Synthesis of salicylates from anionically activated aromatic trifluoromethyl group was written by Xie, Huilin;Lin, Chuankai;Wang, Ruixiang;Liu, Jin-Biao. And the article was included in Tetrahedron Letters in 2022.HPLC of Formula: 118-61-6 This article mentions the following:
An efficient approach to salicylates via a novel transformation of anionically activated aromatic trifluoromethyl group is described. 2-(Trifluoromethyl)phenol reacts with phenols/alcs. under alk. conditions to afford the corresponding aryl/alkyl salicylates in high yields. Mechanism studies indicated that the carbonyl oxygen atom of ester is from the H2O in the solvent. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxybenzoate (cas: 118-61-6HPLC of Formula: 118-61-6).
Ethyl 2-hydroxybenzoate (cas: 118-61-6) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.HPLC of Formula: 118-61-6
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics