11,12-Secoprostaglandins. 3. 8-Alkylthio(sulfinyl and sulfonyl)-12-hydroxyalkanoic acids and related compounds was written by Smith, Robert L.;Bicking, John B.;Gould, Norman P.;Lee, Ta-Jyh;Robb, Charles M.;Kuehl, Frederick A. Jr.;Mandel, Lewis R.;Cragoe, Edward J. Jr.. And the article was included in Journal of Medicinal Chemistry in 1977.Related Products of 62020-09-1 This article mentions the following:
Seven title compounds with structural features of 11,12-secoprostaglandins were prepared and tested for prostaglandin E mimicry in stimulating cyclic AMP [60-92-4] in the mouse ovary and in binding to the rat lipocyte prostaglandin receptor. The most active compound, 8-(methylsulfonyl)-12-hydroxyheptadecanoic acid (I) [59768-16-0], markedly stimulated cyclic AMP formation in the mouse ovary and human psoriatic skin slices, showed significant affinity for a prostaglandin receptor, and effectively inhibited antigen-induced lymphocyte transformation. I is not a substrate for 15-hydroxyprostaglandin dehydrogenase and is not a phosphodiesterase inhibitor. Structure-activity relations are discussed. In the experiment, the researchers used many compounds, for example, Methyl 2-(methylsulfonyl)acetate (cas: 62020-09-1Related Products of 62020-09-1).
Methyl 2-(methylsulfonyl)acetate (cas: 62020-09-1) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Related Products of 62020-09-1
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics