Relationship between the effects on bactericidal activity of selected disinfectants and the hydrophobic characters of dibasic acid diesters was written by Furuta, Taro;Kihara, Koji. And the article was included in Chemical & Pharmaceutical Bulletin in 1992.Application of 1190-39-2 This article mentions the following:
Test solutions which contained 80% EtOH and 0.2% chlorhexidine (CH) or benzalkonium chloride (BC) were prepared with or without a dibasic acid diester. After complete evaporation of the EtOH from the solution on filter paper, an overnight broth culture (Staphylococcus aureus) was repeatedly inoculated onto the filter paper and viable bacterial counts were measured at 5 min after the last inoculation. By comparison with viable counts for CH or BC alone, the potentiating effects of dibasic acid diesters on the bactericidal activity of CH or BC were estimated The activity of the 2 disinfectants was potentiated in the presence of certain homologs of di-n-Bu esters of aliphatic dibasic acids and di-alkyl esters of adipic and phthalic acids. Diisobutyl adipate, one of the most effective diesters, substantially enhanced the bactericidal activities of benzethonium chloride, cetyl pyridinium chloride, and didecyl di-Me ammonium chloride, as well as CH and BC, but not those of polyhexamethylene biguanide or alkyldiaminoethyl glycinate. The potentiating effects of dibasic acid diesters observed for both CH and BC seemed to be affected by the hydrophobic character of these diesters themselves and are also expressed well by a particular quadratic equation as a function of these characters: namely, capacity factors, as determined by HPLC. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Application of 1190-39-2).
malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Application of 1190-39-2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics