Month: December 2022

Kazlauskiene, Daiva published the artcileDetermination of fatty acid composition and antioxidant activity in vegetable oils, Product Details of C9H18O2, the main research area is linoleic fatty acid vegetable oil antioxidant activity.

Studies of the composition of vegetable oils are expedient in order to achieve quality product modeling. The goal of this research was to determine the composition of fatty acids using gas chromatog. (GC) and antioxidant activity using DPPH and ABTS spectrophotometric methods. Analyzed oils were castor seed, sunflower seed, sesame seed, fibrous hemp seed, black radish seed and olive oils. Different classes of fatty acids were determined: polyunsaturated, monounsaturated and saturated; omega-3, omega-6 and omega-9 acids and individual constituents. The study results showed that the dominant acids in all oils were oleic and linoleic fatty acids. The best ratio of omega-6 to omega-3 acids was found in fibrous hemp seed oil -3:1. All analyzed vegetable oils demonstrated a high antioxidant activity.

Chemija published new progress about Antioxidants. 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Product Details of C9H18O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Szymanski, Marcin published the artcileComparison of the Chemical Composition and Antioxidant Activity of Essential Oils from the Leaves and Flowers of Sambucus nigra, Safety of Methyl docosanoate, the main research area is antioxidant essential oil leaf flower Sambucus.

Essential oils of Sambucus nigra were obtained by hydrodistillation and analyzed using the GC-MS technique, which led to the identification and quantification of 66 components from the leaves and 74 components from the flowers, accounting for 94.0 and 96.4% of the total components, resp. The main class of compounds present in the leaves were fatty acids and their derivatives: Me linoleate, palmitic acid, hydrocarbon tritetracontane, and an aromatic compound benzoic aldehyde. In the flowers there were hydrocarbons: tritetracontane and n-hexatriacontane, fatty acids and their derivatives: palmitic acid and linoleic acid, and alcs.: 2-methyl-3,15-octadecadienol and 2-hexyl-1-octanol. Among the dominant components of the essential oil of S. nigra flowers, there were also monoterpenes such as rose oxide, epoxylinalol, while the essential oil of the leaves contained a few compounds of monoterpenes in small amounts such as β-pinene and α-pinene. Antioxidant activity of the obtained essential oils was determined by the FRAP and DPPH assay techniques.

Pharmaceutical Chemistry Journal published new progress about Antioxidants. 929-77-1 belongs to class esters-buliding-blocks, name is Methyl docosanoate, and the molecular formula is C23H46O2, Safety of Methyl docosanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mostofa, Mohammad Golam published the artcileStrigolactones regulate arsenate uptake, vacuolar-sequestration and antioxidant defense responses to resist arsenic toxicity in rice roots, Recommanded Product: 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate, the main research area is strigolactone antioxidant defense response arsenic toxicity rice root; Arsenic toxicity; Glutathione metabolism; Oxidative stress; Phosphate transporters; Rice; Strigolactones.

We explored genetic evidence for strigolactonesâ€?role in rice tolerance to arsenate-stress. Comparative analyses of roots of wild-type (WT) and strigolactone-deficient mutants d10 and d17 in response to sodium arsenate (Na2AsO4) revealed differential growth inhibition [WT (11.28%) vs. d10 (19.76%) and d17 (18.03%)], biomass reduction [(WT (33.65%) vs. d10 (74.86%) and d17 (60.65%)] and membrane damage (WT < d10 and d17) at 250 μM Na2AsO4. Microscopic and biochem. analyses showed that roots of WT accumulated lower levels of arsenic and oxidative stress indicators like reactive oxygen species and malondialdehyde than those of strigolactone-deficient mutants. qRT-PCR data indicated lower expression levels of genes (OsPT1, OsPT2, OsPT4 and OsPT8) encoding phosphate-transporters in WT roots than mutant roots, explaining the decreased arsenate and phosphate uptake by WT roots. Increased levels of glutathione and OsPCS1 and OsABCC1 transcripts indicated an efficient vacuolar-sequestration of arsenic in WT roots. Furthermore, higher activities (transcript levels) of SOD (OsCuZnSOD1 and OsCuZnSOD2), APX (OsAPX1 and OsAPX2) and CAT (OsCATA) corresponded to lower oxidative damage in WT roots compared with strigolactone-mutant roots. Collectively, these results highlight that strigolactones are involved in arsenic-stress mitigation by regulating arsenate-uptake, glutathione-biosynthesis, vacuolar-sequestration of arsenic and antioxidant defense responses in rice roots. Journal of Hazardous Materials published new progress about Antioxidants. 2044-85-1 belongs to class esters-buliding-blocks, name is 2',7'-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl diacetate, and the molecular formula is C24H14Cl2O7, Recommanded Product: 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tandee, Kanokwan published the artcileAntioxidant activities and volatile compounds in longan (Dimocarpus longan Lour.) wine produced by incorporating longan seeds, Synthetic Route of 5405-41-4, the main research area is Dimocarpus Saccharomyces antioxidant volatile compound wine seed fermentation temperature; 2,3-Butylene glycol (PubChem CID: 262); 4-Hydroxyphenethyl alcohol (PubChem CID: 10393); 5-Hydroxymethyl-2-furaldehyde (PubChem CID: 237332); Antioxidant; Ethyl hydrogen succinate (PubChem CID: 70610); Longan wine; Phenethyl alcohol (PubChem CID: 6054); Seed; Volatile compound.

The seeds of dried longan, one of the major processed fruits in Thailand, contain several bioactive compounds In this study, we developed longan wine by incorporating its seeds during juice preparation and evaluated the antioxidant activities and volatile compounds in different conditions. The results suggested that Saccharomyces cerevisiae EC-1118 was suitable for fermentation of longan juice supplemented with 50% seed and 20% initial soluble solids at an optimal temperature of 30°C. Different yeast strains showed various extents of antioxidant activities; however, the fermentation temperature and initial soluble solids of longan juice had little effect on the inhibition of reactive species. Antioxidant activities were significantly increased with increasing seed content. Dominant volatile compounds, which were independent of the winemaking conditions, were found to be phenethyl alc., 2,3-butylene glycol, 5-hydroxymethyl-2-furaldehyde, Et hydrogen succinate, and 4-hydroxyphenethyl alc. These compounds highly influenced the antioxidant activities of longan wine produced by incorporating the seeds.

Food Chemistry published new progress about Antioxidants. 5405-41-4 belongs to class esters-buliding-blocks, name is Ethyl 3-hydroxybutanoate, and the molecular formula is C6H12O3, Synthetic Route of 5405-41-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chen, Rong-Fu published the artcileSuppression of Oxygen Radicals Protects Diabetic Endothelium Damage and Tissue Perfusion in a Streptozotocin-Induced Diabetes Rodent Model, Computed Properties of 2044-85-1, the main research area is diabetic endothelium damage tissue perfusion streptozotocin.

Oxygen free radicals play a central role in diabetic angiopathy. This study investigated whether suppression of oxygen radicals could decrease endothelial damage and increase peripheral tissue circulation in a diabetic rodent model. Sprague-Dawley rats were treated using streptozotocin to induce diabetes. The experiments were performed 4 wk after diabetes induction: group 1: control, consisted of normal rats; group 2: diabetes, did not receive treatment; groups III (SOD10) and IV (SOD50): diabetes, received polyethylene glycol-conjugated superoxide dismutase (SOD), an antioxidant, 10 and 50 U/kg per day i.p. for 4 wk. Each subgroup consisted of 10 rats. Oxygen radicals in blood mononuclear cells were detected by flow cytometry. The blood lipid peroxidation byproduct malondialdehyde was measured. Tissue perfusion of hind limb was examined by laser Doppler. The expressions of oxygen radicals, as demonstrated by 8-hydroxyguanosine (8-OG), and constitutive endothelial nitric oxide synthase in distal femoral vessels were examined by immunohistochem. staining. Oxygen radicals, as demonstrated by H2O2 with 2′,7′-dichlorofluorescin diacetate-conjugated expression, were significantly increased in diabetic rats. However, the SOD treatment groups significantly suppressed the H2O2 reaction. Diabetic-induced high malondialdehyde levels were significantly suppressed in the SOD50 group. The topical tissue blood perfusion was significantly increased as detected by laser Doppler in SOD10 and SOD50 groups, as compared with that in diabetes without treatment group (P < 0.05). The expression of 8-OG was markedly increased in the diabetic endothelium and subintima compared with that in normal vessels. Polyethylene glycol-conjugated SOD significantly suppressed 8-OG expression and protected endothelial nitric oxide synthase expression. Suppression of oxygen radicals, particularly with the higher dosage of polyethylene glycol-conjugated SOD at 50 U/kg per day, could have a pos. effect to protect against endothelial damage and enhance peripheral perfusion in diabetes. Annals of Plastic Surgery published new progress about Antioxidants. 2044-85-1 belongs to class esters-buliding-blocks, name is 2',7'-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl diacetate, and the molecular formula is C24H14Cl2O7, Computed Properties of 2044-85-1.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Brahmi-Chendouh, Nabila published the artcileA nutraceutical extract from Inula viscosa leaves: UHPLC-HR-MS/MS based polyphenol profile, and antioxidant and cytotoxic activities, Safety of 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate, the main research area is Inula viscosa leaf polyphenol antioxidant nutraceutical cytotoxicity UHPLC HRMS; Chromatography; Depsides; High pressure liquid; Inula; Polyphenols; Tandem mass spectrometry.

Nowadays, advanced extraction techniques and highly sensitive metabolic profiling methods are effectively employed to get new information on plant chem. constituents. Among them wild medicinal plants or their parts, with large and ancient use in folk medicine, are investigated for their potential functional use and cultivation. In this context, Inula viscosa leaves engaged our attention. A simple exptl. design, based on Soxhlet extraction and chromatog. fractionation, allowed us to obtain the investigated polyphenol fraction (IvE). UHPLC-HRMS analyses revealed shikimoyl depsides of caffeic acid and unusual dihydrobenzofuran lignans as main secondary metabolites. These compounds, together with cinchonain-type phenols, and hydroxycinnamoyl flavonol glycosides, are reported for the first time in inula. Overall, forty-three secondary metabolites were identified. The extract exerted a remarkable antiradical activity towards DPPH· and ABTS+·. Furthermore, it was able to inhibit cell viability and mitochondrial redox activity of neuroblastoma, hepatoblastoma and colon carcinoma cells, whereas it did not affect cell d. of HaCaT cells immortalized human keratinocytes. As detected by the oxidant-sensing probe 2′,7′-dichlorodihydrofluorescein diacetate, the inhibitory responses seemed to be related to IvE-induced increase of intracellular reactive oxygen species (ROS). The obtained results highlighted that inula leaves, nowadays even undervalued and unexplored, could be considered a renewable source of nutraceutical compounds

Journal of Food and Drug Analysis published new progress about Antioxidants. 2044-85-1 belongs to class esters-buliding-blocks, name is 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate, and the molecular formula is C24H14Cl2O7, Safety of 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Jugreet, Bibi Sharmeen published the artcileChemical variability, pharmacological potential, multivariate and molecular docking analyses of essential oils obtained from four medicinal plants, Quality Control of 111-11-5, the main research area is essential oil medicinal plant bioactive compound mol docking.

Essential oils (EOs) hold tremendous medicinal attributes and are greatly exploited industrially worldwide. In the present study, the chem. composition of five EOs prepared from four aromatic plants were revealed together with their inhibitory activities against five key clin. enzymes (α-amylase, α-glucosidase, tyrosinase, acetyl- and butyryl-cholinesterase). Limonene (84.3%) and sabinene (38.1%) were the most dominant constituents present in Citrus aurantium fruit peel and leaf EOs resp. Turmerone (31.4%), ar-turmerone (16.1%), and turmerol (14.6%) were the principal components identified in Curcuma longa rhizome EO. Addnl., Morinda citrifolia fruit EO was abundant in octanoic acid (78.9%), while carvacrol (17.9%), δ-3-carene (15.2%), and camphor (12.9%) were predominant in Plectranthus amboinicus EO. The investigated EOs were all active inhibitors of acetylcholinesterase, amylase, and tyrosinase. Morinda citrifolia and P. amboinicus EOs inhibited butyrylcholinesterase exclusively, while M. citrifolia and C. aurantium fruit peel EOs displayed inhibition against glucosidase as well. Due to strong interactions with their active sites, mol. docking showed turmerone followed by carvacrol to have the highest binding affinities with target enzymes. Moderate to strong antioxidant potential was also demonstrated by all EOs. However, P. amboinicus EO presented the most potent antioxidant capacity and contained the highest amount of phenolics, while M. citrifolia EO was the weakest among all. Besides, a strong pos. correlation was noted between EOs’ antioxidant capacities and total phenolic content. With the exception of C. aurantium leaf and C. longa EOs which showed similar bioactivities and were grouped together, the other EOs were subdivided into distinct groups by principal component anal. Altogether, this study highlighted interesting pharmacol. properties of the investigated EOs that could serve as sources of bioactive ingredients with potential industrial applications.

Industrial Crops and Products published new progress about Antioxidants. 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Quality Control of 111-11-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

de Farias Marques, Antonia Dayane Jenyffer published the artcileOxidative stability of chicken burgers using organic coffee husk extract, Recommanded Product: Methyl octanoate, the main research area is Coffee husk extract chicken burger oxidative stability; Lipid oxidation; Meat products; Natural antioxidant; Protein oxidation.

The antioxidant capacity of organic coffee husk extract (Coffee arabica L.) added to chicken burgers was evaluated. Two formulations were prepared: with addition of the extract (100 and 200 ppm CAE/kg), in addition to control formulations without the addition of antioxidant, and with the addition of synthetic antioxidant. The products were characterized by phys. and chem. anal. and analyzed for oxidative stability during 45 days of storage under freezing. The addition of extract in the proportion of 200 ppm CAE/kg of hamburger revealed efficacy against lipid oxidation equivalent to treatment with a synthetic antioxidant. As for protein oxidation, there was no pro or antioxidant influence in the treatments. The addition of organic coffee husk extract to chicken hamburgers is thus indicated, being considered as a potential natural additive. In addition, the use of coffee husks helps to minimize the lager amounts of agro-industrial byproducts generated by the coffee industry.

Food Chemistry published new progress about Antioxidants. 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Recommanded Product: Methyl octanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Odubanjo, Oluwatoyin Veronica published the artcileFatty acid composition and antioxidant effect of coconut oil in Drosophila melanogaster, Product Details of C9H18O2, the main research area is Drosophila coconut oil fatty acid composition antioxidant.

Abstract: Coconut oil (CO) has gained interest in western medicine due to its promising therapeutic approach in the treatment of Alzheimer’s disease as well as combating oxidative stress-induced neurodegeneration. Flies were raised on CO-supplemented diet for 5 days, and the locomotor performance and survival rate were examined afterwards. The antioxidant activity of CO extract was investigated in vitro; in vivo using Drosophila melanogaster and the CO fatty acid (FA) composition quantified using gas-chromatog. mass spectrometry (GC-MS). The survival rate and locomotor performance of the D. melanogaster reduced significantly at higher concentration of CO (1%)-supplemented diet. CO exhibits significant antioxidant ability by scavenging DPPH and ABTS radicals in a dose-dependent manner. Malondialdehyde (MDA) content was also significantly reduced in vitro in a dose-dependent manner. Likewise, groups II and III fed with supplemented 0.1% and 1% CO reduce MDA level significantly (p < 0.05) in AlCl3-induced flies. GC-MS quantification revealed eight FAs with myristoleic acid (C14:0) as the most abundant, followed by stearic acid (C18:0). The major fatty acids established in this study are not retained as fat in the body but used to generate energy. These observed results prove the antioxidant ability of phytochems. in CO. In conclusion, coconut oil is a good source of phenolic compounds and healthy FA that confers its therapeutic use. Comparative Clinical Pathology published new progress about Antioxidants. 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Product Details of C9H18O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chapela, Sebastian P. published the artcileN-Acetyl cysteine improves cellular growth in respiratory-deficient yeast, Category: esters-buliding-blocks, the main research area is acetyl cysteine cellular growth respiratory deficient; Antioxidant effect; Reactive oxygen species (ROS); Yeast.

Reactive oxygen species (ROS) is a main factor that alters cellular physiol. and functionality. Many strategies are used in order to control excessive oxidative stress. One strategy includes the use of antioxidants like N-acetyl cysteine (NAC). The aim of this study was to compare the effect of this antioxidant on ROS production and cellular growth of a wild-type and a respiratory-deficient Saccharomyces cerevisiae strain. Using a simple system such as yeast allows oxidative stress investigations on which numerous factors are more manageable or circumscribed than in a higher organism. We grew cells in a complex medium and incubated them during 72 h. Later, cellular viability and ROS production was evaluated. ROS level was estimated by use of fluorescence signal with 2′,7′-dichlorofluorescein diacetate (DCFH-DA). As it is found in the present work, a reducing environment exerted by NAC presence during incubation of the cells allows a respiratory-deficient Saccharomyces cerevisiae strain to improve its cellular growth. It seems likely that the energy production or the phenotype which characterizes a deficient strain is incapable of palliating ROS growth inhibition while NAC helps to overcome this limitation.

Brazilian Journal of Microbiology published new progress about Antioxidants. 2044-85-1 belongs to class esters-buliding-blocks, name is 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate, and the molecular formula is C24H14Cl2O7, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics