Cyclization of 5-alkynones with chromium alkylidene equivalents generated in-situ from gem-dichromiomethanes was written by Murai, Masahito;Taniguchi, Ryuji;Kurogi, Takashi;Shunsuke, Moritani;Takai, Kazuhiko. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020.Application In Synthesis of Diethyl 2-(prop-2-yn-1-yl)malonate This article mentions the following:
A rare example of cyclization with 5-alkynones, which possess non-polar alkynyl and less electrophilic polar keto carbonyl groups, was demonstrated. The key to promoting carbene/alkyne metathesis followed by alkylidenation with pendant C=O double bonds was the Schrock-type nucleophilic reactivity of the generated chromium carbene equivalent from readily available diiodomethanes and CrCl2 by simple heating. In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Application In Synthesis of Diethyl 2-(prop-2-yn-1-yl)malonate).
Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application In Synthesis of Diethyl 2-(prop-2-yn-1-yl)malonate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics