Sun, Ping published the artcileDevelopment of new HPLC chiral stationary phases based on native and derivatized cyclofructans, Category: esters-buliding-blocks, the publication is Analytical Chemistry (Washington, DC, United States) (2009), 81(24), 10215-10226, database is CAplus and MEDLINE.
An unusual class of chiral selectors, cyclofructans, is introduced for the 1st time as bonded chiral stationary phases. Compared to native cyclofructans (CFs), which have rather limited capabilities as chiral selectors, aliphatic- and aromatic-functionalized CF6s possess unique and very different enantiomeric selectivities. Indeed, they sep. a very broad range of racemic compounds In particular, aliphatic-derivatized CF6s with a low substitution degree baseline sep. all tested chiral primary amines. It appears that partial derivatization on the CF6 mol disrupts the mol. internal hydrogen bonding, thereby making the core of the mol. more accessible. In contrast, highly aromatic-functionalized CF6 stationary phases lose most of the enantioselective capabilities toward primary amines, however they gain broad selectivity for most other types of analytes. This class of stationary phases also demonstrates high loadability and therefore has great potential for preparative separations The variations in enantiomeric selectivity often can be correlated with distinct structural features of the selector. The separations occur predominantly in the presence of organic solvents.
Analytical Chemistry (Washington, DC, United States) published new progress about 126613-06-7. 126613-06-7 belongs to esters-buliding-blocks, auxiliary class Chiral Diphenols, name is (R)-[1,1′-Binaphthalene]-2,2′-diyl bis(trifluoromethanesulfonate), and the molecular formula is C2H2N4O2, Category: esters-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics