Application of palladium-catalyzed aryl C-H alkylation in total synthesis of (-)-berkelic acid was written by Wang, Hui-Hong;Wang, Xiao-Dong;Cao, Fei;Gao, Wei-Wei;Ma, Shu-Meng;Li, Zhao;Deng, Xue-Mei;Shi, Tao;Wang, Zhen. And the article was included in Organic Chemistry Frontiers in 2021.Recommanded Product: Methyl2-methylbutyrate This article mentions the following:
An unprecedented palladium(II)-catalyzed ortho-alkylation of N-methoxybenzamide RC(O)NHOCH3 (R = C6H5, 3-ClC6H4, 2,4-(OCH3)2C6H3, etc.) with epoxides like 2-pentyloxirane has been applied to the total synthesis of the isochroman natural product (-)-berkelic acid. Combining this strategy with a well documented spiroacetalization cascade reaction, (-)-berkelic acid is obtained in 13.9% overall yield with the longest linear sequence of 11 steps. The results of preliminary biol. studies on the synthesized natural product and its analogs are also reported. In the experiment, the researchers used many compounds, for example, Methyl2-methylbutyrate (cas: 868-57-5Recommanded Product: Methyl2-methylbutyrate).
Methyl2-methylbutyrate (cas: 868-57-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: Methyl2-methylbutyrate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics