Su, Jing et al. published their research in Bioorganic & Medicinal Chemistry in 2007 | CAS: 16413-26-6

3-Cyanophenylisocyanate (cas: 16413-26-6) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Quality Control of 3-Cyanophenylisocyanate

SAR study of bicyclo[4.1.0]heptanes as melanin-concentrating hormone receptor R1 antagonists: Taming hERG was written by Su, Jing;McKittrick, Brian A.;Tang, Haiqun;Burnett, Duane A.;Clader, John W.;Greenlee, William J.;Hawes, Brian E.;O’Neill, Kim;Spar, Brian;Weig, Blair;Kowalski, Timothy;Sorota, Steve;Li, Cheng;Liu, Tongtong. And the article was included in Bioorganic & Medicinal Chemistry in 2007.Quality Control of 3-Cyanophenylisocyanate This article mentions the following:

Analogs of the (arylureido)(cyanophenyl)bicyclo[4.1.0]heptane I are prepared in order to increase their melanin-concentrating hormone receptor R1 (MCH1) antagonist activities and to minimize their inhibition of the hERG potassium channel (inhibition of which is a potential source of QTc prolongation and of sudden cardiac death). Introduction of new side chains with basic nitrogen atoms improve the in vitro and ex vivo binding of bicycloheptanes to MCH1; attenuation of the basicity of nitrogen on the side chain and the introduction of a polar group such as aminomethyl on the aryl ring directly attached to the bicyclo[4.1.0]heptane ring decrease the inhibition of hERG by the MCH1 antagonists. Analogs in which the arylbicyclo[4.1.0]heptane ring is replaced with a heteroaryl-substituted cyclohexene ring, such as II, show excellent ex vivo MCH1 antagonism with significant reduction of hERG inhibition. In the experiment, the researchers used many compounds, for example, 3-Cyanophenylisocyanate (cas: 16413-26-6Quality Control of 3-Cyanophenylisocyanate).

3-Cyanophenylisocyanate (cas: 16413-26-6) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Quality Control of 3-Cyanophenylisocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics