Month: December 2022

Morisawa, Yasuhiro published the artcileStudies on anticoccidial agents. 10. Synthesis and anticoccidial activity of 5-nitronicotinamide and its analogs, Formula: C9H10N2O4, the main research area is coccidiostat nitronicotinamide derivative; nicotinamide derivative anticoccidial.

5-Nitronicotinamide [1462-88-0] and 12 derivatives (I: R1 = H, Cl, Me, OMe, OEt, OPr, OCH2PH, OPh, NHEt, NEt2, NHCH2Ph; R2 = H, Me; R3 = H, Me) were prepared and the parent compound (I; R1 = R2 = R3 = H) and the 2-methyl (I; R1 = Me, R2 = R3 = H) [27715-68-0] and 4-methyl (I; R1 = R3 = H, R2 = Me) [60524-53-0] derivatives had marked to excellent activity against Eimeria tenella, while the 6-methyl derivative (I; R1 = R2 = H, R3 = Me) [60524-54-1] had only slight activity. Of 67 N-substituted derivatives of 5-nitronicotinamide, 21 showed excellent coccidiostatic effects, with optimal activity associated with the N-lower alkyl, alkanoyl, alkenoyl, and aromatic acyl derivatives 5-Nitronicotinamide was prepared from 5-bromonicotinoyl chloride by treatment with NH3 followed by oxidation with fuming H2SO4 and 30% H2O2, while the amide N-substituted derivatives were prepared by conventional means.

Journal of Medicinal Chemistry published new progress about Coccidiosis. 51984-71-5 belongs to class esters-buliding-blocks, name is Ethyl 2-methyl-5-nitro-3-pyridinecarboxylate, and the molecular formula is C9H10N2O4, Formula: C9H10N2O4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Goi, Yohsuke published the artcileDual functions of TEMPO-oxidized cellulose nanofibers in oil-in-water emulsions: Pickering emulsifier and unique dispersion stabilizer, Formula: C11H22O2, the main research area is TEMPO oxidized cellulose nanofiber oil water emulsion Pickering emulsifier; dispersion stabilizer.

The emulsifying and dispersing mechanisms of oil-in-water emulsions stabilized by 2,2,6,6-tetramethylpiperidin-1-oxyl (TEMPO)-oxidized cellulose nanofibers (CNFs) have been investigated. The emulsifying mechanism was studied by changing the oil/water interfacial tension from 8.5 to 53.3 mN/m using various types of oils. The results showed that the higher the oil/water interfacial tension, the greater is the amount of CNFs adsorbed at the oil/water interface, making the CNF-adsorbed oil-in-water emulsions thermodynamically more stable. Moreover, the amount of CNFs adsorbed on the surfaces of the oil droplets increased with increasing interfacial area. The dispersion stability of the oil droplets was dominated by the CNF concentration in the water phase. Above the critical concentration (0.15% weight/weight), the CNFs formed network structures in the water phase, and the emulsion was effectively stabilized against creaming. Emulsion formation and the CNF network structures in the emulsion were visualized by cryo-SEM.

Langmuir published new progress about Coalescence. 110-42-9 belongs to class esters-buliding-blocks, name is Methyl decanoate, and the molecular formula is C11H22O2, Formula: C11H22O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Shibata, Motoki published the artcileMicellar aggregation and thermogelation of amphiphilic random copolymers in water hierarchically dependent on chain length, Related Products of esters-buliding-blocks, the main research area is micellar aggregation amphiphilic polymethacrylate hierarchical.

Micellar aggregates and thermoresponsive gelation of amphiphilic random copolymers in water were examined in detail, focused on effects of the d.p. (DP) on the behavior. For this purpose, we designed random copolymers carrying hydrophilic poly(ethylene glycol) and hydrophobic dodecyl groups, where the DP was varied from 63 to 358. The content of the hydrophobic monomer was set to 60 mol% to facilitate thermogelation. All the copolymers formed multichain aggregates in water, while the size distribution depended on DP. Since copolymers with larger DP had less composition distribution, the copolymers with 145 or more of DP formed size-controlled aggregates in water. Their concentrated solutions, above the overlap concentration of the aggregates, gelled entirely upon heating, followed by syneresis. In contrast, the short copolymer with 63 of DP formed aggregates with multimodal size distribution, and the concentrated solution underwent macroscopic phase separation upon heating, followed by gelation of the polymer-rich lower layer. As confirmed by small-angle neutron scattering, the copolymer suitable for thermogelation originally formed aggregates consisting of multiple micelle subunits in the aqueous dilute solution, and the thermogelation of the concentrated solution was driven by the phys. packing of the micelle subunits upon heating. Thus, we revealed that the DP hierarchically affected not only the self-assembly of the copolymers into size-controlled micellar aggregates in water but also the thermogelation of the concentrated solutions via intermicellar association

European Polymer Journal published new progress about Cloud point. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, Related Products of esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tufariello, Maria published the artcileEfficacy of yeast starters to drive and improve Picual, Manzanilla and Kalamata table olive fermentation, Category: esters-buliding-blocks, the main research area is olive fermentation yeast; fermentation; quality; safety; starter; table olives; yeast.

BACKGROUND : Table olive fermentation is an unpredictable process and frequently performed using traditional practices often inadequate to obtain products with acceptable quality and safety standards In the present study, the efficacy of selected yeast strains as starters to drive fermentations of green and black table olives by the Greek method was investigated. Pilot-scale production by spontaneous fermentation as a control, olives started with previously selected Saccharomyces cerevisiae strains and fermentation driven by com. S. cerevisiae baker’s yeast strain were carried out for each of Manzanilla, Picual and Kalamata table olive cultivars. RESULTS : Time of fermentation was significantly shortened to 40 days to complete the transformation process for all three tested cultivars. Inoculated table olives were enhanced in their organoleptic and nutritional properties in comparison with corresponding samples obtained by spontaneous fermentation The use of starters was also able to improve safety traits of table olives in terms of biogenic amine reduction as well as absence of undesired microorganisms at the end of the process. CONCLUSIONS : Autochthonous, but also non-autochthonous, yeasts can be used to start and control table olive fermentations and can significantly improve quality and safety aspects of table olives produced by many smallholder farmers. © 2018 Society of Chem. Industry.

Journal of the Science of Food and Agriculture published new progress about Clostridium. 106-32-1 belongs to class esters-buliding-blocks, name is Ethyl octanoate, and the molecular formula is C10H20O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ravichandran, Janani published the artcileAn atlas of fragrance chemicals in children’s products, Related Products of esters-buliding-blocks, the main research area is atlas fragrance chem product children potential health concern safety; Chemical regulation; Children’s products; FCCP database; Fragrance chemicals; Network analysis; Skin sensitizing chemicals.

Exposure to environmental chems. during early childhood is a potential health concern. At a tender age, children are exposed to fragrance chems. used in toys and child care products. Although there are few initiatives in Europe and United States towards monitoring and regulation of fragrance chems. in children’s products, such efforts are still lacking elsewhere. Besides there was no systematic effort to create a database compiling the surrounding knowledge on fragrance chems. used in children’s products from published literature. Here, we built a database of Fragrance Chems. in Children’s Products (FCCP) that compiles information on 153 fragrance chems. from published literature. The fragrance chems. in FCCP were classified based on their chem. structure, children’s product source, chem. origin and odor profile. Moreover, we have also compiled the physicochem. properties, predicted Absorption, Distribution, Metabolism, Excretion and Toxicity (ADMET) properties, mol. descriptors and human target genes for the fragrance chems. in FCCP. After building FCCP, we performed multiple analyses of the associated fragrance chem. space. Firstly, we assessed the regulatory status of the fragrance chems. in FCCP through a comparative anal. with 21 chem. lists reflecting current guidelines or regulations. We find that several fragrance chems. in children’s products are potential carcinogens, endocrine disruptors, neurotoxicants, phytotoxins and skin sensitizers. Secondly, we performed a similarity network based anal. of the fragrance chems. in children’s products to reveal the high structural diversity of the associated chem. space. Lastly, we identified skin sensitizing fragrance chems. in children’s products using ToxCast assays. In a nutshell, we present a comprehensive resource and detailed anal. of fragrance chems. in children’s products highlighting the need for their better risk assessment and regulation to deliver safer products for children. FCCP is accessible at: https://cb.imsc.res.in/fccp.

Science of the Total Environment published new progress about Carcinogens. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Related Products of esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Xu, Xuetao published the artcileOil-polluted water purification via the carbon-nanotubes-doped organohydrogel platform, Formula: C16H30O2, the main research area is carbon organohydrogel thermal management solar driven water purification.

Solar-driven evaporators are promising for tackling freshwater scarcity but still challenged in simultaneously realizing comprehensive performances at one platform for sustainable and efficient application in real-world environments, such as stable-floating, scalability, salt-resistance, efficient vaporization, and anti-oil-fouling property. Herein, we design a hybrid organohydrogel evaporator to achieve the enduring oil contamination repulsion with maintaining accelerated evaporation process, and integrate capacities of ultra-stable floating, hindered salt-crystallization, large-scale fabrication for practical purification of seawater and polluted solutions The raised water surface surrounding evaporators, induced by low d. of organogel-phase, results in oil contamination resistance through the lateral capillary repulsion effect. Meanwhile, the organogel-phase containing photo-thermal carbon-nanotubes with low thermal capacity and conduction can form locally confined hot dots under solar irradiation and reduce heat dissipation on heating excessive water. Therefore, based on this approach, accelerated long-term practical purification of oil-contaminated solutions without any extra disposal is realized. Considering other properties of ultra-stable floating, large-scale fabrication, and anti-salt crystallization, these innovative organohydrogel evaporators open pathways for purifying oil-slick-polluted water via interfacial evaporation and are anticipated accelerating industrialization of efficient and sustainable solar-driven water purification

Nano Research published new progress about Capillarity. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, Formula: C16H30O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Xiang, Ming-Yue published the artcileLimited Fraction of Crystallized Side Chains in Bottlebrush Poly(n-alkyl methacrylate)s, Recommanded Product: Dodecyl 2-methylacrylate, the main research area is bottle brush polyalkyl methacrylate crystallization side chain.

Crystallinity of bottlebrush polymers due to side chain crystallization has been considered to be related to the length of the side chains only under the assumption of complete participation of crystallization by all side chains. Recent exptl. results revealed that in poly(n-alkyl methacrylate)s a fraction of side chains could not crystallize due to constraints imposed by the trapped main chain entanglements and required expansion of main chain-main chain distance. This result renders the original simplified consideration of the origin of crystallinity in bottlebrush polymers questionable. In this work, we introduce a new parameter fc, the fraction of crystallizable side chains, to better describe the crystallinity of bottlebrush polymers. A linear relationship between the melting enthalpy and the number of alkyl groups in side chains for bottlebrush polymers reported repeatedly indicates that fc remains essentially unchanged when bottlebrush polymers had the same main chain structure and grafting degree but different side chain lengths. The slope of the above-mentioned linear relationship is thus ΔHCH2 × fc, where ΔHCH2 stands for the melting enthalpy of one mole alkyl group packed into the crystal. With a known value of fc, it is possible to estimate the value of ΔHCH2. In case of poly(n-alkyl methacrylate)s, we estimated ΔHCH2 of hexagonal crystal being at most 5.74 kJ/mol with the knowledge of possibly smallest fc of 0.67 obtained from small angle X-ray scattering data. Therefore, the crystallinity of bottlebrush polymer would be calculated based on the equation Xc = fc × (Nc/N) with N and Nc being the number of alkyl groups in a side chain and those packed in the crystalline structure, resp. Both chem. structure and grafting degree of bottlebrush polymers affect fc.

Chinese Journal of Polymer Science published new progress about Callistemon. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, Recommanded Product: Dodecyl 2-methylacrylate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mezo, Emerencia published the artcileThe role of ionic liquid interaction in the separation of fatty acid methyl esters-polyunsaturated geometric isomers in GC-MS, COA of Formula: C23H46O2, the main research area is fatty acid methyl ester ionic liquid chromatog column interaction.

Knowledge of the type and level of saturated and unsaturated fatty acids in food and clin. matrixes is of practical importance, but the wide variety of fatty acids makes analyses very complex. The discrimination of the geometric isomers of fatty acid needs proper and effective separation conditions. The efficiency of three different stationary phases was evaluated by GC-MS methods in the separation of fatty acids in their Me ester forms. Significant differences were observed in the efficiencies of polysiloxane-based (non-polar HP-5MS and medium/high polarity DB-225MS) and ionic liquid-based (SLB-IL111) columns. Baseline separation of the geometric isomers of linoleic acid Me ester was obtained by the extremely polar SLB-IL111 column, showing a preference over the other two columns. The optimization of the exptl. conditions (response linearity, limit of detection, limit of quantification, system suitability, intraday and interday repeatability and accuracy) showed the separation power of the ionic liquid interaction in the analyses by using short (25-30 m long) columns. By deducting the general principles of the interaction, predictions can be made for the separation of other isomers. The results facilitate the precise identification of various types of fatty acids in real samples for nutritional information.

Separations published new progress about Calibration. 929-77-1 belongs to class esters-buliding-blocks, name is Methyl docosanoate, and the molecular formula is C23H46O2, COA of Formula: C23H46O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mezo, Emerencia published the artcileThe role of ionic liquid interaction in the separation of fatty acid methyl esters-polyunsaturated geometric isomers in GC-MS, Recommanded Product: Methyl octanoate, the main research area is fatty acid methyl ester ionic liquid chromatog column interaction.

Knowledge of the type and level of saturated and unsaturated fatty acids in food and clin. matrixes is of practical importance, but the wide variety of fatty acids makes analyses very complex. The discrimination of the geometric isomers of fatty acid needs proper and effective separation conditions. The efficiency of three different stationary phases was evaluated by GC-MS methods in the separation of fatty acids in their Me ester forms. Significant differences were observed in the efficiencies of polysiloxane-based (non-polar HP-5MS and medium/high polarity DB-225MS) and ionic liquid-based (SLB-IL111) columns. Baseline separation of the geometric isomers of linoleic acid Me ester was obtained by the extremely polar SLB-IL111 column, showing a preference over the other two columns. The optimization of the exptl. conditions (response linearity, limit of detection, limit of quantification, system suitability, intraday and interday repeatability and accuracy) showed the separation power of the ionic liquid interaction in the analyses by using short (25-30 m long) columns. By deducting the general principles of the interaction, predictions can be made for the separation of other isomers. The results facilitate the precise identification of various types of fatty acids in real samples for nutritional information.

Separations published new progress about Calibration. 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Recommanded Product: Methyl octanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mezo, Emerencia published the artcileThe role of ionic liquid interaction in the separation of fatty acid methyl esters-polyunsaturated geometric isomers in GC-MS, Recommanded Product: Methyl decanoate, the main research area is fatty acid methyl ester ionic liquid chromatog column interaction.

Knowledge of the type and level of saturated and unsaturated fatty acids in food and clin. matrixes is of practical importance, but the wide variety of fatty acids makes analyses very complex. The discrimination of the geometric isomers of fatty acid needs proper and effective separation conditions. The efficiency of three different stationary phases was evaluated by GC-MS methods in the separation of fatty acids in their Me ester forms. Significant differences were observed in the efficiencies of polysiloxane-based (non-polar HP-5MS and medium/high polarity DB-225MS) and ionic liquid-based (SLB-IL111) columns. Baseline separation of the geometric isomers of linoleic acid Me ester was obtained by the extremely polar SLB-IL111 column, showing a preference over the other two columns. The optimization of the exptl. conditions (response linearity, limit of detection, limit of quantification, system suitability, intraday and interday repeatability and accuracy) showed the separation power of the ionic liquid interaction in the analyses by using short (25-30 m long) columns. By deducting the general principles of the interaction, predictions can be made for the separation of other isomers. The results facilitate the precise identification of various types of fatty acids in real samples for nutritional information.

Separations published new progress about Calibration. 110-42-9 belongs to class esters-buliding-blocks, name is Methyl decanoate, and the molecular formula is C11H22O2, Recommanded Product: Methyl decanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics