Vielhaber, Thomas published the artcileManganese-catalyzed homogeneous hydrogenation of ketones and conjugate reduction of α,β-unsaturated carboxylic acid derivatives: A chemoselective, robust, and phosphine-free in situ-protocol, Synthetic Route of 103-26-4, the publication is Applied Catalysis, A: General (2021), 118280, database is CAplus.
A user-friendly and glove-box-free catalytic protocol for the manganese-catalyzed hydrogenation of ketones RC(O)R1 (R = Ph, 2-chlorophenyl, pyridin-3-yl, etc.; R1 = Me, Et, Ph, etc.; RR1 = -(CH2)5-, -(CH2)4-), 3-methylcyclohexan-1-one, isophorone and 1-indanone and conjugated C=C-bonds of esters and nitriles R2C(R3)=C(R4)R5 (R2 = Ph, 4-bromophenyl, 3-cyanophenyl, etc.; R3 = H, Ph; R4 = methoxycarbonyl, (prop-2-en-1-yloxy)carbonyl, Ph, etc.; R5 = H, ethoxycarbonyl, CN) was communicated. The resp. catalyst is readily assembled in situ from the privileged [Mn(CO)5Br] precursor and cheap 2-picolylamine. The catalytic transformations were performed in the presence of t-BuOK whereby the corresponding hydrogenation products were obtained in good to excellent yields. The described system offers a brisk and atom-efficient access to both secondary alcs. (RCH(OH)R1, cyclohexanol, 3,5,5-trimethylcyclohex-2-en-1-ol and 1-indanol) and saturated esters R2(R3)CHCH(R4)R5 avoiding the use of oxygen-sensitive and expensive phosphine-based ligands.
Applied Catalysis, A: General published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C6H10O3, Synthetic Route of 103-26-4.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics