Hobdy, Erole’s team published research in Current Opinion in Investigational Drugs (Thomson Scientific) in 5 | CAS: 122110-53-6

Current Opinion in Investigational Drugs (Thomson Scientific) published new progress about 122110-53-6. 122110-53-6 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester,Inhibitor, name is (Pivaloyloxy)methyl butyrate, and the molecular formula is C10H18O4, Recommanded Product: (Pivaloyloxy)methyl butyrate.

Hobdy, Erole published the artcileAN-9 (Titan), Recommanded Product: (Pivaloyloxy)methyl butyrate, the publication is Current Opinion in Investigational Drugs (Thomson Scientific) (2004), 5(6), 628-634, database is CAplus and MEDLINE.

A review. Titan is developing AN-9 for the potential treatment of various cancers. AN-9 is a histone deacetylase inhibitor analog of butyric acid that causes apoptosis of cancer cells through signaling cellular differentiation. In Mar. 2001, a phase I/II study involving patients with liver tumors was initiated. By Nov. 2001, enrollment had been completed in a second phase II study of refractory non-small-cell lung cancer (NSCLC). In June 2003, Titan began enrollment for a phase IIb trial of AN-9 in combination with docetaxel in patients with NSCLC.

Current Opinion in Investigational Drugs (Thomson Scientific) published new progress about 122110-53-6. 122110-53-6 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester,Inhibitor, name is (Pivaloyloxy)methyl butyrate, and the molecular formula is C10H18O4, Recommanded Product: (Pivaloyloxy)methyl butyrate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics