealed that JBO groups showed significantly better growth performance and feed utilization compared with the control group (JBO-0) (p < 0.05). No significant effect was observed on Hb amount, hematocrit ratio and consequential erythrocyte indexes (p > 0.05). In the JBO groups, serum cholesterol, triglyceride, glutamic-pyruvic transaminase and alk. phosphatase levels decreased significantly (p < 0.05). In contrast, the total protein level showed a significant increase, while glucose, albumin and lactate dehydrogenase levels did not present any significant variation (p > 0.05). Therefore, dietary addition of 5 mL/kg JBO promoted fish growth and pos. influenced the blood parameters in common carps.

Aquaculture Research published new progress about Albumins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Related Products of esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Stojanovic, Nikola M. published the artcileToxic essential oils, part VI: Acute oral toxicity of lemon balm (Melissa officinalis L.) essential oil in BALB/c mice, Recommanded Product: Methyl octanoate, the main research area is Melissa aerial part essential oil oral toxicity; Behavioral alterations; Biochemical parameters; Essential oil; Histopathological changes; Melissa officinalis L. (Lamiaceae); Oral toxicity in mice.

Despite being renowned for its volatiles, the data on the toxicity of the essential oil of lemon balm (Melissa officinalis L., Lamiaceae) is rather limited compared to its solvent/water-soluble extractibles. In this study, the aerial parts essential oil of M. officinalis, with over 130 constituents identified herein, 26 of which detected for the first time, was investigated for acute oral toxicity in BALB/c mice. The oil, composed of predominantly monoterpene aldehydes, citronellal (21.2-21.8%), neral (17.8-18.4%), and geranial (22.9-23.5%), which were assayed in parallel with the oil in some tests, induced significant changes in animal behavior, as well as altered biochem. parameters reflecting liver and kidney functions. Different pathol. changes in the stomach, duodenum, liver, and kidneys were detected when the oil was administered in doses higher than 1 g kg-1. A depletion in the liver/kidney antioxidant capacities and an increased rate of lipid peroxidation was noted for animals treated with lemon balm oil. The calculated value of the oral LD50 in BALB/c mice (2.57 g kg-1) infers that the essential oil is only moderately toxic.

Food and Chemical Toxicology published new progress about Albumins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Recommanded Product: Methyl octanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lubinsky, Anthony Steven published the artcileInhaled pulmonary vasodilators are not associated with improved gas exchange in mechanically ventilated patients with COVID-19: A retrospective cohort study, Safety of 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, the main research area is inhaled pulmonary vasodilator mech ventilation COVID19 population; ARDS; COVID-19; Epoprostenol; Inhaled nitric oxide; Respiratory failure; Ventilatory ratio.

Measure the effect of inhaled pulmonary vasodilators on gas exchange in mech. ventilated patients with COVID-19. A retrospective observational cohort study at three New York University Hospitals was performed including eighty-four mech. ventilated SARS Cov-2 nasopharyngeal PCR pos. patients, sixty nine treated with inhaled nitric oxide (iNO) and fifteen with inhaled epoprostenol (iEPO). The primary outcomes were change in PAO2:FIO2 ratio, oxygenation Index (OI), and ventilatory ratio (VR) after initiation of inhaled pulmonary vasodilators. There was no significant change in PAO2:FIO2ratio after initiation of iNO (mean – 4.1, 95% CI -17.3-9.0, P = 0.54) or iEPO (mean – 3.4, 95% CI -19.7-12.9, P = 0.66), in OI after initiation of iNO (mean 2.1, 95% CI-0.04-4.2, P = 0.054) or iEPO (mean – 3.4, 95% CI -19.7-12.9, P = 0.75), or in VR after initiation of iNO (mean 0.17, 95% CI -0.03-0.36, P = 0.25) or iEPO (mean 0.33, 95% CI -0.0847-0.74, P = 0.11). PAO2:FIO2, OI and VR did not significantly change over a five day period starting the day prior to drug initiation in patients who received either iNO or iEPO assessed with a fixed effects model. Inhaled pulmonary vasodilators were not associated with significant improvement in gas exchange in mech. ventilated patients with COVID-19.

Journal of Critical Care published new progress about Albumins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 55981-09-4 belongs to class esters-buliding-blocks, name is 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, and the molecular formula is C12H9N3O5S, Safety of 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

El Bohi, Khlood M. published the artcileThe efficiency of pomegranate (Punica granatum) peel ethanolic extract in attenuating the vancomycin-triggered liver and kidney tissues injury in rats, Product Details of C23H46O2, the main research area is Punica peel extract liver kidney injury vancomycin; BCL-2; C-reactive protein; Caspase-3; Punica granatum; Rat; Vancomycin.

Abstract: This study evaluated the potential of Punica granatum peel ethanol extract (PPEE) in attenuating the liver and kidney tissue injury induced by vancomycin (VM) treatment in rats. Fifty rats were distributed equally into five groups: control group, PPEE-administered group (100 mg/kg BW/day for 2 wk; orally), VM-treated group (443.6 mg/kg BW, every alternate day for 2 wk; i.p.), pre-treated group, and concomitant-treated group. The biochem. response and the histopathol. of the hepatic and renal tissue of the treated animals were assessed. The results showed that VM treatment induced substantial hepatotoxicity and nephrotoxicity, evidenced by a significant elevation in tissue injury and lipid oxidative (malondialdehyde) and inflammatory response (C-reactive protein) biomarkers, with lowered antioxidants and protein levels. Addnl., VM treatment induced various morphol., cytotoxic, vascular, and inflammatory perturbations as well as upregulation in the immune-expression of Caspase-3 and downregulation of BCL-2. Moreover, PPEE co-treatment was found to reduce the VM-induced toxicity by protecting the tissue against reactive oxygen species (ROS)-mediated oxidative damage, and inflammation as well as hinder the apoptotic cell death by modulating the expression of apoptosis-related proteins. Thus, we conclude that the PPEE administration showed more restoring efficacy when administered prior to VM medication.

Environmental Science and Pollution Research published new progress about Albumins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 929-77-1 belongs to class esters-buliding-blocks, name is Methyl docosanoate, and the molecular formula is C23H46O2, Product Details of C23H46O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sherif, Arsia Tarnam Yakoob published the artcileIn vitro evaluation of purple inflorescence of Gomphrena globosa (L.) extracts for antiinflammatory activity and its GC/MS profile, Formula: C11H22O2, the main research area is Gomphrena globosa purple inflorescence extract antiinflammatory activity GC MS.

The complex biol. process that protects the body by triggering immune system for infection, injury or disease is called inflammation. When compared with acute inflammation, chronic inflammation lasts for weeks, months or years and cause tissue damage. Non-steroidal antiinflammatory drugs play an important role in reducing pain and inflammation by blocking arachidonic acid metabolism through cyclooxygenase enzyme and thereby reducing the production of prostaglandins. Due to severe side effects associated with non-steroidal anti-inflammatory drug, many researchers are focusing on plant secondary metabolite with no or less side effects. In Trinidad, Globe Amaranth is used to treat several ailments for scientific validation of the folklore claim of this plant the present study was conducted. Decoction and hydroalcoholic flower extracts (pink varieties) of G. globosa was evaluated for its anti-inflammatory activity. Albumin denaturation method, anti-proteinase action, HRBC membrane stabilization and protein denaturation methods were carried out. Aspirin and diclofenac sodium were used as standard drug. The results showed that decoction extract inhibited heat induced protein denaturation (p≤0.05), inhibited proteinase action and heat induced hemolysis of erythrocyte at 500μg/mL. Hypo tonicity induced hemolysis was also found to be significant with 68.42% of inhibition (p ≤0.05). The total phenol in decoction extract was 60mcg/mL and reducing power assay revealed significant antioxidant activity. The identification of bioactive compounds in hydroalcoholic extract was done using GC-MS. Earlier reports have showed that the compound 1, 2-benzenedicarboxylic acid, bis (2-ethylhexyl) ester possess antioxidant and anti-inflammatory activity. From the results, the decoction extract possess does dependent potent anti-inflammatory activity. This was plausibly due to phytoconstituents that acted individually or synergistically in exhibiting the potent activity.

Asian Journal of Biological and Life Sciences published new progress about Albumins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 110-42-9 belongs to class esters-buliding-blocks, name is Methyl decanoate, and the molecular formula is C11H22O2, Formula: C11H22O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Azeem, Manal N. Abdel published the artcileIn vitro antioxidant, anticancer, anti-inflammatory, anti-diabetic and anti-Alzheimer potentials of innovative macroalgae bio-capped silver nanoparticles, Quality Control of 110-42-9, the main research area is silver nanoparticle delivery antioxidant anticancer antiinflammatory antidiabetic antialzheimer cancer; Biological activities; Enteromorpha flexuosa; Galaxaura elongate; Turbinaria ornata.

The antagonistic side effects of chem. medications led to the search for safe strategies such as biogenic agents. Correspondingly, this study aims to create biogenic, appropriate, auspicious and innovative therapeutic agents like Galaxaura elongata {GE}, Turbinaria ornata {TO} and Enteromorpha flexuosa {EF} macroalgae-based silver nanoparticles (Ag-NPs). The Ag+ reduction and the creation of Ag[GE]-NPs, Ag[TO]-NPs and Ag[EF]-NPs have been validated using UV-visible spectroscopy, Fourier transform IR spectroscopy (FTIR), scanning electron microscope (SEM) and ζ potential anal., and the chem. composition of macroalgae crude extracts was estimated through gas chromatog.-mass spectrometry (GC-MS). Further, macroalgae-based Ag-NPs were tested for their free radical scavenging activity DPPH, ABTS, anticancer activity in human liver carcinoma (HepG2) cell line, distinctive inflammation forms and elevated α-amylase. Results showed that the biosynthesized Ag-NPs have unique mech. and physicochem. characters attributed to their high relative surface area, nanosized dimensions and spherical shape. At dose of 200 μg/mL, the DPPH radical scavenging capacity was maximized with Ag[TO]-NPs (67.26%); however, Ag[EF]-NPs was the most potent as ABTs scavenger (97.74%). Addnl., Ag[GE]-NPs had the maximum proteinase inhibitory action with 59.78%. The 1000 μg/mL of Ag[GE]-NPs, Ag[TO]-NPs and Ag[EF]-NPs revealed significant inhibitions of cell growth of HepG2 resulting in cell viabilities 5.92%, 4.44% and 11.33%, resp. These findings suggest that macroalgae bio-capped Ag-NPs have magnificent biol. potentials for safe biomedical applications.

Environmental Science and Pollution Research published new progress about Albumins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 110-42-9 belongs to class esters-buliding-blocks, name is Methyl decanoate, and the molecular formula is C11H22O2, Quality Control of 110-42-9.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yang, Yurong published the artcileEffects of the proteins of indica rice and indica waxy rice on the formation of volatiles of sweet rice wine, Formula: C10H20O2, the main research area is proteins indica waxy formation volatiles sweet rice wine.

The proteins in the raw materials affect the formation of flavor during fermentation Among all the fermentation broth of protein fraction in the study, the rice prolamin and albumin effectively promoted floral, honey and fruity characteristics in fermentation with higher level of β-phenylethyl alc., 2,4-dimethyl-benzaldehyde and Et hexadecanoate than those in the fermentation of globulin and glutelin; albumin is with higher level of higher alcs., but higher alcs. are not good for health because of their acute toxicity and neurotoxic effects. In a further fermentation experiment of addition of prolamin, extra prolamin significantly promoted the formation of aroma volatiles, especially medium and long fatty acid esters and β-phenylethyl alc. and its acetate, and the content of β-phenethyl acetate in sweet rice wine with added prolamin was more than twice that of single sweet rice wine. This study demonstrates that the different rice protein components significantly affect the volatiles generated by microorganism metabolism to impact the flavor of sweet rice wine, and the flavor quality of sweet rice wine can be enhanced by increasing the prolamin content.

International Journal of Food Science and Technology published new progress about Albumins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 106-32-1 belongs to class esters-buliding-blocks, name is Ethyl octanoate, and the molecular formula is C10H20O2, Formula: C10H20O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yang, Yurong published the artcileEffects of the proteins of indica rice and indica waxy rice on the formation of volatiles of sweet rice wine, Formula: C17H34O2, the main research area is proteins indica waxy formation volatiles sweet rice wine.

The proteins in the raw materials affect the formation of flavor during fermentation Among all the fermentation broth of protein fraction in the study, the rice prolamin and albumin effectively promoted floral, honey and fruity characteristics in fermentation with higher level of β-phenylethyl alc., 2,4-dimethyl-benzaldehyde and Et hexadecanoate than those in the fermentation of globulin and glutelin; albumin is with higher level of higher alcs., but higher alcs. are not good for health because of their acute toxicity and neurotoxic effects. In a further fermentation experiment of addition of prolamin, extra prolamin significantly promoted the formation of aroma volatiles, especially medium and long fatty acid esters and β-phenylethyl alc. and its acetate, and the content of β-phenethyl acetate in sweet rice wine with added prolamin was more than twice that of single sweet rice wine. This study demonstrates that the different rice protein components significantly affect the volatiles generated by microorganism metabolism to impact the flavor of sweet rice wine, and the flavor quality of sweet rice wine can be enhanced by increasing the prolamin content.

International Journal of Food Science and Technology published new progress about Albumins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 41114-00-5 belongs to class esters-buliding-blocks, name is Ethyl pentadecanoate, and the molecular formula is C17H34O2, Formula: C17H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Alghamdi, Saleh B. published the artcileAssessment of antioxidant, antimicrobial, cytotoxic activities and isolation of some chemical constituents from different extracts of Pergularia daemia, Quality Control of 929-77-1, the main research area is Pergularia extract antioxidant antimicrobial agent cytotoxicity.

Pergularia demia is a wild plant growing in Albaha region. This study aimed to investigate some chem. constituents of P. demia and their biol. activities. The aerial parts of P. demia were extracted with water and organic solvents (chloroform, Et acetate, butanol, methanol, and petroleum ether). The chem. constituents of the unsaponifiable and the fatty acid fractions were identified using GC-MS analyses. The Et acetate and n-butanol extracts were subjected to chromatog. techniques. Total phenolic and flavonoid contents in the extracts were determined using colorimetric assay. The antioxidant activity was determined using 1,1-diphenyl-2-picrylhydrazyl free radical scavenging assay. The antimicrobial activity was evaluated using the modified Kirby-Bauer disk-diffusion method while the cytotoxic activity was evaluated using HepG-2 and HCT-116 cancer cell lines. Chromatog. separation of the Et acetate and n-butanol extracts afforded five flavonoidal compounds; apigenin, chyrsoeriol, quercetin, vitexin and lucenin-2.The total phenolic content of the extract ranged from 15.14 ± 0.02 to 39.33 ± 0.17 mg GAE/g. The Et acetate extract had the highest total flavonoid content (76.11 ± 0.16 mg QE/g) and the highest antioxidant activity (93.95%). The extracts showed varied degrees of inhibition against tested strains with the Et acetate extract having the maximum inhibition zone (17 to 23 mm against Staphylococcus aureus and Bacillus subtilis). The Et acetate extract showed a strong cytotoxicity activity against HEPG2 and HCT-116 cancer cell lines with IC50 values of 1.62 μg/mL and 2.48 μg/mL, resp. This is the first report of the isolation of the five flavonoidal compounds from P. demia. The plant has potential as antioxidant, antibacterial, and cytotoxic agents.

Tropical Journal of Natural Product Research published new progress about Aglycons Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 929-77-1 belongs to class esters-buliding-blocks, name is Methyl docosanoate, and the molecular formula is C23H46O2, Quality Control of 929-77-1.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Marullo, Philippe published the artcileMetabolic, organoleptic and transcriptomic impact of Saccharomyces cerevisiae genes involved in the biosynthesis of linear and substituted esters, HPLC of Formula: 106-32-1, the main research area is Saccharomyces metabolism organoleptic transcriptomic biosynthesis; MGL2; YJU3; histone acetylation; substituted ester metabolism; wine fermentation.

Esters constitute a broad family of volatile compounds impacting the organoleptic properties of many beverages, including wine and beer. They can be classified according to their chem. structure. Higher alc. acetates differ from fatty acid Et esters, whereas a third group, substituted Et esters, contributes to the fruitiness of red wines. Derived from yeast metabolism, the biosynthesis of higher alc. acetates and fatty acid Et esters has been widely investigated at the enzymic and genetic levels. As previously reported, two pairs of esterases, resp. encoded by the paralogue genes ATF1 and ATF2, and EEB1 and EHT1, are mostly involved in the biosynthesis of higher alc. acetates and fatty acid Et esters. These esterases have a moderate effect on the biosynthesis of substituted Et esters, which depend on mono-acyl lipases encoded by MGL2 and YJU3. The functional characterization of such genes helps to improve our understanding of substituted ester metabolism in the context of wine alc. fermentation In order to evaluate the overall sensorial impact of esters, we attempted to produce young red wines without esters by generating a multiple esterase-free strain (δatf1, δatf2, δeeb1, and δeht1). Surprisingly, it was not possible to obtain the deletion of MGL2 in the δatf1/δatf2/δeeb1/δeht1 background, highlighting unsuspected genetic incompatibilities between ATF1 and MGL2. A preliminary RNA-seq anal. depicted the overall effect of the δatf1/δatf2/δeeb1/δeht1 genotype that triggers the expression shift of 1124 genes involved in nitrogen and lipid metabolism, but also chromatin organization and histone acetylation. These findings reveal unsuspected regulatory roles of ester metabolism in genome expression for the first time.

International Journal of Molecular Sciences published new progress about Acetates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 106-32-1 belongs to class esters-buliding-blocks, name is Ethyl octanoate, and the molecular formula is C10H20O2, HPLC of Formula: 106-32-1.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics