Coeck, Robin published the artcileOne-pot reductive amination of carboxylic acids: a sustainable method for primary amine synthesis, SDS of cas: 111-11-5, the main research area is carboxylic acid one pot reductive amination primary amine synthesis; ruthenium tungsten bimetallic catalyst green solvent.
The reductive amination of carboxylic acids is a very green, efficient and sustainable method for the production of (bio-based) amines. However, with current technol., this reaction requires two to three reaction steps. Here, we report the first (heterogeneous) catalytic system for the one-pot reductive amination of carboxylic acids to amines, with solely H2 and NH3 as the reactants. This reaction can be performed with relatively cheap ruthenium-tungsten bimetallic catalysts in the green and benign solvent cyclopentyl Me ether (CPME). Selectivities of up to 99% for the primary amine could be achieved at high conversions. Addnl., the catalyst is recyclable and tolerant for common impurities such as water and cations (e.g. sodium carboxylate).
Green Chemistry published new progress about Carboxylic acids Role: RCT (Reactant), RACT (Reactant or Reagent) (C4-C14). 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, SDS of cas: 111-11-5.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics