Month: December 2022

Bruna-Maynou, Fernanda J. published the artcileFlavored Sherry vinegar with citric notes: Characterization and effect of ultrasound in the maceration of orange peels, Safety of Methyl decanoate, the main research area is Citrus sherry vinegar isobutyl acetate carvone ultrasound food product; Orange peel; Sensory analysis, GC-O; Sherry vinegar; Ultrasounds; Volatile compounds.

Accelerated maceration experiments of orange peels in Sherry vinegar employing ultrasounds (US) have been carried out. Their effect on the vinegars volatile composition as well as on its olfactometric and sensory characteristics have been evaluated. The optimal conditions for the ultrasounds were determined as follows: sonication power 550 W/L; pulses 40 s On and 20 s Off; with orange peel 200 g/L established previously. Statistical studies showed that maceration under ultrasounds increased volatile compounds content, since the vinegars obtained showed a high content in alcs., aldehydes and terpenes. Regarding the olfactometric study, the control vinegar exhibited the lowest values for the “”floral””, “”greasy”” or “”citric”” categories and the highest value for the “”sweet”” category, whereas the US macerated vinegars presented the highest and lowest values for the “”floral”” and the “”acid”” categories, resp. Based on their sensory evaluation, the panel members preferred the vinegar where orange peels had macerated under ultrasounds for 90 min. According to the results, ultrasound is a technol. that could be employed to broaden the range of products manufactured by Sherry vinegar producers.

Food Research International published new progress about Citrus sinensis. 110-42-9 belongs to class esters-buliding-blocks, name is Methyl decanoate, and the molecular formula is C11H22O2, Safety of Methyl decanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bruna-Maynou, Fernanda J. published the artcileFlavored Sherry vinegar with citric notes: Characterization and effect of ultrasound in the maceration of orange peels, Application of Ethyl 3-hydroxybutanoate, the main research area is Citrus sherry vinegar isobutyl acetate carvone ultrasound food product; Orange peel; Sensory analysis, GC-O; Sherry vinegar; Ultrasounds; Volatile compounds.

Accelerated maceration experiments of orange peels in Sherry vinegar employing ultrasounds (US) have been carried out. Their effect on the vinegars volatile composition as well as on its olfactometric and sensory characteristics have been evaluated. The optimal conditions for the ultrasounds were determined as follows: sonication power 550 W/L; pulses 40 s On and 20 s Off; with orange peel 200 g/L established previously. Statistical studies showed that maceration under ultrasounds increased volatile compounds content, since the vinegars obtained showed a high content in alcs., aldehydes and terpenes. Regarding the olfactometric study, the control vinegar exhibited the lowest values for the “”floral””, “”greasy”” or “”citric”” categories and the highest value for the “”sweet”” category, whereas the US macerated vinegars presented the highest and lowest values for the “”floral”” and the “”acid”” categories, resp. Based on their sensory evaluation, the panel members preferred the vinegar where orange peels had macerated under ultrasounds for 90 min. According to the results, ultrasound is a technol. that could be employed to broaden the range of products manufactured by Sherry vinegar producers.

Food Research International published new progress about Citrus sinensis. 5405-41-4 belongs to class esters-buliding-blocks, name is Ethyl 3-hydroxybutanoate, and the molecular formula is C6H12O3, Application of Ethyl 3-hydroxybutanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Guleria, Niraj published the artcileIdentification of male-specific active host plant volatiles for maize stem borer, Chilo partellus swinhoe, HPLC of Formula: 140-11-4, the main research area is male specific host plant volatiles maize stem borer Chilo.

The present study was conducted to identify male-specific active plant volatiles from maize against Chilo partellus. The gas chromatog.-electroantennogram detector evaluation of volatile extracts collected from maize plant through dynamic headspace collection revealed the presence of six electrophysiol. active volatiles for male, viz. toluene, 2-ethyl-1-hexanol, 4- hydroxy-4-methyl-2-pentanone, 1,4-dichlorobenzene, p- iso-Pr benzaldehyde (cuminaldehyde) and p-xylene. Electroantennogram anal. of selective synthetic volatiles against male moths revealed significantly higher response to geranyl acetate, cuminaldehyde, linalool and 2-ethyl-1-hexanol. Electroantennogram studies showed dose-dependent responses of male moths against geranyl acetate, cuminaldehyde, linalool and 2-ethyl-1-hexanol up to 50μg, above which saturation of antennal response was noticed. These findings will help to study the synergistic activity of identified volatiles with pheromone compounds for developing more effective lure for C. partellus monitoring and mass trapping.

Current Science published new progress about Chilo partellus. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, HPLC of Formula: 140-11-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Shrestha, Shyam Sharan published the artcilePhytochemical Investigations and In Vitro Bioactivity Screening on Melia azedarach L. Leaves Extract from Nepal, Synthetic Route of 110-42-9, the main research area is Melia leaf phytochem compound bioactivity; Melia azedarach; enzyme inhibitory assays; phytosterols; polyphenols; traditional Nepalese medicine.

Melia azedarach is a common tree used in the traditional medicine of Nepal. In this work, leaves were considered as source of bioactive constituents and composition of methanol extract was evaluated and compared with starting plant material. Flavonoid glycosides and limonoids were identified and quantified by HPLC-DAD-MSn approaches in dried leaves and methanolic extract, while HPLC-APCI-MSn and GC/MS anal. were used to study phytosterol and lipid compositions β-Sitosterol and rutin were the most abundant constituents. HPLC-APCI-MSn and HPLC-DAD-MSn anal. revealed high levels of phytosterols and flavonoids in methanolic extract accounting 9.6 and 7.5% on the dried weight, resp. On the other hand, HPLC/MSn data revealed that limonoid constituents were in minor amount in the extract <0.1%, compared with leaves (0.7%) indicating that degradation occurred during extraction or concentration procedures. The methanol extract was subjected to different bioassays, and antioxidant activity was evaluated. Limited inhibitory activity on acetyl and butyryl cholinesterase, as well as on amylase were detected. Moreover, tyrosinase inhibition was significant resulting in 131.57±0.51 mg kojic acid equivalent/g of dried methanol extract, suggesting possible use of this M. azedarach extract in skin hyperpigmentation conditions. Moderate cytotoxic activity, with IC50 of 26.4μg/mL was observed against human ovarian cancer cell lines (2008 cells). Our findings indicate that the Nepalese M. azedarach leaves can be considered as valuable starting material for the extraction of phenolics and phytosterols, yielding extracts with possible cosmetic and pharmaceutical applications. Chemistry & Biodiversity published new progress about Cell morphology. 110-42-9 belongs to class esters-buliding-blocks, name is Methyl decanoate, and the molecular formula is C11H22O2, Synthetic Route of 110-42-9.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Honghai published the artcilePreparation and Application of Magnetic Nano-Solid Acid Catalyst Fe3O4-PDA-SO3H, Safety of Ethyl 4-oxopentanoate, the main research area is iron oxide polydopamine sulfonic acid magnetic nanosolid catalyst.

A magnetic nano-solid acid catalyst Fe3O4-PDA-SO3H was synthesized through an efficient method, as an eco-friendly and more efficient catalyst. The obtained catalyst has uniform core-shell structure, appropriate particle size, and high acid d. Fe3O4-PDA-SO3H was applied to catalyze the esterification of levulinic acid (LA) with alcs. of different chain length to produce the levulinate esters. The catalytic effect was optimized from the aspects of catalyst dosage, reaction temperature, and acid-alc. molar ratio. Furthermore, the response surface optimization method was used to obtain the optimal conditions. Verified under these conditions, the exptl. results showed that the conversion rate of LA can reach 95.87%, which was much higher than common cationic exchange resin Amberlyst 36 and Amberlyst 46. Furthermore, the recovery and reuse of the Fe3O4-PDA-SO3H was demonstrated six times without obvious loss in the activity.

Energies (Basel, Switzerland) published new progress about Cation exchange. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Safety of Ethyl 4-oxopentanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yang, Xiaoqiu published the artcileNon-targeted screening and analysis of volatile organic compounds in drinking water by DLLME with GC-MS, Application In Synthesis of 110-42-9, the main research area is volatile organic compound drinking water analysis DLLME GC MS; Dispersive liquid-liquid microextraction; Drinking water; In silico toxicity prediction; Non-targeted analysis; Volatile organic compound.

Volatile organic compounds (VOCs) in drinking water may potentially be hazardous. We developed a novel non-targeted anal. method of VOCs in drinking water that uses dispersive liquid-liquid microextraction coupled with gas chromatog.-mass spectrometry. Anal. parameters were selected from range-finding tests on the peak number and average area of the extracted compounds The optimized method was applied to analyze VOCs in tap water samples collected from Wuhan City, China. Twenty-seven compounds with high match degrees and a high prevalence were selected for quantification and evaluation. We used structure-activity relationships to predict the carcinogenicity of these compounds Although most of the compounds were non-toxic, compounds such as di-Bu phthalate and diacetone alc. should be investigated further. Untargeted anal. of the tap water samples identified 75-200 VOCs, including 67 highly prevalent compounds Industrial and pharmaceutical chems. accounted for approx. 70% of the VOCs in the samples. This method of non-targeted anal. and in silico toxicity prediction is simple and economic, and could be used in screening VOCs in drinking water.

Science of the Total Environment published new progress about Carcinogenicity. 110-42-9 belongs to class esters-buliding-blocks, name is Methyl decanoate, and the molecular formula is C11H22O2, Application In Synthesis of 110-42-9.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sinha, Meetali published the artcileGenotoxicity QSAR (Geno-QSAR) models for the safety prioritization of specialty chemicals, Recommanded Product: Benzyl acetate, the main research area is genotoxicity quant structure activity relationship safety.

Toxicity profiling of specialty chems. is essential, since several studies have reported their role in acute/chronic health effects. It is voluminous to perform a battery of toxicity experiments on available specialty chems. In this study, we employed robust QSAR approaches to predict the carcinogenicity and mutagenicity potential for a dataset of 131 specialty chems. utilizing machine learning tools. Four predictive approaches were selected to benchmark the reliability and applicability of the suitable genotoxicity QSAR (Geno-QSAR) models each for carcinogenicity (CAESAR, ISS, ANTARES, and ISSCAN) and mutagenicity (CAESAR, SARpy, ISS, and KNN). Five-fold statistical evaluation was performed using an external dataset of more than 2000 compounds with their known genotoxicity potential. KNN/Read across and IRFMN/ANTARES resulted as the best model for mutagenicity and carcinogenicity, resp. Results obtained from the selected predictive models are narrowed down to the potentially safe compounds and are cross-validated with the exptl. details compiled through the literature mining. Geno-QSAR approaches demonstrated in this investigation have widespread applicability for safe compound prioritization and toxicity prediction of a large number of chems. in a lucid way.

Journal of the Indian Chemical Society published new progress about Carcinogenicity. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Recommanded Product: Benzyl acetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pleasants, Roy A. published the artcileGlycopyrrolate/eFlow CS: The First Nebulized Long-Acting Muscarinic Antagonist Approved to Treat Chronic Obstructive Pulmonary Disease, Synthetic Route of 142-90-5, the main research area is review chronic obstructive pulmonary disease glycopyrrolate LAMA nebulizer; anticholinergics; bronchodilators; chronic obstructive pulmonary disease; drug development and approval; inhalers; pharmaceutical care.

Objective: To review the pharmacol., efficacy, and safety of the first nebulized long-acting muscarinic antagonist (LAMA), glycopyrrolate (GLY)/eFlow closed system (CS) nebulizer, approved for maintenance treatment of chronic obstructive pulmonary disease (COPD). Data Sources: A PubMed search was conducted (Jan. 2000 to July 2018) using the following terms/phrases: nebulized glycopyrrolate, inhalation devices in COPD, long-acting muscarinic antagonists COPD, and COPD survey. Retrieved articles were reviewed to identify addnl. references Study Selection and Data Extraction: Primary and review articles on GLY/eFlow CS and other treatment options for patients with COPD were selected. Data Synthesis: Guidelines recommend the use of LAMAs, alone or in combination with long-acting β2-agonists, as maintenance therapy for the majority of patients with COPD. With the range of different devices and bronchodilators now available, treatment can be tailored based on individual needs. The eFlow CS nebulizer delivers GLY rapidly over a 2- to 3-min period and provides bronchodilation within 30 min, lasting 12 h. Phase 2 dose-finding and phase 3 studies demonstrated sustained statistically significant and clin. important improvements in pulmonary function and patient-reported outcomes with GLY/eFlow CS. Relevance to Patient Care and Clin. Practice: GLY/eFlow CS provides a novel, portable, efficient, and rapid drug delivery system. Conclusions: The recently approved GLY/eFlow CS drug-device combination provides a viable treatment option for patients with COPD, particularly those with conditions that may impair proper use of traditional handheld inhalers.

Annals of Pharmacotherapy published new progress about Bronchodilators. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, Synthetic Route of 142-90-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Huang, Yaling published the artcileVariation of Volatile Compounds and Corresponding Aroma Profiles in Chinese Steamed Bread by Various Yeast Species Fermented at Different Times, Application of Benzyl acetate, the main research area is volatile aroma Chinese steamed bread yeast; Chinese steamed bread; GC−MS; GC−O; aroma-active compounds; sensory evaluation.

To control the fermentation process of yeast-Chinese steamed bread (CSB), the volatile compounds and odor profiles of yeast-CSBs during fermentation were comprehensively investigated by sensory evaluation, gas chromatog.-mass spectrometry, gas chromatog.-olfactometry (GC-O), and odor activity value (OAV). Eight sensory attributes were established, and quant. descriptive anal. results showed that CF1303-CSB had intense sweet and sweet aftertaste attributes, CF1318-CSB was characterized by milky, wheaty, and yeasty attributes, while CL10138-CSB presented distinct sour, winy, and floury attributes. A total of 41 key aroma-active compounds were detected, and phenylethyl alc. was the most potent aroma compound with a flavor dilution (FD) of 1024. CF1303-CSB, CF1318-CSB, and CL10138-CSB contained 24, 22, and 21 key aroma compounds, resp., based on the OAV. These key aroma compounds can be used as the potential markers to monitor the yeast-CSBs during the fermentation process. Five compounds, including β-myrcene, 2-phenoxyethanol, Me cinnamate, guaiacol, and o-cresol, were first identified in CSB. These results provide theor. basis for processing and quality control of yeast-CSBs.

Journal of Agricultural and Food Chemistry published new progress about Bread (steamed). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Application of Benzyl acetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

El Majdoub, Yassine Oulad published the artcileChemical characterization of three accessions of Brassica juncea L. extracts from different plant tissues, Application In Synthesis of 111-11-5, the main research area is chem composition root stem leaf Brassica; Brassica juncea spp.; GC; HPLC; foods; metabolites; non-volatile; nutraceuticals; volatile.

Indian mustard or Brassica juncea (B. juncea) is an oilseed plant used in many types of food (as mustard or IV range salad). It also has non-food uses (e.g., as green manure), and is a good model for phytoremediation of metals and pesticides. In recent years, it gained special attention due to its biol. compounds and potential beneficial effects on human health. In this study, different tissues, namely leaves, stems, roots, and flowers of three accessions of B. juncea: ISCI 99 (Sample A), ISCI Top (Sample B), and “”Broad-leaf”” (Sample C) were analyzed by HPLC-PDA/ESI-MS/MS. Most polyphenols identified were bound to sugars and phenolic acids. Among the three cultivars, Sample A flowers turned were the richest ones, and the most abundant bioactive identified was represented by Isorhamnetin 3,7-diglucoside (683.62 μg/100 mg dry weight (DW) in Sample A, 433.65 μg/100 mg DW in Sample B, and 644.43 μg/100 mg DW in Sample C). In addition, the most complex samples, viz. leaves were analyzed by GC-FID/MS. The major volatile constituents of B. juncea L. leaves extract in the three cultivars were benzenepropanenitrile (34.94% in Sample B, 8.16% in Sample A, 6.24% in Sample C), followed by benzofuranone (8.54% in Sample A, 6.32% in Sample C, 3.64% in Sample B), and phytone (3.77% in Sample B, 2.85% in Sample A, 1.01% in Sample C). The overall evaluation of different tissues from three B. juncea accessions, through chem. anal. of the volatile and non-volatile compounds, can be advantageously taken into consideration for future use as dietary supplements and nutraceuticals in food matrixes.

Molecules published new progress about Brassica juncea. 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Application In Synthesis of 111-11-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics